A preterm baby with gestational age 34 weeks, birth weight 1700 grams and post menstrual age 40 weeks
Both eyes Zone 2 posterior Stage 3 plus Hybrid Retinopathy of Prematurity (ROP). Left eye looks more severe than right eye with looping and shunting of vessels temporally with few hemorrhages.
Baby was advised intravitreal anti-VEGF (anti-Vascular Endothelial Growth Factor) injection in both the eyes on the same day. Post injection follow up at 1-week showed reduced plus disease, decreasing tortuosity of vessels and loops had opened, allowing the vessels to reach Zone 2 in both eyes. At 1-month follow-up the vessels had rapidly reached Zone 3.