ZEISS Solutions for Biopharma & Biotech Scientists

Maximize Your Microscopy ROI with the Right Solutions Provider

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Microscopy solutions that scale with your business plan

ZEISS microscopy professionals can help you find the right solutions and provide sound advice to help minimize your risk and reduce your time to market.

Securing your imaging solutions

From leasing to venture capital options, ZEISS has flexible solutions for acquiring the imaging technology you need to succeed.

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The right imaging solution for you

ZEISS has the most powerful portfolio of technologies. Here are a few examples:

Live cells in a 384 microwell plate imaged automatically with ZEISS Celldiscoverer 7. Images are crisp enough for auto segmentation and cell counting analyses. Courtesy of P. Denner, German Center of Neurodegenerative Diseases (DZNE), Germany

High throughput imaging requires automated solutions. With ZEISS, digitize up to 100 large area brain or tissue section slides at high speed and in high resolution. Or automate your live cell imaging of samples in dishes or multiwell plates with systems designed to keep your samples alive while capturing data over hours to days with minimal supervision.

Non small cell lung cancer (NSCLC) tissue labeled with Ultivue Ultimapper kit to study the tumor microenvironement with tissueomics. Image acquired with ZEISS Axioscan 7 digital slide scanner.

Multiplex microscopy and spatial phenotyping for tissueomics are unveiling tumor and tissue microenvironments. From confocal microscopes to digital slide scanners to widefield research microscope platforms with powerful software analyses, ZEISS offers solutions with the combination of large area imaging, high spatial resolution and accurate fluorophore emission separation for your most challenging tissueomics experiments.

Human breast cancer organoid grown in a multiwell plate with Matrigel. Imaged with confocal microscopy. Courtesy of S. Gawrzak and M. Jechlinger, European Molecular Biology Laboratory, Germany

Organoids and 3D cell cultures present challenges for high resolution imaging from their dense gel media to their distance from the cover glass. From confocal to light sheet microscopes, ZEISS offers extremely sensitive imaging systems that provide amazing high resolution, 3D data of these delicate structures.

Thy1 EGFP mouse brain cleared with a modified version of iDISCO. Imaged with light sheet microscopy. Courtesy of S. Gandhi, University of California Irvine and Translucence Biosystems, USA

Optical tissue clearing techniques have enabled light microscopes to image entire brains and other organs with subcellular resolution. Regardless of which clearing technique you use, ZEISS imaging solutions balance the challenge of large sample sizes with high resolution and high acquisition speed, allowing you to image your entire sample with clarity in a shorter amount of time.

Rat kidney histology slide, documented with brightfield microscopy

Lab documentation of routine work must be fast, easy and accurate. With ZEISS Smart Microscopy, press a single button on your microscope stand and acquire crisp images in true color, just as you see them through the eyepieces. The system automatically adjusts all parameters and adds the correct scaling information to your saved image.

Increase your speed to data

ZEISS knows how critical it is that you acquire accurate data in the shortest possible time. Whether you are working with whole slide imaging using digital slide scanners to 3D imaging of organoids or tissues, we can help you improve your ROI:

 
Improve your workflow
From custom tailored hardware to personalized software, we can work with you to ensure your technology is acquiring the data you need in the most efficient way possible.

Data analysis powered by deep learning
ZEISS software solutions using artificial intelligence enable automated segmentation and image analyses. Batch process hundreds of images automatically and decrease your time from experimental design to data. ZEISS AI solutions are designed to be easy to implement so that even novice users can reduce their time from data to results.
Automated object classification for cell counting analyses.

Introducing ZEISS Axioscan 7

Multiplex Imaging Solution - Transforming Slides to Results

Experience the evolution in automated whole slide imaging for brightfield, fluorescence, and polarization applications. Achieve faster brightfield scanning with flash mode and the Axiocam 705 color camera.

The use of multichannel immunofluorescence techniques expands your opportunity for research and discovery, increasing output from precious sample material. Our dynamic slide scanner offers full spectral flexibility pairing the Colibri 7 with discrete single bandpass filters, multi bandpass filters, and fast filter wheels. Self-monitoring in the Colibri 7 ensures precise power output of its ultra-fast switching LEDs for reproducible fluorescence acquisition.

Imaging multiplexed tissue is now faster and gentler than ever with the introduction of a new patented contrast technique. The Transfer of Intensity Equation, or TIE contrast, offers damage-free, high speed focusing of fluorescence material. Stained, label-free, and low contrast samples are all made visible with unsurpassed optical quality. Capture the whole picture, hundreds of slides at a time, without application restrictions.


Key Learnings:

  • The main drivers that push researchers to move to an automated platform
  • How Axioscan 7 makes routine imaging more efficient
  • Example applications of multiplex imaging in the mouse brain

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