A preterm baby with gestational age 30 weeks, birth weight 1700 grams and post menstrual age 35 weeks
Both eyes show angry looking Zone 1 Stage 3 Aggressive Posterior Retinopathy of Prematurity (APROP) with severe plus with shunting and looping of vessels. The macula is just vascularized in the right eye, and yet to be completely vascularized in the left eye. Both eyes show inferior lower eyelid artifact.
Baby was advised intravitreal anti-VEGF (anti-Vascular Endothelial Growth Factor) injection in both the eyes on the same day. Post injection follow up at 1-week showed reduced plus disease with decreasing tortuosity of vessels. At 1-month follow-up the vascular tortuosity and plus had significantly reduced but the vascular progression was still on a slower side with vessels just at Zone 2 posterior.