Radiation therapy is an important element of the breast-conserving treatment for the mamma carcinoma. With intraoperative radiation therapy, radiation is given with a spherical applicator targeted to the area where the risk of recurrence is highest, directly into the tumor bed right after tumor resection. The effectiveness of the TARGIT method is confirmed by the TARGIT-A study and is already used in many breast cancer centers worldwide.1
Kypho-IORT, a combination of intraoperative radiation and Kyphoplasty, enables the sterilization of the metastasis, offering immediate stabilization with pain reduction and at the same time avoiding damage to the healthy spinal cord. The combined procedure of Kypho-IORT offers immediate structural stabilization and provides local control of the tumor growth.2
The versatility of the INTRABEAM® is also displayed in the treatment of skin cancer with electronic brachytherapy. For the treatment of non-melanoma skin cancer, kilovoltage irradiation is an important therapeutic option which is also suitable for patients with a high operative risk.3
A complete resection of gastrointestinal tumors is sometimes not possible for many patients. By using intraoperative radiation with the INTRABEAM®, the local control of recurrent colorectal tumors and advanced local tumors can be improved.4
In general, for IORT no differences in postoperative complications compared to EBRT have been found.5 This is a result of different factors: first, due to the precise and targeted delivery of radiation directly and only to the target volume, and second, with IORT from ZEISS the normal tissue and sensitive structures in the head and neck area can be spared.
As third device generation of IORT from ZEISS, the new INTRABEAM 600 is the first fully integrated and connected treatment platform for IORT addressing multiple clinical needs in one solution.
The second device generation of IORT from ZEISS is the INTRABEAM System*, which is the only intraoperative radiation device used for the Phase III randomized trial "TARGIT-A" with more than 12 years of clinical study expertise.
In each IORT the best possible irradiation of the tumor or the tumor bed respectively the irradiation of non-melanoma skin tumors using electronic brachytherapy has to be ensured. Hence, ZEISS offers multiple applicators which ensure, depending on the type, size and shape of the tumor, an adapted dose distribution to the target tissue.
For INTRABEAM® users, the TARGIT Academy offers a practical first hand training course including an intensive hands-on training which is conducted on a peer-to-peer basis from experts for experts in the field of IORT/ electronic brachytherapy. Due to the fact that the learning curve increases immediately the TARGIT Academy is equally suitable for all users.
The COMPLETE Service for the INTRABEAM® is an individual service package consisting of specialized service units according to customer requests, a straightforward device loaner concept and regular on-site inspections. With this concept an exact performance of the radiation therapy can be ensured at the customer site.