Spatial Biology Imaging

The Axioscan 7 spatial biology can separate 8 fluorescence channels, currently supported by Kromnigon SpectraClick reagents. A typical panel could consist of 7 target markers plus DAPI. Supported fluorophores include DAPI, CFP, GFP, DsRed, Cy3, Cy5, Cy7 and fluorophores with similar spectral properties. Single round staining and single shot imaging can be done for 8-channels. For going to higher marker numbers (e.g. 14, 28, etc.) cyclic staining and imaging can be performed.

The physical slide capacity of the system is 100 slides (25 trays, 4 slides each). The system can image over 100 slides per day thanks to the high level of automation and high scan speed. 10 mm2 tissue area can be scanned in 3 to ~10 minutes pure scan time for 5- or 8-Plex respectively.

Yes. A single run can include up to 100 slides, each potentially containing multiple tissue sections or cores. Pre-configured scan profiles for mIF and chromogenic assay stained tissue can be selected per sample, allowing users to load and run diverse experiments in one batch, in a single automated workflow.

No prior microscopy experience is required. The software and scanner are designed for ease of use, with an intuitive interface and automated workflows that enable any operator to run the system efficiently, with minimal or no training.

The Axioscan 7 connects to the LIMS by scanning QR codes or barcodes printed on the slide labels. The scanner reads the slides unique ID from the code on the sample, retrieves the required additional information from the LIMS, which will be used to automatically populate the SlideStream interface with the relevant details, streamlining the workflow and reducing the need to manually re-enter pre-existing data.

For optimal performance, we recommend using the latest version of Google Chrome, a stable internet connection with at least 10 Mbps bandwidth, and a computer running a current, up-to-date operating system. These requirements ensure smooth and responsive operation of the platform.

Yes, local deployment is possible. For customers handling large image volumes or requiring local data storage, Mindpeak offers hybrid deployment options. In this setup, data is stored on the customer’s server while processing is performed on Mindpeak’s secure cloud infrastructure, helping reduce storage costs while maintaining greater control over sensitive data.

Storage limitations are defined by the IT infrastructure of customers as defined in their purchased packages. Additional storage capacities can always be acquired ad hoc in alignment with customer needs and budget requirements.

We partner exclusively with ISO 27001-certified cloud providers, such as AWS and Hetzner, to ensure enterprise-grade data protection. All data is encrypted both at rest and in transit, and regular security audits are performed to safeguard your sensitive research. These measures ensure your data remains secure, private, and fully under your control.

• https://d1.awsstatic.com/certifications/iso_27001_global_certification.pdf
• https://www.hetzner.com/assets/downloads/FOX-Zertifikat.pdf