 | 1903 M.v. Smoluchowski explains the interrelation between autocorrelation and Brownian movement. |
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 | 1972 The first fluorescence correlation spectrometers - developed in the laboratories of Cornell University, Ithaca, NY, USA and at the Max-Planck-Institute, Göttingen, Germany. |
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 | 1988 The first confocal instrument using a microscope set up for FCS measurements - developed at the Karolinska Institute, Stockholm , Sweden. |
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 | 1996 Carl Zeiss introduces the world’s first automated fluorescence correlation spectrometer, the ConfoCor 1 |
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 | 1999 Carl Zeiss sets the standard for fully automated dual channel cross-correlation spectrometry: the  ConfoCor 2. |
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 | 2000 The age of biophysics dawns in cell biology with the ConfoCor 2/LSM 510 META combi, an innovative module that makes an ingenious technology available to a wide range of users |
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 | 2005 Carl Zeiss introduces the ConfoCor 3, a module tailor-made for observing live cell applications through its direct attachment to a channel of the LSM detection module. |