OCTA is best for assessing pathology with flow, for e.g. neovasularization, or areas where there is a lack of flow, such as ischemia. OCTA is not suited for assessing pathology without flow such as vitreomacular traction (VMT), epiretinal membrane (ERM), etc., as this may not get picked up on the scan. If leakage information is needed, the standard of care is fluorescein angiography. OCTA is also not ideal for assessing structural issues, for e.g. activity in the choroid or for eyes with poor media such as cataract. However, if you are interested in tracking the foveal avascular zone (FAZ) for these conditions, OCTA may be a good solution.