Non-destructive Imaging Using X-rays
Visualizing Structure of Life Science Specimens
Understanding physiological structures is at the core of many research questions for life scientists working in musculoskeletal research, neuroscience, developmental biology, zoology, cancer research, entomology, and plant sciences. You may be seeking larger volumes of structural information and would prefer to avoid physical sectioning. ZEISS X-ray imaging systems provide high-contrast, high-resolution 3D imaging of your delicate biological samples including mineralized and soft tissues, individual organs and organoids, plant tissues and more. All can be studied histologically, without dissection, inside the specimen down to a cellular level.
Sub-micron 3D Imaging of Intact Samples
X-ray microscopes contain dedicated optical lenses to provide high resolution imaging, even in larger specimens. The ZEISS Xradia Versa X-ray microscope images samples ranging in size from millimeters to centimeters with sub-micrometer resolution. Whether you are investigating histology in whole embryos or tissue plugs, exploring structure in large samples such as bone, expanding your 3D view in delicate specimens like brain and other soft tissues or imaging the internal structures of plants or seeds, you can achieve high resolution and high contrast imaging without cutting your sample. Capture a large field of view to locate structures of particular interest and then zoom in with a higher magnification lens to explore these regions at greater resolution.
Rapid Structural Imaging for Increased Productivity
Classical microCT is a powerful approach for the assessment of internal 3D structure when the priority is acquisition speed rather than highest possible resolution. The ZEISS Xradia Context microCT generates high-contrast images from samples ranging from millimeters to tens of centimeters in size and shares the stability and image quality optimizations found with all ZEISS Xradia X-ray imaging platforms.
This approach is perfect for rapid exploration of internal structure of samples as diverse as organs, bones, soft tissues, plants and small animal models, without the need for dissection.
Extending the Reach of Non-destructive Imaging to the Nanoscale
With resolution down to 50 nm, the ZEISS Xradia Ultra X-ray microscope provides non-destructive imaging possibilities at resolutions otherwise unachievable outside the synchrotron. With both absorption and Zernike phase contrast acquisition modes, you can image a diverse range of specimens using both stained and unstained sample preparation protocols. Whether your goal is studying cellular and subcellular structure, looking at nanoparticle uptake, biomaterial nanostructure or non-destructively exploring your specimen with nano resolution, ZEISS Xradia Ultra provides unique possibilities.
* The images shown on this page represent research content. ZEISS explicitly excludes the possibility of making a diagnosis or recommending treatment for possibly affected patients on the basis of the information generated with an Axioscan 7 slide scanner.