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Life Science

Cell Biology

Unravel mysteries at the cellular level

Explore cell structures in unprecedented detail with ZEISS advanced imaging and analysis solutions.

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Unlock cellular secrets with advanced microscopy

Visualize, analyze, and quantify cellular structures and dynamic processes across multiple scales—from whole cells to sub-cellular components—using advanced imaging and analysis technologies. Their portfolio supports applications such as high-resolution live-cell imaging, investigation of organelle dynamics, 3D cell cultures, intracellular signaling pathways, and developmental or functional studies, while integrating AI-driven image analysis and correlative workflows to turn complex imaging data into measurable insights. Overall, these tools are designed to provide the speed, resolution, and flexibility needed to study cellular behavior in real time and drive deeper understanding of biological mechanisms.

Cell Biology Use Cases

The precision, flexibility, and support needed to drive scientific discovery.
Cell Biologyy Use Cases
Instant Volumetric Imaging
Gentle Illumination
Spatiotemporal Resolution
Lightsheet Imaging
Spectral Multiplexing
Live Imaging

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One snap. One volume.

ZEISS LSM Lightfield 4D

Investigate the morphology and dynamic movement of developing embryos without compromise. ZEISS Lightfield 4D captures entire 3D volumes in a single snapshot, enabling researchers to follow rapid developmental processes—such as tissue folding, cell migration, and organ formation—with high temporal and spatial resolution. By eliminating the trade-off between imaging speed and volumetric detail, it preserves delicate embryonic structures while delivering quantitative, time-resolved insight into complex biological events as they unfold.

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Lightfield 4D imaging for dynamic, high-speed cell biology

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Simultaneous improvement in speed and resolution

ZEISS LSM Airyscan 2

Investigate vesicular transport in live mammalian cells with the unique combination of gentle illumination, high speed, and super-resolution.

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Live imaging at high spatiotemporal resolution

ZEISS Lattice SIM family

Combine high speed imaging with incredible light efficiency, low photon dosage and sensitivity to observe cellular, subcellular, and even sub-organelle structures in living specimens in 2D and 3D over time. ​

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Long-term live-cell imaging of mitotic waves with minimal phototoxicity

ZEISS Lattice Lightsheet 7

Image mitotic waves in live cells continuously over multiple days while maintaining cell viability and signal integrity. Advanced low-light imaging strategies minimize phototoxic effects and photobleaching, allowing researchers to observe cell cycle progression, spatial coordination of division, and long-term population dynamics with high temporal resolution and quantitative confidence.

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Efficient spectral multiplexing

ZEISS LSM Spectral Multiplex

Unparalleled productivity for your demanding spectral imaging experiments, covering a broad wavelength range from 380 to 900 nm. This extensive spectral coverage enables precise separation of multiple fluorophores, supports complex multiplexing strategies, and allows detection of both visible and near-infrared signals within a single experiment. Advanced spectral detection and unmixing capabilities enhance sensitivity and signal fidelity, helping you extract meaningful biological insights while streamlining acquisition and analysis workflows.

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Add a new dimension to live imaging

ZEISS LSM 910/990

Add a new dimension to live imaging with ZEISS LSM 910 and LSM 990 confocal platforms, designed to capture complex biological dynamics with precision and flexibility. These systems combine high sensitivity detection, advanced spectral capabilities, and gentle imaging modes to support long-term live-cell experiments while preserving sample integrity. From fast intracellular events to large, multidimensional datasets, ZEISS LSM 910/990 enable researchers to visualize, quantify, and interpret biological processes with confidence.

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Advancements in cell biology research

  • Unlike traditional microscopy, lattice light sheet technique allowed us to visualize the viral entry on the entire cell surface. Furthermore, we were able to track IAVs before and after they attach to the cell membrane.

    Dr. Allen Liu University of Michigan

  • Super-resolution microscopy using ZEISS Elyra 7 turned out to be a powerful tool to visualize SARS-CoV-2 viral proteins (through immunofluorescence) and/or RNA (via HuluFISH) in specific cellular compartments, such as membrane or cytosol.

    Dr. Veronica Ferruci University Federico II and CEINGE Biotecnologie Avanzate, Italy

  • With ZEISS Lattice Lightsheet 7 we can visualize the intricate interplay of various molecular markers, but in the context of the whole cell, across a large population of cells. Just the ability to see where and when a protein of interest will be, given a certain stimulus, can inform and direct entire bodies of research.

    Dr Niall Geoghegan Centre for Dynamic Imaging

Solving for the complexity of visualizing dynamic, multidimensional cellular processes with speed, sensitivity, and quantitative precision.

Modern cell biology demands the ability to capture fast dynamics, resolve fine structural detail, and analyze multiple molecular signals simultaneously—often within delicate live samples. ZEISS imaging solutions are designed to address these challenges by combining gentle acquisition modes, advanced spectral detection, and high-speed volumetric imaging with robust analysis workflows. The result is reliable, reproducible data that empowers researchers to uncover deeper insights into cellular structure, function, and development.

  • Unparalleled detail

    Advanced super-resolution microscopy techniques, like Airyscan and Lattice SIM enable imaging at the nanoscale and reveal fine details of cellular components.

  • Versatility and customization

    Modular designs allow researchers to customize their setups with various imaging modalities, like fluorescence, phase contrast and environmental control for live cell imaging.

  • Advanced image analysis

    Integrate machine learning and AI-driven tools for advanced image analysis accuracy and efficiency, so that you can focus on interpretation rather than manual processing.

Comprehensive Solutions and Capabilities

Discover Our Application Hub

Explore applications to discover tailored solutions for your unique laboratory needs and elevate your research capabilities.

Advancing cell biology with high-speed, volumetric imaging

Erapid, high-resolution 3D imaging with the throughput, sensitivity, and quantitative precision required for modern cell biology research.

High-throughput 3D imaging of cardiac regeneration at cellular resolution

Rapid, multi-channel volumetric imaging of cleared heart tissue with ZEISS Lightfield 4D—capturing complete thick sections in minutes, not hours.

Multicolor imaging of stem cell niches in intact tissue

Image fast-spinning, sub-millimeter specimens like Volvox in real time with isotropic volumetric resolution—enabling accurate tracking of morphology, motility, and cellular organization without motion artifacts.

Fast, high-resolution 3D imaging of complex epithelial structures

Capture large, multicolor volumetric datasets in seconds—achieving precise cellular localization across wide areas without compromising axial accuracy or throughput.

Capture rapid 4D dynamics in living multicellular organisms

Image fast-spinning, sub-millimeter specimens like Volvox in real time with isotropic volumetric resolution—enabling accurate tracking of morphology, motility, and cellular organization without motion artifacts.