A preterm baby with gestational age 32 weeks, birth weight 1600 grams and post menstrual age 36 weeks
Both eyes Aggressive Posterior Retinopathy of Prematurity (APROP) with tortuous and dilated vessels in Zone 1 with extensive looping, shunting of vessels and areas of neovascularization. Right eye in addition has few hemorrhages at the superior arcade with extensive avascular retina seen in the superior half. Right eye shows inferior lid artifact.
Baby was advised intravitreal anti-VEGF (anti-Vascular Endothelial Growth Factor) injection in both the eyes on the same day. Post injection follow up at 1-week showed reduced plus disease with decreasing tortuosity of vessels. At 3-week follow-up the vascular loops had opened, and the vessels were advancing to Zone 2.