A preterm baby with gestational age 34 weeks, birth weight 1800 grams and post menstrual age 39 weeks

Both eyes Aggressive Posterior Retinopathy of Prematurity (APROP) with tortuous and dilated vessels in Zone 1 with extensive looping and shunting of vessels with areas of neovascularization, hemorrhages and ridge formation with avascular temporal retina. The left eye looks more severe with more areas of neovascularization and vitreous condensation.
 

Baby was advised intravitreal anti-VEGF (anti-Vascular Endothelial Growth Factor) injection in both the eyes on the same day. Post injection follow up at 1-week showed reduced plus disease with decreasing tortuosity of vessels and reducing preretinal hemorrhages.