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NSCLC tissue stained with UltiMapper I/O PD-L1 kit.

NSCLC tissue stained with UltiMapper I/O PD-L1 kit. Picture detail.

Mouse spleen fresh frozen sections, 8-plex staining of CD11c, CD4, F4/80, CD8, CD11b, B220, CD169, DAPI using Kromnigon StreptaClick^® technology. DAPI is not shown on this image.

Mouse spleen fresh frozen sections. Picture detail.

Human tonsil FFPE tissue section stained with Ki67, GranzymeB, CD3, CK/SOX10, DAPI.

A composite image of Non-Small Cell Lung Cancer tissue, stained with Ki67, GranzymeB, CD3, CK/SOX10, DAPI.

^{Sample is courtesy of Concept Life Sciences, CRO in UK.}

A mouse liver FFPE tissue section stained with 6 biomarker targets and DAPI.

A mouse liver FFPE tissue section. Picture detail.

Colon cancer spheroid co-cultured with fibroblasts. FFPE sections stained for Filaggrin, Ki67, Collagen-1, E-cadherin, DAPI. The spheroids were grown, fixed, paraffin embedded, cut and stained at Bioneer A/S (Hørsholm, Denmark)

The cancer spheroid shown here contains HT29 colon cancer cells, fibroblasts and bead-activated T cells, and shows a partly disintegrated spheroid structure, where the damage is caused by cytotoxic T-cells (CD8 positive, yellow). HT29 cells are stained with the panCK antibody (red). A subset of T cells is PD-1 positive (purple). The fibroblasts remain unstained (dense DAPI-positive structure) except for some Ki67 staining. A subset of CD8⁺ cells is co-expressing Ki67. The spheroids were grown, fixed, paraffin embedded and cut at Bioneer A/S (Hørsholm, Denmark).

Movat staining

AZAN staining

Goldner staining

Weigert-Van Gieson (WvG) staining

Movat staining

Weigert-Van Gieson (WvG) staining

Goldner staining

Hematoxylin and Eosin (H&E) staining

Circular Polarization

Cross Polarized Light (XPL)

Plane Polarized Light (PPL)

Automated machine learning-based mineral classification uses a single ZEN Intellesis model, applied here on two sandstone samples.

Both modal mineralogy and pore / grain sizes can be measured and automatically reported.

Full thin-section polarization images. This kyanite-bearing schist has been imaged as part of a digital thin section collection. The upper image shows a single PPL orientation while the lower view shows the capture of the thin section in multiple XPL orientations. This lets a simulated stage rotation observe and analyze extinction angles with the full XPL variation over 90°.

Close up of a single biotite grain within a granite sample. Sample has been imaged in multiple PPL orientations in order to observe the full range of pleochroism as the sample is rotated through 180° relative to the polarizer.

Use ZEN Connect to build intuitive correlative projects that start with the data-rich light microscopy environment from ZEISS Axioscan 7 geology. Here additional phase and geochemical information from ZEISS Mineralogic becomes the next step in a petrological investigation. The sample shown here is a granulite facies metagabbro from near Scourie more, Northwest Scotland.