ZEISS ReLEx SMILE: Creating a new future for your practice
Transforming your practice with technology that's easy on the eyes. ZEISS ReLEx SMILE


  • Product Information
    ReLEx – Laser vision correction beyond LASIK

    ReLEx SMILE from ZEISS

    The first minimally invasive laser vision correction solution

    ReLEx® SMILE from ZEISS is the first and only small incision lenticule extraction (SMILE) laser vision correction solution currently available. ZEISS is the only company to provide a way for treating patients with this minimally invasive procedure. Now it is time. Provide your patients a new laser vision correction option and create a new future for your practice with ReLEx SMILE.


    Note: This diagram is based on an optical zone of 6.5 mm.

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    Explore the advantages of ReLEx SMILE from ZEISS

    Minimally invasive – With ReLEx SMILE, a lenticule and a small incision of < 6 mm is created inside the intact cornea, enabling an 80% smaller side-cut and 30% smaller cap cut, as compared to a LASIK flap.

    First SMILE solution – With ReLEx SMILE, ZEISS is at the forefront of laser vision correction with a procedure that is redefining refractive laser surgery as we know it.

    ReLEx SMILE indication range for myopia and astigmatism:

    • -1.00 D to -8.00 D, with ≤ -0.50 D cylinder and MRSE -8.25 D, in the eye to be treated in patients who are 22 years of age or older with documentation of stable manifest refraction over the past year.
  • Treatment Steps

    Refractive correction with ReLEx SMILE from ZEISS

    ZEISS ReLEx® SMILE utilizes the high-precision VisuMax® femtosecond laser from ZEISS to create a lenticule inside the cornea and access incision in a single treatment step.

    SMILE with VisuMax

    SMILE with VisuMax

    A refractive lenticule and small incision are created inside the intact cornea – all in one step.

    SMILE with VisuMax

    The lenticule is subsequently removed through this small incision, leaving the remainder of the superficial cornea intact.

    SMILE with VisuMax

    Removing the lenticule changes the shape of the cornea, thereby achieving the desired refractive correction.

  • Benefits
    Relex 2x doctor using relex

    Up to 80 % smaller side-cut

    Femto-LASIK requires a side-cut of roughly 20 mm. With ZEISS ReLEx SMILE,
    a small incision of < 6 mm is sufficient.


    Up to 30 % smaller cap incision area
    The lamellar incision area is roughly 1/3 smaller compared to Femto-LASIK.


    Greater integrity of the upper corneal layers
    With SMILE, the majority of the upper corneal layers remains intact. This offers the potential for more biomechanical preservation and stability.


    Relex 2x relex

    With ZEISS ReLEx SMILE, the entire procedure is performed with the groundbreaking femtosecond laser technology of the VisuMax® femtosecond laser. As a result, there is no need for complex nomograms or fluence tests.


    Accuracy and dependability every time
    ZEISS ReLEx SMILE embodies precision, predictability, reproducibility and perfection. Using the VisuMax, it creates a precalculated lenticule and incision with utmost accuracy and dependability.


    With ZEISS ReLEx SMILE, the entire correction is performed as a single-step: on one laser, with one treatment plan and one laser process.


    Lenticule and access in one
    What also makes it a single-step solution is that the lenticule inside the intact cornea as well as the access incision are created in one treatment step.


    Enhanced patient experience
    Incorporating superior ZEISS technology, ZEISS ReLEx SMILE enhances the treatment experience for patients with the outstanding cutting precision, exceptional speed and gentle treatment approach of the ZEISS VisuMax.

  • Clinical Data

    ReLEx SMILE – clinical results


    ReLEx smile - clinical results

    The clinical study reports on the results of the ReLEx SMILE procedure for the correction of myopia (6 month results).

    Background and method

    • 328 eyes were analyzed and evaluated in five study centers
    • All the eyes had a best-corrected visual acuity of 20/20 or better before the operation


    • Consistent results with outstanding predictability
    • Very close to target refraction
    • Valid across entire range of correction, from low to high-level myopia


    88% of all patients with a preoperative best-corrected visual acuity of 20/20 or better achieved uncorrected visual acuity of 20/20 or better after surgery.


    Impressive stability of the refractive correction (MRSE)


    • 98.5% of all patients achieved target refraction within the typical “satisfaction zone” (± 1.00 D)
    • 93% of all patients achieved target refraction with a precision of ± 0.50 D

  • Media Library

    VisuMax femtosecond system

    Defining the pulse rate in refractive surgery

    Page(s): 7
    File size: 973 kB

    ReLEx SMILE from ZEISS

    The first minimally invasive laser vision correction solution

    Page(s): 4
    File size: 412 kB

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    ReLEx SMILE Trailer

    Type of file: mp4
    Filesize: 26.9 MB


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    ReLEx SMILE with VisuMax

    Type of file: mp4
    Filesize: 8.49 MB


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