ZEISS Crossbeam Samplefab FIB-SEM system for automated TEM lamella preparation and high-throughput sample workflows.

ZEISS Crossbeam Samplefab FIB-SEM

Hands-free TEM lamella automation for uniformity and reliability

ZEISS Crossbeam Samplefab is a preconfigured automation platform for high-throughput TEM lamella preparation. Built for semiconductor production yield analysis and high-volume research, it delivers unattended workflows with qualification-supported results, achieving greater than 90 percent success from bulk material to grid. The result is consistent with lamella quality, full traceability, and uniform output across shifts, operators, and sites.

  • Qualified automation yield exceeding 90 percent from chunking to grid attachment
  • Fully hands-free bulk-to-grid processing with recipe-based workflows
  • Low-kV finishing for uniform lamella thickness and quality
  • Complete traceability with logged processes and reusable recipes
  • Optimized for production environments and multi-site labs

ZEISS Crossbeam Samplefab automated FIB-SEM system designed for high-throughput TEM lamella preparation.

What’s different about Crossbeam Samplefab

New recipe-based automation now spans the full bulk-to-grid workflow, including chunking, lift-out, and grid attachment. By removing manual steps, Crossbeam Samplefab ensures consistent, high-quality lamella preparation at production scale, reducing variability and increasing efficiency.

Illustration of focused ion beam milling used to prepare thin TEM lamellae for analysis with the ZEISS Crossbeam 550  Samplefab FIB-SEM.

Key specifications

  • Dedicated automation platform: Preconfigured specifically for TEM prep
  • Batch execution: Process multiple lamellae across multiple samples simultaneously
  • Traceability: Full logging and recipe reuse for standardized workflows
  • Manual flexibility: Optional fine polishing on any Crossbeam
SEM image of a device region prepared for TEM lamella extraction using ZEISS Crossbeam Samplefab.

Integrated TEM lamella preparation & imaging workflows

ZEISS Crossbeam Samplefab supports standardized, high-throughput TEM lamella preparation from bulk material to grid attachment. Recipe-driven workflows and consistent low-energy finishing ensure predictable lamella thickness across large batches. This enables reliable device characterization, yield engineering, and process control with repeatable outcomes, even in demanding production environments.

ZEISS software interface supporting automated TEM lamella preparation and high-throughput FIB-SEM workflows.

Software workflows built for high-throughput sample preparation

ZEISS Efficient Navigation (ZEN) software enables efficient, standardized Crossbeam Samplefab workflows from setup to execution. ZEN core EM supports automated recipes, batch processing, and synchronized SEM/FIB operations to minimize user variability and maximize throughput. Extending core control, the ZEISS arivis ecosystem enables scalable image analysis for high-volume datasets, supporting consistent evaluation, documentation, and downstream workflows. Together, these tools help teams scale TEM sample preparation and production to maintain audit-readiness at full automation scale with reliable, repeatable results.

Related applications

SEM image showing an array of 7×6 silicon lamella chunks prepared for TEM using the ZEN TEM Prep module in ZEN core.

SEM image showing an array of 7×6 silicon lamella chunks prepared for TEM using the ZEN TEM Prep module in ZEN core.

SEM image showing an array of 7×6 silicon lamella chunks prepared for TEM using the ZEN TEM Prep module in ZEN core.

Electronics & Semiconductor Analysis

  • Prepare consistent, low-damage lamellae from transistor gate stacks, vias, contacts, and BEOL/FEOL layers
  • Process defects with precise endpointing and low-kV finishing
  • Standardize preparation for yield engineering, device characterization, and failure analysis

Services & support

Expertise built around automated, high-volume workflows

ZEISS supports Crossbeam Samplefab with service and application expertise aligned to automated, high-throughput TEM lamella production. Specialists assist with workflow setup, recipe optimization, and integration into production or process control environments. Comprehensive service agreements and proactive support help maintain consistency, yield, and system availability in demanding operational settings.

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FAQ

  • ZEISS Crossbeam Samplefab is designed to standardize and scale repetitive FIB sample-preparation tasks, reducing operator dependence and increasing throughput in production, service, and shared-facility environments. By automating the bulk-to-grid workflow, Crossbeam Samplefab ensures consistent lamella quality and reliable results across shifts, operators, and sites.

  • Crossbeam Samplefab prioritizes automation and reproducibility over flexibility. Unlike other Crossbeam models, it delivers fully hands-free, recipe-based workflows for high-throughput TEM lamella preparation. This makes Crossbeam Samplefab ideal for environments where consistency and scalability are critical, such as semiconductor production and yield engineering

  • Crossbeam Samplefab is best suited for repetitive workflows such as TEM lamella preparation, routine cross-sectioning, and standardized FIB processes where consistency and throughput are critical.

  • No. Crossbeam Samplefab is primarily optimized for standardized, repeatable preparation rather than exploratory or frequently changing workflows. However, Crossbeam Samplefab can support exploratory recipe development by allowing users to set up different recipes for each preparation site. This enables testing and evaluation of optimal conditions for specific material compositions before standardizing workflows.

  • Software is central to Crossbeam Samplefab’s automation and efficiency. ZEN core EM integrates SEM and FIB control within a single environment, supporting recipe-based workflows, batch execution, and synchronized imaging during milling. For downstream analysis, the ZEISS arivis ecosystem enables scalable visualization, segmentation, and quantitative analysis of complex datasets, ensuring consistent evaluation and documentation.

  • Crossbeam Samplefab delivers qualified automation yields exceeding 90 percent, from chunking to grid attachment. This high success rate is achieved through hands-free processing, low-kV finishing, and recipe-driven workflows that minimize user intervention. The system prioritizes device safety first and sample quality second, ensuring that critical device layers remain intact during preparation. User intervention is only prompted when necessary, further enhancing reliability and reproducibility across workflows.

  • Yes. Crossbeam Samplefab is designed to handle beam-sensitive materials with care, utilizing low-energy FIB finishing and low-kV SEM imaging to reduce damage and preserve fine structural details. This ensures reliable preparation of delicate samples, including thin films, polymers, and intricate semiconductor structures.