Experience Spatial Biology in 3D with the ZEISS LSM 980

ZEISS On Your Campus (ZOYC) Event

Join us for an introductory webinar and schedule an in-person demo

Hosted by Clarence Yapp, Director of Microscopy and Image Analysis, at the Laboratory of Systems Pharmacology, Harvard Medical School

Our ZEISS On Your Campus (ZOYC) roadshow is touring the country with our ZEISS LSM 980. This special workshop will focus on applying our 3D spectral multiplexing confocal technology to a wide range of spatial omics applications.

WEBINAR

ZEISS 3D solutions for Spatial Omics

June 21, 2022 | 2 pm EDT

Join us for our special workshop focused on applying our 3D spectral multiplexing confocal technology to a wide range of spatial omics applications. The workshop will consist of a webinar covering the technology and applications and a discussion on a number of our ZEISS analysis software solutions relevant to this application space. 

In this workshop, you will learn:

  • How to apply our 3D spectral multiplexing confocal technology to a wide range of spatial omics applications
  • How the new NIR technology on the LSM 980 allows you to expand your spectral palette
  • New tools such as LSM Plus to further increase resolution and sensitivity and acquire the signature of even up to 10 or more markers in a single scan
  • A number of our ZEISS analysis software solutions relevant to this application space
     

Abstract

In the past 5 years, the life sciences community has witnessed the progression of the genomics and proteomics world into the spatial domain. This was in large part due to a strong desire to not only know which genes were being turned on and which proteins were being expressed, but also precisely where in a much larger context. This concept, often referred to as actionable biology, is leading to a much deeper understanding of diseases and genetic disorders and is transforming the developments of treatments, cures, and drug discoveries. Certainly, the spatial concept easily lends itself to microscopy methods, and we have seen the release of many powerful instruments on the market dedicated to spatial omics applications. Initially, this work was almost exclusively being done on very thin tissue sections or monolayers of cells, and therefore, 2D imaging using widefield microscopy was sufficient. However, biology is inherently 3D, and the desire to resolve information in all three dimensions, even in relatively thin sections, is increasing. Furthermore, we see researchers pushing these methods into even thicker tissue samples, and therefore, this obviates the need for an optical sectioning microscopy method to accomplish the imaging goals. The ZEISS LSM 980 with NIR detection is well suited to address this need, and furthermore provides the most spectral flexibility to meet the demands of the growing number of biomarkers needed to be interrogated in a single imaging cycle, as well as smFISH probes pushing out into the NIR wavelength range. With new tools such as LSM Plus to further increase resolution and sensitivity, we can now acquire the signature of even up to 10 or more markers in a single scan; therefore, increasing throughput and productivity.

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In-person Demos

In addition to the webinar, 2-hour in-person demos are available at Harvard Medical School from June 21-24, 2022. Due to COVID-19 safety precautions, we can accommodate small groups (up to 3 people) per demo session. Additional colleagues will need to sign up for a separate session. Space is limited.

Register

This webinar is presented by Samantha Fore, Ph.D.

Product Marketing Manager – Life Sciences Laser Scanning Microscopy (LSM)

Samantha is the Life Sciences LSM Product Marketing Manager for ZEISS RMS in North America. She has been in that role since 2020. Prior to transitioning to the Marketing group, she spent 7 years in the Sales group as a Product and Application Sales Specialist supporting the advanced 3D imaging portfolio for ZEISS, first in New York, and then out West in the San Francisco Bay Area. It is in that role, that she developed a clear fondness for the LSM platform from ZEISS and became passionate about marrying its unique capabilities with the latest emerging and powerful applications in the life sciences, such as 3D spatial omics. She continues her dedication and enthusiasm towards this goal in her current role and can still be regularly found collaborating with colleagues and customers to further develop these workflow solutions integrating the LSM platform.  

Samantha's Bio collapse

This webinar is presented by Kevin O'Keefe, Ph.D.

Senior Software Sales Biotech Pharma

Prior to joining ZEISS Kevin O’Keefe completed his Ph.D. at the University at Albany, SUNY, where he gained extensive experience in widefield, confocal microscopy and image analysis with a focus on tissue multiplexing following injury in the mouse submandibular salivary gland. After graduating Kevin started his career at ZEISS as a Product Application Sales Specialist and covered NY, NJ and PA working with ZEISS hardware including advanced 3D imaging systems. Recently, Kevin has joined the software sales team as the Senior Software Sales Representative with a concentration in biotech and pharma. He focuses on using the ZEISS toolkit for image analysis including ZEN, APEER and Arivis to help translate images into actionable data.

Kevin's Bio collapse

This webinar is presented by Tanay Desai, Ph.D.

Product Application Sales Specialist

Tanay joined ZEISS as an Imaging Specialist in 2016 and in his role covers Boston/Cambridge and the New England area. Prior to his time with ZEISS, he was a post-doctoral fellow at Emory University, where he worked on imaging, assay-design and biophysical approaches to the study of viral entry and cellular entry mechanisms. He received his doctorate from the University of Maryland in Biophysics and Biochemistry, with a focus on protein folding mechanisms and spectroscopy.

Tanay's Bio collapse