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| * all movies with kind permission of the authors |
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Live movie of a kidney section of a living rat
The rat had been injected with 500 Kd fluorescein dextran, 3 Kd Texas Red dextran and DAPI. The large fluorescein dextran is excluded by the glomerulus, and confined to blood vessels. The moving shadows in the blood vessels result from the rapid passage of blood cells (300 microns per second). The TexasRed dextran is freely filtered into the kidney tubules, where it is internalized into endosomes of the proximal tubule, but primarily concentrated in the lumen.
Drs. Ken Dunn & Bruce Molitoris
Indiana University School of Medicine, USA
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