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 | | R. Howard Berg, Ph.D.
Director, Integrated Microscopy Facility,
Danforth Plant Science Center, St. Louis, Missouri, USA |
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"The new fast confocal system from Carl Zeiss is a tremendous scientific tool that will help in gathering new insights into fast processes of living specimens, including plants. No longer will spatial resolution have to be sacrificed for temporal resolution."
 | | Dr. Roland Nitschke
Director, Life Imaging Center, Biology I,
Freiburg University, Germany |
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"The LSM 5 LIVE will open exiting experimental possibilities. The main use in our imaging facility will be for ultrafast ratiometric Ca2+-measurements on neuronal cultures in combination with optical manipulation, observation of cilial beating in fluorescence and transmitted light in real time, tracking of apical to basolateral transport in epithelial cells in 4D, and screening of large objects at highest optical resolution in 4D. The software of the LSM 5 LIVE will already be familiar to LSM 510 users, allowing easy access and full use of the instrument from the start."
 | | Dr. Spencer Shorte
PFID, Pasteur Institute, Paris, France |
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"We had the opportunity to test a prototype of the LSM 5 LIVE and were aghast at its benchmark speed performance. Using low light imaging in living GFP labeled samples that are representative of much of the work we do here every day, we observed imaging speeds of up to 100 full frames per second, displaying minimal photobleaching and high signal-to-noise. Combined coordinately with fast piezo-driven axial Z-sampling, clearly these types of sampling rate promise that the system should prove to be a landmark for multi-dimensional 4D imaging studies in cells and tissues."
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