ZEISS Elyra 7 with Lattice SIM²

Your Live Imaging System with Unprecedented Resolution

The super-resolution microscope Elyra 7 takes you far beyond the diffraction limit of conventional microscopy: With Lattice SIM² you can now double the conventional SIM resolution and discriminate the finest sub-organelle structures, even those no more than 60 nm apart. You don‘t need to sacrifice resolution when imaging at high speed using only the minimal exposure needed for life observation. Elyra 7 enables you to combine super-resolution and high-dynamic imaging – without the need for special sample preparation or expert knowledge of complex microscopy techniques.

Reveal the vibrant sub-organelle network of life:

  • Resolve structures down to 60 nm.
  • Observe live cell dynamics at up to 255 fps.
  • Accelerate image acquisition in all three dimensions.
  • Get the sharpest sectioning in wide-field microscopy.
  • Utilize a wealth of imaging techniques on one platform.
With SIM² on the microscope system ZEISS Elyra 7, life science researchers can now double the conventional SIM resolution.

Did you miss the “Join us at 60 nm” launch event?

Watch the event recording here.

Learn how to reveal sub-organelle structures down to 60 nm, capture highly dynamic processes at exceptional resolution, get outstanding out-of-focus light suppression, and make super-resolution acquisition faster than ever before.

Lattice SIM²

Double Your SIM Resolution

SIM² is the novel, groundbreaking image reconstruction algorithm that increases the resolution and sectioning quality of structured illumination microscopy data. SIM² is compatible with all SIM imaging modes of your Elyra 7 and fully integrated in the ZEN software.

Images of Cos-7 cell stained with anti-alpha-Tubulin Alexa fluor 488 were processed with the conventional SIM algorithms based on generalized Wiener filter and with the novel SIM² reconstruction. The images show an improvement of resolution for SIM² compared to SIM. Objective: Plan-Apochromat 63× / 1.4 Oil

SIM² Apotome and Leap Mode

Gentle Sectioning Made Three Times Faster

SIM² Apotome is superior to conventional confocal microscopy in terms of lateral and axial resolution as well as volume acquisition speed while it is also very gentle to your sample. Elyra 7 Leap mode accelerates the volume imaging speed three times and at the same time decreases the light dosage on your sample for both Lattice SIM² and SIM² Apotome.

U2OS cell expressing calreticulin-tdTomato to visualize the endoplasmic reticulum. The time series shows a maximum intensity projection of the volume data set.

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