Infographic: Intraoperative Radiotherapy in Brain Tumor Treatment

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What are the effects of Intraoperative Radiotherapy (IORT) on time and precision in brain tumor treatment? Conventional external radiotherapy modalities imply treatment pitfalls, such as a relatively broad irradiation reach potentially affecting healthy tissue1,2 or the need for a delayed start of radiotherapy after resection favoring growth of residual tumor cells3,4. IORT is an alternative treatment option with the potential to minimize these pitfalls already today.

Download the infographic to learn more about recent study results on IORT and its general value for the treatment of brain tumors and metastases.

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  • 1 Vargo, J. A., et al. (2018). Feasibility of dose escalation using intraoperative radiotherapy following resection of large brain metastases compared to postoperative stereotactic radiosurgery. Journal of Neuro-Oncology, 140(2), 413-420. DOI: 10.1007/s11060-018-2968-4.
  • 2 Scoccianti, S., et al. (2015). Organs at risk in the brain and their dose-constraints in adults and in children: A radiation oncologist’s guide for delineation in everyday practice. Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology, 114(2), 230-238. DOI: 10.1016/j.radonc.2015.01.016
  • 3 Minniti, G., et al. (2021). Current status and recent advances in resection cavity irradiation of brain metastases. Radiation Oncology, 16, 73. DOI: 10.1186/s13014-021-01802-9.
  • 4 Barker, E. H., et al. (2015). The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence. Nature Reviews Cancer, 15(7), 409-425. DOI: 10.1038/nrc3958.