Celldiscoverer 7 – Your Automated Microscope for Live Cell Imaging

• Celldiscoverer 7 is a fully integrated high-end automated live cell imaging system. Tailor the system to your applications with various incubation and detection options.
  
• Go for fast, sensitive sCMOS or EMCCD cameras when performing demanding live cell experiments and rapid time lapse recordings. For screening applications with high throughput, choose a high dynamic range camera with a large field of view.
  
• Add LSM 900 with Airyscan 2 to get better data from three-dimensional samples.
  

• A hardware-based focus finds and keeps the focus automatically after detecting the thickness and optical properties of the sample carrier for demanding long-term, time-lapse imaging.
• Autocorr objectives correct spherical aberrations to deliver crisp contrast and high resolution.
• The automated microscope Celldiscoverer 7 provides a range of integrated incubation options to create the right environment for your living cells.

• Automatic calibration routines ensure reproducible results in live cell imaging.
  
• With barcode recognition you can identify your sample, sample carrier and even the type of experiment.
• If you don‘t work with barcodes, an automatic preview scan will identify the sample carrier and calibrate it.

Life happens in 3D – and your research often calls for optical sectioning to image your living samples with best possible contrast and resolution. Now you can add LSM 900 with Airyscan 2 to your Celldiscoverer 7. You get the best of both worlds: ease of use and automation from a fully integrated microscope platform and the superb confocal image quality and flexibility of the LSM 9 family with Airyscan 2. You perform superresolution live cell imaging with up to 1.5× resolution improvement. And you easily separate multiple labels with spectral imaging. You can now analyze dynamic processes in living samples with photomanipulation for FRAP, FRET or related techniques. It’s never been easier to precisely connect widefield and confocal images. Fast mixed-mode acquisition simplifies and speeds up your workflow and gives you unique insights into your sample.

In life sciences, cell biology or screening applications, your samples mostly consist of water and / or will be mounted in aqueous solutions. Celldiscoverer 7 combines an outstanding 50x water immersion objective with rapid automated immersion supply and removal. An elastic silicon membrane simultaneously seals the sample chamber to avoid unnecessary airflow while protecting the system from potential liquid spillage. Additionally, Celldiscoverer 7 is automatically monitoring the immersion and adding water, as needed. With this automated microscope you can perform unbiased live cell experiments at 37 °C over several days or carry out extensive scanning processes on multiwell plates.

Use the hardware-based Find Focus function to automatically focus your sample and find your region of interest. Select Definite Focus to maintain the focal position throughout your live cell experiments. Or combine both methods: The automated microscope Celldiscoverer 7 can automatically create focus maps for multiple positions in long-term time-lapse experiments.

Use the advantages of LED-technology for efficient illumination with low phototoxicity, fast switching times and long-term stability. That’s what delivers gentle live cell imaging, increased throughput and reproducible results. The fluorescence excitation unit combines up to seven LEDs for maximum flexibility in the choice of dyes – from deep blue to far-red.