Making the revolutionary, routine.

ZEISS AngioPlex OCT Angiography

Transforming your everyday.

ZEISS AngioPlex OCT Angiography

The complete OCT solution for a broad range of patients

AngioPlex® OCT Angiography from ZEISS ushers in a new era in eye care with non-invasive imaging of retinal microvasculature – taking glaucoma and retinal disease management and treatment planning to the next level. By offering comprehensive tools for assessing and analyzing a range of pathologies, ZEISS provides a complete OCT solution.

Make OCT Angiography a reality in your practice.

Integrating OCT Angiography into your practice provides advanced care for your patients and the advanced technology you need to support the demands of today's aging population.

Powered by eyecare's leading clinical OCT platform, CIRRUS™ HD-OCT from ZEISS, AngioPlex enables you to do more—get ultra-clear visualizations of the retina, see a wider field of view, gain expanded insights, track change and build your practice.


Non-invasive, dyeless angiography
Unlike other OCTA technologies, ZEISS AngioPlex enables the visualization of both vascular and structural information from a single, non-invasive scan. Watch the video to understand how it works.

OCTA for Diabetic Retinopathy, Age-related Macular Degeneration, Glaucoma & more
OCT Angiography is known to reveal early indicators of many ocular diseases. ZEISS AngioPlex provides the practitioner with advanced imaging of patients suffering from vision loss due to diabetic retinopathy, glaucoma, AMD and other eye conditions.

Diabetic Retinopathy
Diabetic Retinopathy
Age-related Macular Degeneration (AMD)
Age-related Macular Degeneration (AMD)

Fast & Easy
AngioPlex image capture with Single Scan Simplicity and FastTrac™ lets you scan at the highest resolution, minimizing artifacts from blinks and other eye movements, and without sacrificing patient throughput. Watch the video to understand how it works.

Watch the Video Now

Manage your patients longer with CIRRUS HD-OCT with AngioPlex

Manage your patients longer
According to a recent survey*, the majority of AngioPlex users have incorporated OCTA into their disease management protocol—AMD (90%), DR (88%) and diseases of the vasculature (85%). ZEISS AngioPlex is designed to support long-term patient management and guides clinicians on when to intervene or refer.

*Pekelis M, Durbin M, Ge B, “Clinical usage patterns of OCT Angiography,” poster presentation, Sonoma Eye 2018, Sonoma, CA, USA


Get big-picture insights in a single view

The AngioPlex Montage is very useful in allowing me to quickly identify the presence of neovascularization (both NVD and NVE) in proliferative diabetic retinopathy without the use of fluorescein dye.

Scott S. Lee¹, MD, East Bay Retina, USA

Capture widefield OCTA images with AngioPlex Montage

AngioPlex Montage from ZEISS delivers widefield OCTA with up to a 50° field of view, helping clinicians visualize vasculature aiding in the diagnosis of diseases affecting the macula and peripheral retina such as diabetic retinopathy and branch retinal vein occlusion. Detail-rich images enable quick and comprehensive vascular assessment and can be an excellent tool for patient education.

Scroll through the gallery to see more images.

Widefield OCT Angiography with ZEISS AngioPlex
14x14 mm AngioPlex Montage of Branch Retinal Vein Occlusion showing ischemia with collateral vessels.
Widefield OCT Angiography with ZEISS AngioPlex
Color-depth encoded 14x14 mm AngioPlex Montage.
Widefield OCT Angiography with ZEISS AngioPlex
10x14 mm AngioPlex Montage of Proliferative Diabetic Retinopathy.

Learn how to manage your patients with AngioPlex OCT Angiography

Despite being a relatively new technology, clinicians are beginning to see and understand how integrating OCTA can enhance patient and disease management. To see this for yourself, download the PDF below.

Reveal more with automated segmentation

Automated segmentation on ZEISS AngioPlex offers clinicians several preset segmentation capabilities that isolate layers deep into the retina and choroid with just a click. This is especially useful for a comprehensive evaluation of age-related macular degeneration (AMD) and identification of conversion from dry to wet AMD.

Available presets on AngioPlex: Vitreoretinal interface (VRI), Superficial, Deep, Avascular, RPE to RPE fit (new), Sub-RPE Retina, Choriocapillaries, Choroid, Retina and Outer Retina to Choriocapillaris (new)

Scroll through the images to see how automated segmentation helps disease management.

Would you like to learn more on OCTA segmentation for AMD management? Watch the video series below and learn from the experts.
Follow dry to wet AMD conversion with ZEISS AngioPlex

VRI (Vitreoretinal Interface)
Observe neovascularization elsewhere (NVE) associated with proliferative diabetic retinopathy (PDR). 

Follow dry to wet AMD conversion with ZEISS AngioPlex

ORCC (Outer Retina to Choriocapillaris)
More easily visualize classic or occult choroidal neovascularization (CNV).

Follow dry to wet AMD conversion with ZEISS AngioPlex

RPE to RPE fit
Highlights disruptions to the retinal pigment epithelium (RPE) layer, and can provide improved visualization of CNV.  

Freeform tool
Circle tool
Freeform tool

AngioPlex manual measurement tools

The user can manually measure regions of interest and compare them over time using:

  • The Freeform tool which measures area and perimeter
  • The Circle tool which measures diameter and area
  • The Caliper tool which measures distance in milimeters

Now track vascular changes in glaucoma with OCT Angiography.

AngioPlex for ONH allows us to view the radial peripapillary capillaries – making it possible for us to detect focal glaucomatous perfusion defects.

Grace Richter², MD, MPH, USC Roski Eye Institute, USA



The ultimate in service

Do you rely on high system availability? If your answer is yes, then consider ZEISS OPTIME service agreements, which are designed to ensure the readiness of your medical equipment at all times.

Resources & Downloads

AngioPlex from ZEISS

The complete OCT Angiography solution

10 Page(s)
File size: 7,047 kB


OCTA Video Series

Experts speak on AngioPlex

More ZEISS OCTA Content on Demand

Educational videos and clinical case images

Explore ZEISS OCTA Access on EyeTube

Check out OCTA on EyeTube!
Hear experts speak on the value of integrating OCTA into your practice.

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Download the ZEISS Clinical Image Library on your iPad now!

Download our Clinical Image Library app on iTunes!
This iPad app gives you access to a large collection of OCTA cases and images.

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 1,2 The statements of the healthcare professionals reflect only their personal opinions and experiences and do not necessarily reflect the opinions of any institution with whom they are affiliated. The healthcare professionals have no contractual or other financial relationship with Carl Zeiss Meditec AG or Carl Zeiss Meditec, Inc., and received no financial support for these statements.