A preterm baby with gestational age 34 weeks, birth weight 1900 grams and post menstrual age 39 weeks

Both eyes Zone 2 posterior Stage 3 Hybrid plus Retinopathy of Prematurity (ROP) with dilated and tortuous vessels with extensive fronds of neovascular tufts temporally. Disease severity looks comparable in both the eyes. Left eye lower lid artifact is seen.

Baby was advised intravitreal anti-VEGF (anti-Vascular Endothelial Growth Factor) injection in both the eyes on the same day. Post injection follow up at 1-week showed reduced plus disease, decreasing tortuosity of vessels and reducing neovascular fronds.