Press Release

ZEISS Xradia 630 Versa introduces resolution performance for expanded research capabilities

Human-centered design and AI-based deep learning extend usability and productivity

28 February 2023

Jena, Germany | 28 February 2023 |  ZEISS Research Microscopy Solutions

ZEISS today introduces the ZEISS Xradia 630 Versa X-ray microscope (XRM) for academic and industrial research. The newest addition to the ZEISS Xradia Versa family breaks resolution performance barriers, delivers an intuitive user experience, and accelerates productivity for all with easy, guided workflows and higher throughput.
With the ZEISS Advanced Reconstruction Toolbox (ART) 3.0, the platform also leverages game-changing artificial intelligence (AI) for reconstruction.
These capabilities combine to enable the study of an unprecedented range of samples in the fields of materials science, battery research, advanced electronics, life science and many more while accommodating the novice to most expert users.

  • ZEISS Xradia 630 Versa is the most fully featured platform in the ZEISS Versa family of 3D X-ray microscopes.

    ZEISS Xradia 630 Versa is the most fully featured platform in the ZEISS Xradia Versa family of 3D X-ray microscopes. In addition to the new NavX user interface, the system comes standard with FPX Flat Panel Display and optionally the 40X-Prime detector for high resolution, high energy imaging.

  • Segmented 3D volume of a polymer electrolyte fuel cell (PEFC) membrane electrode assembly. Gas diffusion layer fiber weaves are visible in green and magenta, microporous layer in blue, catalyst in yellow, and electrolyte membrane in red.

    Segmented 3D volume of a polymer electrolyte fuel cell (PEFC) membrane electrode assembly. Gas diffusion layer fiber weaves are visible in green and magenta, microporous layer in blue, catalyst in yellow, and electrolyte membrane in red.

  • Soft tissue specimens like brain can be imaged using XRM to generate 3D structural maps that provide context for other investigative approaches, such as light microscopy or electron microscopy. The sample is a single slice from a 3D dataset of a mouse brain imaged with the 40X-P objective of the ZEISS Xradia Versa 630 XRM and reconstructed using ZEISS DeepRecon. An inverted LUT has been applied. Sample courtesy of Dr Kevin Boergens, University of Illinois at Chicago, USA.

    Soft tissue specimens like brain can be imaged using XRM to generate 3D structural maps that provide context for other investigative approaches, such as light microscopy or electron microscopy. The sample is a single slice from a 3D dataset of a mouse brain imaged
    with the 40X-P objective of the ZEISS Xradia Versa 630 XRM and reconstructed using ZEISS DeepRecon. An inverted LUT has been applied.
    Sample courtesy of Dr Kevin Boergens, University of Illinois at Chicago, USA.

High-powered resolution performance with RaaD 2.0

ZEISS introduces higher energy capabilities and the new 40X Prime (40X-P) objective with ZEISS Xradia 630 Versa. Known for their ability to achieve Resolution at a Distance (RaaD), ZEISS Xradia Versa systems allow a wide array of sample types and sizes over a long range of length scales at high resolution. With 40X-P, the system achieves unparalleled resolution performance of 450-500 nm across the full range of energy, from 30 kV to 160 kV, defining RaaD 2.0 and unlocking entirely new application capabilities for researchers.

The user experience evolves for expanded accessibility

Novel X-ray imaging can be complex, so ZEISS XRM researchers studied user habits, dove into their challenges, and employed human-centered design principles for ZEISS Xradia 630 Versa. Now even the newest user can be immediately productive. The NavX software guides users through automated workflows with intelligent system insights and delivers experimental results more easily and efficiently while also allowing experienced users to explore the full versatility of ZEISS Xradia 630 Versa.

Additionally, the NavX File Transfer Utility (FTU) takes the data that is being produced by the microscope and automatically transfers it to other locations so that users have access where they need it, when they need it.

Game-changing AI

With the simultaneous launch of ZEISS Advanced Reconstruction Toolbox (ART) 3.0, ZEISS offers the AI Supercharger package with the all-new ZEISS DeepScout as well as ZEISS DeepRecon Pro modules for all ZEISS Xradia Versa systems. ZEISS DeepScout uses high-resolution 3D microscopy datasets as training data for lower resolution, larger field of view datasets and upscales the larger volume data using a trained model, representing effective throughput boosts of 100 times what can be achieved by a very high spatial resolution at an equivalent volume. ZEISS DeepRecon Pro provides high throughput and image quality benefits across a diverse set of sample types.
This capability is available for the ZEISS Xradia 630 Versa platform, which provides maximum integration and power to seamlessly deliver resolution across large fields of view (FOV) with high throughput.

ZEISS DeepScout for Reliability Study of A12 Smartphone Package 0-3sec: Large field of view (LFOV) scan. FOV - 20x30 mm @10 µm/voxel 4-6 sec: High-resolution scan at 2.1 µm/voxel for network model training 14-16 sec: High-resolution data can be acquired anywhere 19-22 sec: ZEISS DeepScout recovers resolution for the entire volume. It would take 125 high-resolution scans to acquire the same data. 30-33 sec: A ZEISS DeepScout volume with restored resolution.

Daniel Sims, head of ZEISS X-ray Microscopy, says, “With our new flagship instrument, we are offering really innovative technologies that are integrated in a very powerful way. Our goal in developing this new XRM was to not just extend the imaging capability but to also ensure that all our users could easily access the full potential of the system, and that all customers will benefit from the increased productivity in their applications. We’re confident that ZEISS Xradia 630 Versa has achieved this result – the imaging capability has been extended significantly and it is quicker and easier to use. Both beginners and experts will be able to get faster results with greater insights making them more successful in their experiments and their facilities.”

Press Contact Vybhav Sinha ZEISS Research Microscopy Solutions

About ZEISS

ZEISS is an internationally leading technology enterprise operating in the fields of optics and optoelectronics. In the previous fiscal year, the ZEISS Group generated annual revenue totaling 8.8 billion euros in its four segments Semiconductor Manufacturing Technology, Industrial Quality & Research, Medical Technology and Consumer Markets (status: 30 September 2022).

For its customers, ZEISS develops, produces and distributes highly innovative solutions for industrial metrology and quality assurance, microscopy solutions for the life sciences and materials research, and medical technology solutions for diagnostics and treatment in ophthalmology and microsurgery. The name ZEISS is also synonymous with the world's leading lithography optics, which are used by the chip industry to manufacture semiconductor components. There is global demand for trendsetting ZEISS brand products such as eyeglass lenses, camera lenses and binoculars.

With a portfolio aligned with future growth areas like digitalization, healthcare and Smart Production and a strong brand, ZEISS is shaping the future of technology and constantly advancing the world of optics and related fields with its solutions. The company's significant, sustainable investments in research and development lay the foundation for the success and continued expansion of ZEISS' technology and market leadership. ZEISS invests 13 percent of its revenue in research and development – this high level of expenditure has a long tradition at ZEISS and is also an investment in the future.

With over 38,000 employees, ZEISS is active globally in almost 50 countries with around 30 production sites, 60 sales and service companies and 27 research and development facilities (status: 30 September 2022). Founded in 1846 in Jena, the company is headquartered in Oberkochen, Germany. The Carl Zeiss Foundation, one of the largest foundations in Germany committed to the promotion of science, is the sole owner of the holding company, Carl Zeiss AG.

Further information at www.zeiss.com

ZEISS Research Microscopy Solutions

ZEISS Research Microscopy Solutions is the world's only one-stop manufacturer of light, electron, X-ray and ion microscope systems and offers solutions for correlative microscopy. The portfolio comprises of products and services for life sciences, materials and industrial research, as well as education and clinical practice. The unit is headquartered in Jena. Additional production and development sites are located in Oberkochen and Munich, as well as in Cambourne (UK) and Dublin (USA). ZEISS Research Microscopy Solutions is part of the Industrial Quality & Research segment.


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