ZEISS Axioscope 5

Your Smart Microscope for Biomedical Routine and Research

In the past, documenting samples with multiple fluorescent labels in your routine lab could be time consuming. To get best image quality, you needed to manually switch filters, adjust illumination intensities and exposure times and to snap each single channel image. For four different channels, this could sum up to 15 steps and clicks. With Smart Microscopy, this is a thing of the past. Axioscope 5 with Axiocam 202 mono and Colibri 3 LED illumination take this workload from you. You don't even need to move your hands from the microscope stand anymore. All you have to do is focus and press Snap – and you're done! You can now concentrate on the essence of your job and let Axioscope 5 work for you. You'll work more efficiently, save time and produce high contrast images with best image quality.


Four Multichannel Fluorescence Channels with Just One Click

Acquiring fluorescent images has never been so easy. Combine Axioscope 5 with the LED light source Colibri 3 and the sensitive, standalone microscope camera Axiocam 202 mono to have the perfect setup for easy multichannel fluorescence documentation.
Switch effortlessly between the channels for UV, blue, green and red excitation. Just select the relevant channels and press Snap. The system then takes over and automatically adjusts the exposure time, acquires the image, switches the channel and starts again. That's it: you get your overlayed multichannel fluorescence image including scale bar – even without a PC.

Smart Microscopy Makes Your Digital Documentation Faster

Axioscope 5 makes documenting your specimens very efficient. The color impression shows up in the camera image exactly the same as it appears through the eyepieces. This smart microscope makes automatic adjustments for brightness and white balance to keep digital documentation easy. All you have to do is focus on your sample, press the ergonomic Snap button on the microscope, and that's it.

Benefit from Homogenous Illumination

Axioscope 5 uses its LED to provide powerful illumination with high color fidelity. You will clearly see the subtle differences in your sample. And experience all the advantages of LED illumination such as

  • stable color temperature,
  • low energy consumption
  • long lifetime

Axioscope 5 comes with a light intensity manager that produces uniform brightness at all magnifications. Adjusting lamp brightness when you change magnification is a thing of the past. That saves you time and reduces eye fatigue, too.

This is Smart Microscopy

Digital Documentation Made Easy

Used in combination with Axiocam 202 mono or Axiocam 208 color, you have the full advantage of a smart standalone microscope system. Camera settings such as white balance, contrast and exposure time are done automatically. Without needing additional imaging software or even a computer, you can:

  • Snap images and record videos directly from your stand
  • Use the mouse to control your camera via on-screen display (OSD)
  • Save settings
  • Store images with all metadata of the microscope and camera as well as scaling information
  • Predefine the name or rename your image
Axioscope 5 snap-hands-on


With Axioscope 5 and Smart Microscopy you are prepared for today and the future. Choose the configuration, which suits best to your lab workflow:

Stand-alone for Basic Routine Imaging
  • Stand-alone for basic routine imaging
    Axioscope 5 in combination with Axiocam 202 mono or Axiocam 208 color operates independently of a computer system.
ZEISS Labscope for Advanced Routine Imaging
  • ZEISS Labscope for advanced routine imaging
    Operating Axioscope 5 and Axiocam 202 mono or Axiocam 208 color with the imaging app Labscope is the ideal choice for connected microscopes and standard multichannel fluorescence imaging.
ZEISS ZEN for Research Applications
  • ZEISS ZEN for research applications
    With the imaging software ZEN you can perform advanced imaging tasks with your Axioscope 5.

ZEISS Colibri 3 LED Illumination

Complement your Axioscope 5 with the optional fluorescence LED illumination Colibri 3, and acquire brilliant fluorescence images with ease. Colibri 3 delivers the right wavelength and intensity to excite fluorescent dyes and proteins in a gentle way.

  • Save time and money thanks to the long LED lifetime, the adjustment-free operation, and the avoidance of warm-up or cool-down times.
  • Choose up to four configurable wavelengths to fit your needs. Upgrade anytime you need to.
  • Individually control and switch between channels for UV, blue, green and red excitation – or use selected wavelengths simultaneously.
  • With direct visual status feedback, you are always sure which FL-LED is in use.
  • The integrated design saves space and makes for easy and ergonomic operation.

ZEISS Axioscope 5 at Work

With its wide range of contrasting techniques, Axioscope 5 is perfectly suited for routine as well as for research applications in:

  • Biology research
  • Human & veterinary medicine
  • Microbiology
  • Plant Sciences & Botany
  • Forensics
Histological specimen (human)
Histological specimen (human)
Chromosome specimen (human)
Chromosome specimen (human)
Renal tissue (human)
Renal tissue (human)
Mink Uterus Endometrium Epithelial Cells
Mink Uterus Endometrium Epithelial Cells
Indian muntiac, fibroblasts
Indian muntiac, fibroblasts
Mouse kidney in fluorescence
Mouse kidney in fluorescence
Novicula Lyra
Novicula Lyra
Trout cartilage
Trout cartilage


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Your Smart Microscope for Biomedical Routine and Research

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