A preterm baby with gestational age 28 weeks, birth weight 1400 grams and post menstrual age 35 weeks
Both eyes Aggressive Posterior Retinopathy of Prematurity (APROP) with tortuous and dilated vessels in Zone 1 with extensive looping, shunting of vessels and areas of neovascularization. Right eye shows temporal extensive avascular retina. However, the left eye disease looks more severe than right eye. Left eye also shows inferior lid artifact.
Baby was advised intravitreal anti-VEGF (anti-Vascular Endothelial Growth Factor) injection in both the eyes on the same day. Post injection follow up at 1-week showed reduced plus disease, decreasing tortuosity of vessels and reducing neovascular fronds.