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  • Product Information
    ReLEx – Laser vision correction beyond LASIK

    Minimally invasive Laser Vision Correction

    With ReLEx® from SMILE®, a lenticule and a small incision of 60 or 90 degrees is created inside the intact cornea, enabling an 80% smaller side-cut and 30% smaller cap cut, as compared to a LASIK flap.

    Minimally invasive surgery

    Explore the advantage of ReLEx SMILE from ZEISS

    • Minimally invasive surgery. 
      With SMILE, a lenticule and a small incision of 60 or 90 degrees is created inside the thus transecting fewer corneal nerves. The corneal nerve plexus is responsible for corneal sensation and maintenance of a healthy tear film. Also, the small incision associated with SMILE results is less disruption to the anterior corneal stroma compared to LASIK or PRK. The anterior stroma is thought to be responsible for playing an important roll in the biomechanical integrity of the cornea.
    • Single step. 
      With SMILE, the entire correction is performed as a single-step: one laser, one treatment plan and one laser process.
    • All-Femto. 
      Performed on a VisuMax® femtosecond laser from ZEISS, high precision, proven outcomes, predictability and ease of use are what SMILE stands for.


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    ReLEx SMILE indication range for myopia and astigmatism

    • Sphere: -1.00 D to -10.00 D
    • Cylinder: -0.75 D to -3.00 D
    • MRSE up to -10.00 D
  • Treatment Steps
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    Treatment steps – Fast and gentle

    ReLEx® SMILE® from ZEISS utilizes the high-precision VisuMax® femtosecond laser from ZEISS to create a lenticule inside the cornea and access incision in a single treatment step. Its outstanding cutting precision, exceptional speed and gentle treatment approach make it an ideal platform for advanced corneal surgery applications such as SMILE.

    SMILE with VisuMax

    SMILE with VisuMax

    A refractive lenticule and small incision are created inside the intact cornea – all in one step.

    SMILE with VisuMax

    The lenticule is subsequently removed through this small incision, leaving the remainder of the superficial cornea intact.

    SMILE with VisuMax

    Removing the lenticule changes the shape of the cornea, thereby achieving the desired refractive correction.

  • Services
    ZEISS Customer Care

    ZEISS Customer Care

    Service agreements to protect your investment

    Every facet of Customer Care at ZEISS is designed to protect your investment in your equipment. Whether it is a high-end surgical microscope, an ophthalmic laser, or diagnostic equipment, we provide timely, responsive services through a national network of highly skilled technicians. Our dedication to providing the highest quality of customer care is reflected by the fact that our customers consistently rank us superior in terms of their satisfaction with our performance.

    More about customer care
  • Benefits

    Benefits of ReLEx SMILE

    SMILE® is a minimally invasive Laser Vision Correction procedure for myopia and astigmatism correction. During SMILE eye surgery, a lenticule is created inside the cornea using the ZEISS VisuMax femtosecond laser. Subsequently, the lenticule is extracted through a small incision, thereby achieving the desired vision correction.

    Minimally invasive Laser Vision Correction

    To achieve the refractive correction, with ZEISS ReLEx SMILE a small incision of 60 or 90 degrees is sufficient to remove the lenticule from the intrastromal layer of the cornea, thus preserving the corneal structure.

    Great integrity of the upper corneal layers

    With SMILE, the majority of the upper corneal layers remains intact. The anterior stroma of the upper corneal layers is thought to be responsible for playing an important roll in the biomechanical integrity of the cornea.

    Easy postoperative management

    The excellent predictability of the refractive outcome leads to a low percentage of retreatments. Furthermore ReLEx SMILE reduces the incidence of infection and epithelial ingrowth, cumulating in overall fast healing.


    ZEISS ReLEx SMILE embodies precision, predictability, reproducibility and perfection. Using the VisuMax femtosecond laser, it creates a precalculated lenticule and incision with utmost accuracy and dependability.


    ReLEx SMILE saves time and increases comfort for surgeons and patients alike by performing the refractive correction with one treatment plan and on a single laser. The lenticule inside the cornea and the access incision are created in a single step.

  • Clinical Data

    ReLEx SMILE – clinical results


    ReLEx smile - clinical results

    The clinical study reports on the results of the ReLEx SMILE procedure for the correction of spherocylindrical myopia.1

    Background and method

    • 357 eyes were analyzed and evaluated in five study centers
    • All the eyes had a best-corrected visual acuity of 20/20 or better before the operation


    • Consistent results with very good predictability
    • Very close to target refraction
    • Valid across entire range of correction, from low to high-level myopia


    • At 6 months, 99% of eyes achieved a UCVA of 20/40 or better.
    • At 6 months, 84% of eye had a UCVA of 20/20 or better.

    Accuracy of MRSE

    Predictability and accuracy of the MRSE comparable to or better than LASIK (6 months after surgery).

    Accuracy of cylinder correction

    Predictability and accuracy of the cylinder correction 6 months after surgery is comparable or better than LASIK results.
  • Media Library

    VisuMax from ZEISS

    Defining the pulse rate in refractive surgery

    Page(s): 13
    File size: 11,587 kB



    Video Downloads

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    Without pupil tracking and cyclotorsional alignment, how can SMILE be as good as my LASIK treatments?

    Type of file: mp4
    Filesize: 7.1 MB

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    Is SMILE as reliable or predictable as LASIK?

    Type of file: mp4
    Filesize: 3.3 MB

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    ReLEx SMILE with VisuMax

    Type of file: mp4
    Filesize: 6.6 MB

  • 1 Data on file.