ZEISS at FOM 2017

Microscopy Events

ZEISS at Focus on Microscopy 2017

April 9 - 12, Booth #38, 39, 40 - Bordeaux, France

We look forward meeting you at Focus on Microscopy 2017 in Bordeaux!

Hear about latest innovations and developments in microscopy and their application in biology, medicine, and materials science. Test-drive Celldiscoverer 7, the new reliable research platform that offers a unique combination of automation features in life science research. Learn how your life science research benefits from Airyscan, the revolutionary confocal detection concept, and discuss your applications for the unique ZEISS MultiSEM technology with our experts.

In our Lunch & Learn talks you will hear how researchers utilize ZEISS microscope technology to push the limits of science.

ZEISS Celldiscoverer 7

Your Automated Platform for Live Cell Imaging


Celldiscoverer 7 combines the user-friendly automation features of a boxed microscope with the image quality and flexibility of a classic inverted research microscope. 

ZEISS LSM 880 with Airyscan

Your New Standard for Fast and Gentle Confocal Imaging


Airyscan is a 32 channel GaAsP-PMT area detector, positioned at the pinhole-plane of an LSM. Using Airyscan, additional light and spatial information is collected beyond that of a typical LSM image.

ZEISS MultiSEM

The World’s Fastest Scanning Electron Microscopes


Revolutionize the Speed of Electron Microscopy and unleash the acquisition speed of up to 91 parallel electron beams. 

ZEISS EVENTS AT FOM

Lunch & Learn – Register on our Booth!

Mon 10th & Tues 11th, 1pm, Room E2

ZEISS LSM 880 with Airyscan Fast – Your New Standard for Fast and Gentle Confocal Imaging
Dr. Uros Krzic, ZEISS Microscopy

The LSM 880 with Airyscan is the first confocal microscope that does not require a light rejecting pinhole to obtain high-contrast optical sections of thick specimens. The pinhole is replaced with a patented array detector that, unlike a pinhole, generates optical sections without wasting precious light. Airyscan images therefore demonstrate resolution and signal-to-noise superior to standard confocal microscopes. Moreover, in combination with an innovative specimen illumination mode, Airyscan in Fast Mode allows LSM 880 to operate at very high framerates that were a traditional domain of resonant scanner confocal microscopes, but with superior sensitivity and resolution. LSM 880 with Airyscan, the only microscope of the kind on the market, will continue to serve as an innovation platform for development of such advanced laser-scanning imaging methods that are bound to appear in the coming years.
In this workshop technical details of Airyscan super-resolution and Fast mode imaging will be explained, followed by a presentation by an Airyscan user about how this innovative technology enabled his novel research.
 

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Airyscanning Approaches to Characterize Apoptotic Cell Forces during Epithelium Folding
Emmanuel Martin, Center for Integrative Biology, Toulouse, France

Tissue morphogenesis is essential for metazoan development, and some morphogenetic processes involve apoptosis. In this context, apoptosis was initially viewed as passive cell elimination, having no impact on the surrounding tissue. However, our recent study revealed that, unexpectedly, apoptotic cells generate a force that propagates around them, modifying tissue tension and cell shape, during the morphogenesis of the leg joint formation in Drosophila. Moreover, we discovered that this force is generated by the formation of an acto-myosin apico-basal cable inside the apoptotic cell, after caspase induction. Nevertheless, little is known about this cable and the tissue remodeling induced by this force. Recent technical breakthrough should allow us to further characterize the dynamics of apoptotic force generation.

In this project, we take advantage of Airyscan technology – stretching the limits of the 3D spatial resolution in living sample and improving the signal-to-noise ratio – to characterize better the structure and the dynamics of the actin-myosin cable in the apoptotic cells. Recent data reveal the particular dynamics and distribution of Myosin II along the apico-basal cable formed in apoptotic cells. Furthermore, this technique allow us to follow force transmission in the surrounding tissue through Myosin II and apical junction motion with a high temporal resolution.

 

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