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ZEISS OVD Portfolio

The power of choice at every step

Based on 20+ years experience, development and production, ZEISS provides a state-of-the-art ophthalmic viscosurgical devices (OVD) portfolio that supports your work at each step of the ophthalmic procedure. ZEISS OVDs originate from bacterial fermentation.1

Product overview

ZEISS OVDs VISTHESIA and VISTHESIA intra

ZEISS VISTHESIA® intra / VISTHESIA²

More comfort through pain relief even in prolonged surgery.

Preoperative topical ampules containing sodium hyaluronate (0.3%) with lidocaine (2%) that coats and hydrates the epithelial cells supporting clear vision into the eye.

Intracameral viscous-cohesive OVD

  • Containing sodium hyaluronate in a concentration of 1% and 1.5%, both with lidocaine (1%)
  • Effective space creation and maintenance in the anterior chamber
  • Ensuring even dispersion of lidocaine throughout the eye to all tissues
  • Providing endothelial protection3 and pupil dilation4
  • 2-in-1 solution saving time and preparation steps, since a separate intracameral anesthetic is not required

ZEISS COMBIVISC®

The perfect match of two OVDs for the entire surgery

Providing the optimal combination of a viscous-cohesive and a medium-viscosity dispersive OVD in two separate syringes. Giving you the space and protection you need in standard and complex cases – with fast and easy removal.

Cohesive part (incl. Z-HYALIN®plus)

  • Highly effective for space creation and maintenance in the anterior chamber5
  • Good capsular bag inflation
  • Optimal chamber retention
  • Ease of injection5
  • Fast and easy removal6

Dispersive part (incl. Z-HYALCOAT®)

  • Reliable protection of the endothelium during various surgical maneuvers
  • Great space partition
  • Excellent optical clarity7
  • Ease of injection
  • Short aspiration time6

ZEISS TWINVISC®

Two OVDs, one device for each stage of the surgery

Combining a medium-viscosity dispersive and a viscous-cohesive viscoelastic in one syringe separated by an innovative bypass stopper system for a planned sequential injection. Providing an easy and unique approach to the soft-shell-technique.8

  • Reliable protection of the endothelium and other tissues during various surgical maneuvers
  • Highly effective space creation and maintenance in the anterior chamber during IOL implantation8
  • Great retention during phacoemulsification9
  • Excellent optical clarity9
  • Ease of injection
  • Fast and easy removal9

ZEISS Z-CELCOAT®

Low-viscosity dispersive OVD - providing protection in surgery

  • Protection of the endothelium through coated ocular tissues during various surgical maneuvers10
  • Good space partition
  • Well suited as lubricant for intraocular lenses and instruments
  • Available in large volume syringe (2.1 ml)
  • Multipack option (pack of 10 pc)

ZEISS Z-HYALCOAT

Medium-viscosity dispersive OVD - a safeguard in surgery

  • Reliable protection of the endothelium during various surgical maneuvers
  • Great space partition
  • Excellent optical clarity7
  • Short aspiration time6
  • Available in large volume syringe (0.85 ml)
  • Multipack option (pack of 10 pc)
* Not all products are pictured.

ZEISS Z-HYALIN, ZEISS Z-HYALIN plus, ZEISS Z-HYALON*

Viscous-cohesive OVDs – with versatility in space maintenance

  • Varying effectiveness of space creation and maintenance in the anterior chamber as a result of increases in molecular weight
  • Good to very good capsular bag inflation
  • Optimal chamber retention
  • Smooth injection
  • Fast and easy removal
  • Available in high volume syringes (1 ml, 1 ml, 0.55 ml / 0.85 ml)
  • Multipack option (pack of 10 pc)

ZEISS Z-HYALON® plus

Super-viscous cohesive OVD - with excellent performance in space maintenance even in challenging surgery cases

  • Excellent space creation and maintenance due to super high molecular weight
  • Very good capsular bag inflation
  • Optimal optical clarity
  • Very easy injection
  • Faster and easier removal

ZEISS Multipack

Your favorite box of ten

ZEISS OVDs available in 10 syringe multipacks:

  • COMBIVISC (pack of 5 pairs)
  • Z-CELCOAT
  • Z-HYALCOAT
  • Z-HYALIN
  • Z-HYALIN plus
  • Z-HYALON

Powerful as individual solution – Unstoppable together

The new ZEISS Cataract Workflow

By connecting devices, data and applications, the ZEISS portfolio enables a seamless integration from office to OR and back.

Product comparison

  • Classification
    Single pack content
    Multipack content
    Origin
    Volume (ml)
    Substance
    Concentration I (%)
    Concentration II (mg/ml)
    VISTHESIA 1.0%
    Viscous-cohesive
    1 x intracameral syringe
    Bacterial fermentation
    0.8
    Sodium Hyaluronate
    1.0
    10
    1 x 27 G cannula
    Lidocaine
    1.0
    10
    2 x topical ampules (see below*)
    Hydrochloride
    VISTHESIA 1.5%
    Viscous-cohesive
    1 x intracameral syringe
    Bacterial fermentation
    0.8
    Sodium Hyaluronate
    1.5
    15
    1 x 27 G cannula
    Lidocaine
    1.0
    10
    2 x topical ampules (see below*)
    Hydrochloride
    *VISTHESIA topical ampule11
    n/a
    2 x topical ampules
    Bacterial fermentation
    2 x 0.3
    Sodium Hyaluronate
    2 x 0.3
    2 x 3
    Lidocaine
    2.0
    20
    Hydrochloride
    VISTHESIA 1.0% intra12
    Viscous-cohesive
    1 x intracameral syringe
    Bacterial fermentation
    0.8
    Sodium Hyaluronate
    1.0
    10
    1 x 27 G cannula
    Lidocaine
    1.0
    10
    Hydrochloride
    VISTHESIA 1.5% intra12
    Viscous-cohesive
    1 x intracameral syringe
    Bacterial fermentation
    0.8
    Sodium Hyaluronate
    1.5
    15
    1 x 27 G cannula
    Lidocaine
    1.0
    10
    Hydrochloride

    All OVDs are phthalate free and have a pH range between 6.8 and 7.6.
    The shelf life for all OVDs is 3 years except for TWINVISC, which has a shelf life of 2 years

  • Classification
    Single pack content
    Multipack content
    Origin
    Volume (ml)
    Substance
    Concentration I (%)
    Concentration II (mg/ml)
    COMBIVISC
    Viscous-cohesive
    1 x intracameral syringe
    5 x intracameral syringes
    Bacterial fermentation
    1.0
    Sodium Hyaluronate
    1.5
    15
    1 x 25 G cannulas
    5 x 25 G cannulas
    Medium-viscosity dispersive
    1 x intracameral syringes
    5 x intracameral syringes
    Bacterial fermentation
    0.85
    Sodium Hyaluronate
    3.0
    30
    1 x 25 G cannula
    5 x 25 G cannulas
    TWINVISC
    Medium-viscosity dispersive
    1 x two-chamber intracameral syringe
    -
    Bacterial fermentation
    0.7
    Sodium Hyaluronate
    2.2
    22
    1 x 25 G cannula
    Viscous-cohesive
    1 x two-chamber intracameral syringe
    -
    Bacterial fermentation
    0.7
    Sodium Hyaluronate
    1.0
    10
    1 x 25 G cannula

    All OVDs are phthalate free and have a pH range between 6.8 and 7.6.
    The shelf life for all OVDs is 3 years except for TWINVISC, which has a shelf life of 2 years

  • Classification
    Single pack content
    Multipack content
    Origin
    Volume (ml)
    Substance
    Concentration I (%)
    Concentration II (mg/ml)
    Z-CELCOAT
    Low-viscosity dispersive
    1 x intracameral syringe
    10 x intracameral syringes
    Botanical
    2.1
    Hydroxypropyl-methylcellulose
    2.0
    20
    1 x 23 G cannula
    10 x 23 G cannulas
    Z-HYALCOAT
    Medium-viscosity dispersive
    1 x intracameral syringe
    10 x intracameral syringes
    Bacterial fermentation
    0.85
    Sodium Hyaluronate
    3.0
    30
    1 x 25 G cannula
    10 x 25 G cannulas

    All OVDs are phthalate free and have a pH range between 6.8 and 7.6.
    The shelf life for all OVDs is 3 years except for TWINVISC, which has a shelf life of 2 years

  • Classification
    Single pack content
    Multipack content
    Origin
    Volume (ml)
    Substance
    Concentration I (%)
    Concentration II (mg/ml)
    Z-HYALIN
    Viscous-cohesive
    1 x intracameral syringe
    10 x intracameral syringes
    Bacterial fermentation
    1.0
    Sodium Hyaluronate
    1.0
    10
    1 x 27 G cannula
    10 x 27 G cannulas
    Z-HYALIN plus
    Viscous-cohesive
    1 x intracameral syringe
    10 x intracameral syringes
    Bacterial fermentation
    1.0
    Sodium Hyaluronate
    1.5
    15
    1 x 27 G cannula
    10 x 27 G cannulas
    Z-HYALON
    Viscous-cohesive

    10 x intracameral syringes

    10 x intracameral syringes

    Rooster comb
    0.55 or 0.85
    Sodium Hyaluronate
    1.0
    10

    10 x 27 G cannulas

    10 x 27 G cannulas

    Z-HYALON plus
    Super-viscous cohesive
    1 x intracameral syringe
    -
    Rooster comb

    0.55

    Sodium Hyaluronate
    1.4
    14
    1 x 27 G cannula

    All OVDs are phthalate free and have a pH range between 6.8 and 7.6.
    The shelf life for all OVDs is 3 years except for TWINVISC, which has a shelf life of 2 years

Technical information

Molecular weight (megadalton)13
Zero-shear viscosity (Pa s)14
CDI
Pseudo-plasticity
Osmolality (mOsmol/kg)
Storage temperature (°C)
Overall comforter
VISTHESIA 1.0%
2.9
72
39
75
280–330
2–8
VISTHESIA 1.5%
2.9
295
44
133
280–330
2–8
VISTHESIA Topical ampule11
2.9
1
n/a
n/a
270–320
2–8
VISTHESIA 1.0% intra12
2.9
72
39
75
280–330
2–8
VISTHESIA 1.5% intra12
2.9
295
44
133
280–330
2–8
Multitalents
COMBIVISC
Cohesive 2.9
Cohesive 295
Cohesive 44
Cohesive 133
Cohesive 300–360
2–8
Dispersive 1.0
Dispersive 47
Dispersive 39
Dispersive 10
Dispersive 300–360
2–8
TWINVISC
Dispersive 1.0
Dispersive 14
Dispersive 26
Dispersive 8
Dispersive 300–360
2–8
Cohesive 2.1
Cohesive 18
Cohesive 36
Cohesive 18
Cohesive 300–350
2–8
Protecting layers
Z– CELCOAT
0.086
5
28
16
280–320
2-30
Z– HYALCOAT
1.0
47
18
10
300–360
2–8
Space creators
Z– HYALIN
2.9
72
39
75
300–350
2–8
Z–HYALIN plus
2.9
295
44
133
300–360
2–8
Z– HYALON
5.0
1.000

>30

389

310

2-8

Z–HYALON plus
5.0

3.300

>30

549

320

2-8

Downloads

    • ZEISS OVD portfolio

      The power of choice at every step (EU version)

      Pages: 7
      File size: 2 MB
    • ZEISS OVD portfolio

      The power of choice at every step (Non-EU version)

      Pages: 7
      File size: 2 MB
    • ZEISS IOL & OVD portfolio

      Technical specifications

      Pages: 7
      File size: 2 MB
    • ZEISS VISTHESIA / ZEISS VISTHESIA intra

      Technical specifications

      Pages: 2
      File size: 160 KB
    • ZEISS COMBIVISC

      Technical specifications

      Pages: 2
      File size: 176 KB
    • ZEISS TWINVISC

      Technical specifications

      Pages: 2
      File size: 186 KB
    • ZEISS Z-CELCOAT

      Technical specifications

      Pages: 2
      File size: 109 KB
    • ZEISS Z-HYALCOAT

      Technical specifications

      Pages: 2
      File size: 173 KB
    • ZEISS Z-HYALIN / ZEISS Z-HYALIN plus

      Technical specifications

      Pages: 2
      File size: 201 KB
    • ZEISS Z-HYALON / ZEISS Z-HYALON plus

      Technical specifications

      Pages: 2
      File size: 128 KB
    • Three-step-guide and users' experience

      ZEISS VISTHESIA, ZEISS VISTHESIA intra

      Pages: 2
      File size: 897 KB
    • ZEISS COMBIVISC

      The perfect match of two OVDs for the entire ophthalmic surgery

      Pages: 4
      File size: 2 MB
    • Surgeons share their experience

      ZEISS TWINVISC

      Pages: 2
      File size: 457 KB
    • Surgeons share their experience

      ZEISS Z-HYALIN plus

      Pages: 2
      File size: 426 KB
  • 1

    Except: Z-HYALON, Z-HYALON plus, Z-CELCOAT

  • 2

    VISTHESIA 1.0% and VISTHESIA 1.5% are not for sale in the UK or Portugal

  • 3

    F. Poyales-Galan, G. Pirazzoli: Clinical Evaluation of Endothelial Cell Decrease with VISTHESIA In: Phacoemulsification Surgery. JCRS Vol. 31, Nov. 2005

  • 4

    S. K. Pandey et al.: Evaluation of the cataractgenic effect of viscoanesthetic solutions on the rabbit crystalline lens. JCRS Vol. 31, July 2005

  • 5

    Harry Domack: Z-HYALIN Plus: A Versatile Cohesive Agent. Cataract & Refractive Surgery Today, Europe, July/August 2011

  • 6

    S. A. Arshinoff, M Jafari: New classification of ophthalmic viscosurgical devices. JCRS Vol. 31, Nov. 2005

  • 7

    W. W. Hütz et al.: Comparison of viscoelastic substances used in phacoemulsification. JCRS Vol. 22, Sept. 1996

  • 8

    ZEISS: TWINVISC – Two OVDs, one syringe, a unique concept (User testimonial by S. Arshinoff), 2011

  • 9

    G. U. Auffahrt et al.: Comparison of the performance and safety of 2 ophthalmic viscosurgical devices in cataract surgery. JCRS Vol. 43, Jan. 2017

  • 10

    A. D. Steele, V. Andrews: Methylcellulose for endothelial cell protection. Australian and New Zealand Journal of Ophthalmology Vol. 16, 1988

  • 11

    Not available individually; only available with VISTHESIA 1.0% or 1.5%

  • 12

    VISTHESIA intra version does not contain 2 topical ampules

  • 13

    Megadalton = 1 million Dalton

  • 14

    1Pa s = 1000 mPa s