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Contact-free manipulation and
microdissection with lasers |
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Optical Tweezers are a highly effective and non-invasive method to manipulate cells as well as trap, move, and sort microscopic particles.
Using the force field of a highly focused laser beam (optical trap), manipulation functions are conducted without mechanical contact. Living cells can be manipulated either in isolation or amongst other cells without damage to their structure or function. The wavelength of the applied infra-red lasers is 1064 nm and therefore within medical technology’s “therapeutic window” of 600 nm to 1200 nm for preventing damage to living systems.
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Literature
Ashkin, Arthur: Optical trapping and manipulation of neutral particles using lasers, Proc. Natl. Acad. Sci. Volume 94, pp. 4853–4860 (1997)
Kuyper, Christopher L. and Chiu, Daniel T.: Optical trapping: A versatile technique for biomanipulation, Applied Spectroscopy, 2002, Volume 56,
Number 11: 300A–312A |
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