Automated microscope for gentle and fast confocal 4D imaging

Enhancing ZEISS Celldiscoverer 7 with ZEISS LSM 900 for optical sectioning

Jena/Germany | 11 April 2019 | ZEISS Research Microscopy Solutions

The proven ZEISS Celldiscoverer 7 is a fully integrated high-end imaging system with various incubation and detection options. It combines the easy-to-use automation of a boxed microscope with the image quality and flexibility of a classic inverted research microscope. To get better data from three-dimensional samples, it is now possible to add ZEISS LSM 900 with Airyscan 2 for confocal imaging.

ZEISS Celldiscoverer 7 with LSM 900
Whether working with 2D or 3D cell cultures, tissue sections or small model organisms, users can now enhance ZEISS Celldiscoverer 7 with ZEISS LSM 900 for optical sectioning to get more information from their samples.

Connecting widefield and confocal – the best of both worlds

Life sciences research often calls for optical sectioning to image samples with best possible contrast and resolution. By adding ZEISS LSM 900 with Airyscan 2 to ZEISS Celldiscoverer 7, users get the ease-of-use and automation from a fully integrated microscope platform and the superb confocal image quality and flexibility of the ZEISS LSM 9 family with Airyscan 2. The new Multiplex mode allows the user to perform superresolution 3D imaging with up to 1.5x higher resolution. Additionally, researchers can easily separate multiple labels with spectral imaging.

A flexible, integrated microscope

ZEISS Celldiscoverer 7 simplifies the laboratory setup and makes work more comfortable. All components are optimized for hassle-free automated imaging. New users and multi-user facilities especially enjoy the in-built automation and usability features when setting up complex experiments. Users can expect better data in shorter times, with less training and maintenance. As the user’s requirements grow, they can expand ZEISS Celldiscoverer 7 with confocal technology, external cameras, deconvolution, and additional environmental control – whatever they need for the challenge of live cell observation.

Primary lung fibroblasts
Primary lung fibroblasts stained with mitotracker red (mitochondria) and a DNA marker (nuclei). ZEISS Celldiscoverer 7 with LSM 900 seamlessly combines two imaging modes. Fluorescent channels were acquired in confocal mode using highly sensitive GaAsP detectors while the Phase Gradient Contrast is acquired with a camera. Sample courtesy of S. Gawrzak and M. Jechlinger, EMBL, Heidelberg, Germany. A timelapse of 2.5 h was acquired using a 40x magnification with a numerical aperture of 0.95: https://zeiss.ly/lung-fibroblasts
Press Contact

Vybhav Sinha
ZEISS Research Microscopy Solutions
Phone: +49 3641 64-3949
vybhav .sinha @zeiss .com

About ZEISS

ZEISS is an internationally leading technology enterprise operating in the fields of optics and optoelectronics. In the previous fiscal year, the ZEISS Group generated annual revenue totaling more than 5.8 billion euros in its four segments Industrial Quality & Research, Medical Technology, Consumer Markets and Semiconductor Manufacturing Technology (status: 30 September 2018).

For its customers, ZEISS develops, produces and distributes highly innovative solutions for industrial metrology and quality assurance, microscopy solutions for the life sciences and materials research, and medical technology solutions for diagnostics and treatment in ophthalmology and microsurgery. The name ZEISS is also synonymous with the world's leading lithography optics, which are used by the chip industry to manufacture semiconductor components. There is global demand for trendsetting ZEISS brand products such as eyeglass lenses, camera lenses and binoculars.

With a portfolio aligned with future growth areas like digitalization, healthcare and Smart Production and a strong brand, ZEISS is shaping the future far beyond the optics and optoelectronics industries. The company's significant, sustainable investments in research and development lay the foundation for the success and continued expansion of ZEISS' technology and market leadership.

With approximately 30,000 employees, ZEISS is active globally in almost 50 countries with around 60 of its own sales and service companies, more than 30 production sites and around 25 development sites. Founded in 1846 in Jena, the company is headquartered in Oberkochen, Germany. The Carl Zeiss Foundation, one of the largest foundations in Germany committed to the promotion of science, is the sole owner of the holding company, Carl Zeiss AG.

Further information at www.zeiss.com

ZEISS Research Microscopy Solutions

ZEISS Research Microscopy Solutions is the world's only one-stop manufacturer of light, electron, X-ray and ion microscope systems and offers solutions for correlative microscopy. The portfolio comprises of products and services for life sciences, materials and industrial research, as well as education and clinical practice. The unit is headquartered in Jena. Additional production and development sites are located in Oberkochen, Göttingen and Munich, as well as in Cambridge in the UK, and in Peabody, MA and Pleasanton, CA in the USA. ZEISS Research Microscopy Solutions is part of the Industrial Quality & Research segment.

Press Contact

Vybhav Sinha
ZEISS Research Microscopy Solutions
Phone: +49 3641 64-3949
vybhav .sinha @zeiss .com

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Press Photos
ZEISS Celldiscoverer 7 with LSM 900
Primary lung fibroblasts
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