Use the optical trap and microbeam for isolating cells, groups of cells and biomolecules with the PALM CombiSystem.
PALM CombiSystem
Two Non-Contact Laser Technologies in One System

PALM CombiSystem

Laser microdissection and optical tweezers in a single system

PALM CombiSystem combines two non-contact laser technologies in one system. It allows you to precisely microdissect and capture samples of interest and to optically trap small objects, such as living cells.

Micromanipulations Made Accurate and Simple

PALM CombiSystem combines laser microdissection with optical trapping. For laser microdissection mark an element on your screen and then start the laser to separate it from unwanted tissue. A targeted laser pulse will 'catapult' your element upwards and contact-free into a collection vessel for further analysis.

The optical trap of PALM CombiSystem manipulates particles with the highest precision at the cellular and sub-cellular level. This allows you to trap, move and position microscopic objects — such as red blood cells and bacteria — intuitively with the force of light.

Highlights

Extend Your System to a Complete Research Platform

PALM CombiSystem offers you exceptional control over laser micromanipulation. It allows you to:

  • Microdissect samples from fixed material to living cells for DNA, RNA and protein isolation
  • Applicable to cryosections, FFPE (formalin fixed and paraffin embedded) tissue sections, cell smears, cytospins, chromosome preparations and live cells
  • Trap, sort and position with the highest precision
  • Manipulate and move particles and living cells in liquids
  • Connect modular equipment, such as AxioCam high-resolution digital cameras for fluorescence and bright field that brings additional clarity to your work
  • Enjoy an intuitive user interface and functions that are easily incorporated into your workflow
  • Benefit from the expertise and technical support of the ZEISS specialists


PALM CombiSystem by ZEISS Microscopy is a platform that can be integrated with future-oriented technologies — ensuring many years of flexible service in your lab.

Integration

PALM CombiSystem is Integrated Into the System World of ZEISS

PALM CombiSystem is supplied together with the Axio Observer inverse research microscope. That means you not only benefit from an optical trap and microdissection capabilities, but you also enjoy exceptional, proven ZEISS imaging quality.

In addition, your PALM CombiSystem is compatible with many other ZEISS components, allowing you to extend your system and create the versatile research platform you demand with a maximum return on your investment.

Technology

Contact-free High Precision Micro-manipulation

PALM CombiSystem uses a focused laser beam to cut out and isolate your selected specimen without contact. The patented laser catapult isolates your target area fast and uncontaminated.

In addition, PALM CombiSystem provides optical tweezers. These are the ideal solution if you demand a high-precision tool for the separation and manipulation of particles at the cellular and sub-cellular level.


Applications

Downloads

The PALM Family - A New Dimension in Sample Purity

Integrated Laser Microdissection and Microscope Systems for Live Cells and Fixed Material

Pages: 23
Filesize: 4,842 kB

Application Note: Laser Microdissection: A Key Technology for Microproteomics

Isolate a single cell population Isolate 30.000 cells in one step within seconds Seamless integrate LCM into your workflow

Pages: 7
Filesize: 2,198 kB

Currently hundreds of publications have been published using our Microdissection-Systems, and the list continues to grow. Bookmark this section to stay informed about the latest advances in laser micromanipulation techniques for medical and biological research.

 

Download Publications
MicroBeam
CombiSystem & MicroTweezers


Protocols

Download Protocols here
ZEISS Labs - the unique microdissection service

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