Skip to main content
Research Microscopy Solutions
back
Research Microscopy Solutions
recommended searches
popular searches
ZEISS Axio Imager 2​
Product

ZEISS Axio Imager 2

Upright microscope platform for productive high-resolution imaging

Explore cellular structures and processes of your biological specimens at unprecedented levels of detail. Whether you are conducting cellular biology studies, histological examinations, or cancer research, you can be ensured with the versatility and performance needed to enhance your research outcomes.

  • Highest contrast and resolution across a large field of view
  • Human-centered design for comfortable observation
  • Modular setups designed for efficient imaging
U2OS cells stained with Phalloidin

U2OS cells stained with Phalloidin

U2OS cells stained with Phalloidin

High-performance optics with 25 mm field of view allow you to simply see more in every image. Detect more cells per shot or scan large areas faster for highest productivity. U2OS cells stained with Phalloidin (green, actin) and Hoechst (blue, DNA), acquired using a Plan-Apochromat 20× / 0.8 objective.

Optical excellence

Highest contrast and resolution across a large field of view

A stable imaging system with high-quality optics is essential to achieve the clarity and resolution required to understand biological processes. With ZEISS Axio Imager 2, you can rest assured that you have the best optics to support your research. The z-drive features a 10 nm step size, ensuring precise focusing of your sample and maintaining its position. The stable imaging cell was designed for a vibration-free proximity between the filter cubes, camera, and objective, ensuring highest image quality and reproducibility. The 25 mm field of view allows you to image larger areas of your sample faster.

Caption: High-performance optics with 25 mm field of view allow you to simply see more in every image. Detect more cells per shot or scan large areas faster for highest productivity. U2OS cells stained with Phalloidin (green, actin) and Hoechst (blue, DNA), acquired using a Plan-Apochromat 20× / 0.8 objective.

Ergonomic phototubes: Adjust ZEISS Axio Imager 2 to your personal preferences and observe your specimen without fatigue over extended periods of time.

Ergonomic phototubes

Ergonomic phototubes: Adjust ZEISS Axio Imager 2 to your personal preferences and observe your specimen without fatigue over extended periods of time.
Ergonomic phototubes: Adjust ZEISS Axio Imager 2 to your personal preferences and observe your specimen without fatigue over extended periods of time.
Ergonomic phototubes: Adjust ZEISS Axio Imager 2 to your personal preferences and observe your specimen without fatigue over extended periods of time.

Ergonomic excellence

Human-centered design for comfortable observation

Tailor the setup to your personal preferences with ergonomic phototubes for comfortable viewing. Customize the microscope for quick access to frequently used functions or user-specific settings. ZEISS Axio Imager 2 is also designed to work without a connected PC. With a smart Axiocam camera, you can display images on an external monitor or TV and save your images directly to a memory stick.

ZEISS Axio Imager 2 with LSM 990 Airyscan and incubator

ZEISS Axio Imager 2 with LSM 990 Airyscan and incubator

ZEISS Axio Imager 2 with LSM 990 Airyscan and incubator

Modular excellence

Custom setups designed for efficient imaging

ZEISS Axio Imager 2 can be adapted to your application requirements with a high degree of freedom. It is compatible with fast and sensitive cameras of the ZEISS Axiocam portfolio as well as with cameras from other manufacturers. Choose from bright and efficient multi-LED light sources from the ZEISS Viluma family and pair them with up to 10 filter sets for maximum spectral flexibility. Expand your configuration with Apotome 3 or an LSM confocal—supplemented by an XL incubator for imaging at elevated temperatures if required.

Turn clarity into discovery

ZEISS Axio Imager 2 at work
  • High-throughput TMA analysis
  • Fixed U2OS cells with stained lysosomes
  • Fixed human tonsil sample stained for DNA
  • Hematoxylin and eosin-stained section of an embryonic fisheye
  • Human brain tissue stained with anti-GFAP antibody
  • Tumor micro-environments in tonsil tissue
  • Tiled overview image of human tonsil sample stained for DNA
  • High-throughput TMA analysis: 13 tissue stamps were screened using a set of seven markers for tumor analysis to gain insights into tumor-immune interactions and find potential therapeutic targets.

    High-throughput TMA analysis: 13 tissue stamps were screened using a set of seven markers for tumor analysis to gain insights into tumor-immune interactions and find potential therapeutic targets.

  • Fixed U2OS cells with stained lysosomes (yellow), DNA (blue) and actin (magenta)

    Fixed U2OS cells with stained lysosomes (yellow), DNA (blue) and actin (magenta)
  • Fixed human tonsil sample stained for DNA (blue), panCK (green), CD3 (orange), PD-L1 (red), CD68 (purple)

    Fixed human tonsil sample stained for DNA (blue), panCK (green), CD3 (orange), PD-L1 (red), CD68 (purple)
  • Hematoxylin and eosin-stained section of an embryonic fisheye

    Hematoxylin and eosin-stained section of an embryonic fisheye (Nothobranchius furzeri). Sample courtesy of Annekatrin Richter, Leibniz Institute on Aging, Fritz Lipmann Institute e.V. (FLI), Jena, Germany.
  • Human brain tissue stained with anti-GFAP antibody

    Human brain tissue stained with anti-GFAP antibody (DAB, brown) to identify glia cells and hematoxylin counterstain
  • Tumor micro-environments in tonsil tissue

    Spatial biology unveiled: a 7-color staining approach to tumor micro-environments in tonsil tissue. Spectral unmixing was employed to effectively separate the seven dyes, ensuring accurate identification of each marker.
  • Tiled overview image of human tonsil sample stained for DNA

    Tiled overview image of human tonsil sample stained for DNA (blue), panCK (green), CD3 (orange), PD-L1 (red), CD68 (purple). Detailed view acquired with ZEISS Apotome 3.

The ZEISS Axio Imager 2 Product Family

The perfect stand tailored to your needs

  • ZEISS Axio Imager.A2

    This manual stand is ideal for observation tasks. The ergonomic stand design features research-grade optics, allowing you to see even the finest details and the most accurate colors.

  • ZEISS Axio Imager.D2

    This stand is suited for swift transitioning between observation and imaging. It can be equipped with a motorized reflector turret for automated multi-channel fluorescence imaging.

  • ZEISS Axio Imager.M2

    This highly motorized stand enables the automatic execution of complex acquisition tasks. It performs automated scanning of large areas or creates 3D representations of your samples.

  • ZEISS Axio Imager.Z2

    This stand incorporates the full capabilities of the Axio Imager 2 platform. For laser-based or cryogenic microscopy, its highest level of motorization enables the most complex workflows.

Related applications

Cell Imaging with Fluorescence Microscopy

With different technologies available that balance sensitivity, resolution and fluorophore requirements, explore your options from widefield to deconvolution, confocal to super-resolution.

Imaging Large Brain and Tissue Sections – Whole Slide Imaging

Learn about solutions that make your high-throughput slide imaging efficient and analysis easy and reproducible.

Live Cell Imaging

In addition to meeting your needs for high-resolution fluorescence imaging, learn about technologies that also provide superbly gentle imaging at faster speeds.

Downloads

  • Preview image of ZEISS Axio Imager 2

    ZEISS Axio Imager 2

    Upright Microscope Platform for Productive High-Resolution Imaging

    7 MB
    Download
  • Preview image of ZEISS Microscope Bundle for Optical Sectioning

    ZEISS Microscope Bundle for Optical Sectioning

    Creating crisp sections of thick samples with ease

    328 KB
    Download
  • Preview image of ZEISS Microscope Bundle for Screening Applications

    ZEISS Microscope Bundle for Screening Applications

    Fast acquisition and evaluation of large areas

    425 KB
    Download

Visit the ZEISS Download Center for available translations and further manuals.

Contact ZEISS Microscopy

Upgrade/Retrofit

Training

Software Finder

Software Download

Contact

Form is loading...

/ 4
Next Step:
  • Step 1
  • Step 2
  • Step 3
Contact us
Required Information
Optional Information

If you want to have more information on data processing at ZEISS please refer to our data privacy notice.

Service & Support