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Science Magazine Regulation of Phagosome Maturation by Signals from Toll-Like Receptors

By J. Magarian Blander and Ruslan Medzhitov in Science Magazine 304:1014-1018 (2004).

The authors studied the mechanism of phagocytosis in higher metazoans. They found, that for the phagocytosis of bacterial but not for apoptotic cells a Toll-like receptor signaling pathway is activated.
Acquired with the 3D Deconvolution module
CHO cells CHO cells
Chinese hamster ovarian cells are shown before and after deconvolution.
FISH-Analysis FISH-Analysis
A single nucleus from an ovary carcinoma sample was hybridized with 5 FISH probes and counterstained with DAPI (white).
4µm Fluobead 4µm Fluobead
You can see a fluorescent bead with a diameter of 4µm (Molecular Probes TetraSpeck™, T14792) before and after deconvolution.
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Deconvolution
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