Pubblicazioni sull’uso dell’acido 5-aminolevulinico (5-ALA) nella chirurgia guidata dalla fluorescenza

Comparative analysis of clinical outcomes in high-grade glioma patients: 5-ALA fluorescence-guided surgery vs. conventional white-light resection
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Articolo originale (retrospettivo, monocentrico, n=141)

Cancers

Ryskeldiyev N, Moldabekov A, Berdibayeva D, Maidan A, Tursynbekov T, Davletov D, Tleubergenov M, Kabykenova A, Kerimbayeva D, Doskaliyev A, Akshulakov S

Comparative analysis of 5-ALA and fluorescent techniques in high-grade glioma treatment
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Revisione sistematica

Biomedicines

Valerio JE, de Jesús Aguirre Vera G, Zumaeta J, Rea NS, Fernandez Gomez MP, Mantilla-Farfan P, Valente L, Alvarez-Pinzon AM

Predicting intraoperative 5‑ALA‑induced tumor fluorescence via MRI and deep learning in gliomas with radiographic lower‑grade characteristics
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Articolo originale (retrospettivo, monocentrico, n=163)

Journal of Neuro-Oncology

Suero Molina E, Azemi G, Özdemir Z, Russo C, Krähling H, Valls Chavarria A, Liu S, Stummer W, Di Ieva A

Intraoperative MRI-guided resection is not superior to 5-aminolevulinic acid guidance in newly diagnosed glioblastoma: a prospective controlled multicenter clinical trial
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Articolo originale (retrospettivo, monocentrico, n=314)

Journal of Clinical Oncology

Roder C, Stummer W, Coburger J, Scherer M, Haas P, von der Brelie C, Kamp MA, Löhr M, Hamisch CA, Skardelly M, Scholz T, Schipmann S, Rathert J, Brand CM, Pala A, Ernemann U, Stockhammer F, Gerlach R, Kremer P, Goldbrunner R, Ernestus RI, Sabel M, Rohde V, Tabatabai G, Martus P, Bisdas S, Ganslandt O, Unterberg A, Wirtz CR, Tatagiba M

Second-generation wide-field visualization devices for 5-ALA-induced fluorescence and concepts for validation in neurosurgery - a systematic review
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Revisione sistematica

Neurosurgery Practice

Özdemir Z, Suero Molina E, Hellwig SJ, Stepp H, Stummer W

Use of 5-ALA fluorescence-guided surgery versus white-light conventional microsurgery for the resection of newly diagnosed glioblastomas (RESECT study): a french multicenter randomized phase III study
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Articolo originale (retrospettivo, monocentrico, n=171)

Journal of Neurosurgery

Picart T, Pallud J, Berthiller J, Dumot C, Berhouma M, Ducray F, Armoiry X, Margier J, Guerre P, Varlet P, Meyronet D, Metellus P, Guyotat J

How reliable is fluorescence-guided surgery in low-grade gliomas? A systematic review concerning different fluorophores
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Revisione sistematica

Cancers

Bianconi A, Bonada M, Zeppa P, Colonna S, Tartara F, Melcarne A, Garbossa D, Cofano F

Turning on the light for brain tumor surgery: a 5-aminolevulinic acid story
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Revisione

Neuro-Oncology

McCracken DJ, Schupper AJ, Lakomkin N, Malcolm J, Painton Bray D, Hadjipanayis CG

5-ALA-guided tumor resection during awake speech mapping in gliomas located in eloquent speech areas: single-center experience
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Articolo originale (retrospettivo, monocentrico, n=28)

Frontiers in Oncology

Goryaynov SA, Buklina SB, Khapov IV, Batalov AI, Potapov AA, Pronin IN, Belyaev AU, Aristov AA, Zhukov VU, Pavlova GV, Belykh E

5-Aminolevulinic acid and sodium fluorescein in IV ventricle ependymoma surgery: preliminary experience comparing the two techniques
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Articolo originale (retrospettivo, monocentrico, n=6)

Neurosurgical Sciences

"Boschi A, Lastrucci G, Pisano A, Becattini E, Buccoliero A, Della
Puppa A."

Effect of 5-aminolevulinic acid and sodium fluorescein on the extent of resection in high-grade gliomas and brain metastasis
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Revisione

Cancers

Ahrens LC, Krabbenhøft MG, Hansen RW, Mikic N, Pedersen CB, Poulsen FR, Korshoej AR

Intraoperative 5-ALA fluorescence-guided resection of high-grade glioma leads to greater extent of resection with better outcomes: a systematic review
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Revisione sistematica

Journal of Neuro-Oncology

Eatz TA, Eichberg DG, Lu VM, Di L, Komotar RJ, Ivan ME

5-Aminolevulinic acid for enhanced surgical visualization of high-grade gliomas: a prospective, multicenter study
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Articolo originale (prospettico, multicentrico, n=69)

Journal of Neurosurgery

Schupper AJ, Baron RB, Cheung W, Rodriguez J, Kalkanis SN, Chohan MO, Andersen BJ, Chamoun R, Nahed BV, Zacharia BE, Kennedy J, Moulding HD, Zucker L, Chicoine MR, Olson JJ, Jensen RL, Sherman JH, Zhang X, Price G, Fowkes M, Germano IM, Carter BS, Hadjipanayis CG, Yong RL

5-ALA in suspected low-grade gliomas: current role, limitations, and new approaches
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Revisione

Frontiers in Oncology

Kiesel B, Freund J, Reichert D, Wadiura L, Erkkilae MT, Woehrer A, Hervey-Jumper S, Berger MS, Widhalm G

5-ALA fluorescence for intraoperative visualization of spinal ependymal tumors and identification of unexpected residual tumor tissue: experience in 31 patients
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Articolo originale (monocentrico, n=31)

Journal of Neurosurgery: Colonna vertebrale

Millesi M, Kiesel B, Mazanec V, Wadiura LI, Wöhrer A, Herta J, Wolfsberger S, Novak K, Furtner J, Rössler K, Knosp E, Widhalm G

Validating a new generation filter system for visualizing 5-ALA-induced PpIX fluorescence in malignant glioma surgery: a proof of principle study
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Articolo originale (prospettico, monocentrico, n=32)

Acta Neurochirurgica

Suero Molina E, Stögbauer L, Jeibmann A, Warneke N, Stummer W

Comparison of 5-aminolevulinic acid and sodium fluorescein for intraoperative tumor visualization in patients with high-grade gliomas: a single-center retrospective study
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Articolo originale (retrospettivo, monocentrico, n=209)

Journal of Neurosurgery

Hansen RW, Pedersen CB, Halle B, Korshoej AR, Schulz MK, Kristensen BW, Poulsen FR

Fluorescence diagnosis in neurooncology: retrospective analysis of 653 cases
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Articolo originale (retrospettivo, multicentrico, n=641)

Frontiers in Oncology

Goryaynov SA, Okhlopkov VA, Golbin DA, Chernyshov KA, Svistov DV, Martynov BV, Kim AV, Byvaltsev VA, Pavlova GV, Batalov A, Konovalov NA, Zelenkov PV, Loschenov VB, Potapov AA

5-ALA complete resections go beyond MR contrast enhancement: shift corrected volumetric analysis of the extent of resection in surgery for glioblastoma
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Articolo originale (retrospettivo, monocentrico, n=13)

Acta Neurochirurgica

Schucht P, Knittel S, Slotboom J, Seidel K, Murek M, Jilch A, Raabe A, Beck J

Fluorescence-guided surgery for resection of malignant glioma: a randomized controlled multicentre phase III trial
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Articolo originale (multicentrico, n=270)

The Lancet Oncology

Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ

Fluorescence-guided surgery using 5-aminolevulinic acid/protoporphyrin IX in brain metastases
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Revisione sistematica e meta-analisi

Neurosurgery Practice

Price A, Bernstock JD, Truong N, Wu K, Lee JYK, Tucker IJ, Gessler F, DeSena S, Friedman G, Valdes PA

Does 5-ALA fluorescence microscopy improve complete resectability in cerebral/cerebellar metastatic surgery? A retrospective data analysis from a cranial center
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Articolo originale (retrospettivo, monocentrico, n=73)

Cancers (Basel)

Sarkis HM, Zawy Alsofy S, Stroop R, Lewitz M, Schipmann S, Unnewehr M, Paulus W, Nakamura M, Ewelt C

Utility of 5-ALA for fluorescence-guided resection of brain metastases: a systematic review
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Revisione sistematica

Journal of Neuro-Oncology

Shah HA, Leskinen S, Khilji H, Narayan V, Ben-Shalom N, D’Amico RS

Significance of 5-ALA-guided fluorescence in resection of invasive intracranial meningiomas: findings from a prospective clinical study
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Articolo originale (prospettico, monocentrico, n=13)

Cancers (Basel)

Matsuda M, Sugii N, Sakamoto N, Yamano A, Ishikawa E

Fluorescence guidance in skull base surgery: applications and limitations - a systematic review
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Revisione sistematica

Brain and Spine

Suero Molina E, Bruneau M, Reuter G, Shahein M, Cavallo LM, Daniel RT, Kasper EM, Froelich S, Jouanneau E, Manet R, Messerer M, Mazzatenta D, Meling TR, Roche PH, Schroeder HW, Tatagiba M, Visocchi M, Prevedello DM, Stummer W, Cornelius JF

Protoporphyrin IX (PpIX) fluorescence during meningioma surgery: correlations with histological findings and expression of heme pathway molecules
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Articolo originale (monocentrico, n=44)

Cancers (Basel)

Spille DC, Bunk EC, Thomas C, Özdemir Z, Wagner A, Akkurt BH, Mannil M, Paulus W, Grauer OM, Stummer W, Senner V, Brokinkel B

5-Aminolevulinic acid (5-ALA) in paediatric brain tumour surgery - a systematic review and exploration of fluorophore alternatives
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Revisione sistematica

Child’s Nervous System

Collins VG, Kanodia C, Yahya QB, Liistro M, Kaliaperumal C

Analysis of 5-aminolevulinic acid-induced fluorescence in 55 different spinal tumors
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Articolo originale (prospettico, monocentrico, n=52)

Neurosurgical Focus

Millesi M, Kiesel B, Woehrer A, Hainfellner JA, Novak K, Martínez-Moreno M, Wolfsberger S, Knosp E, Widhalm G

Sodium fluorescein and 5-aminolevulinic acid fluorescence-guided biopsy in brain lesions: a systematic review and meta-analysis
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Revisione sistematica e meta-analisi

Journal of Neuro-Oncology

Gomes FC, Ferreira MY, Larcipretti ALL, Freitas BCB, Andreão FF, Turpin J, Bertani R, Singha S, Polverini AD, Ferreira C, Dellaretti M, D’Amico RS

5-ALA-induced fluorescence as a marker for diagnostic tissue in stereotactic biopsies of intracranial lymphomas: experience in 41 patients
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Articolo originale (prospettico, monocentrico, n=41)

Neurosurgical Focus

Kiesel B, Millesi M, Woehrer A, Furtner J, Bavand A, Roetzer T, Mischkulnig M, Wolfsberger S, Preusser M, Knosp E, Widhalm G

Current and future applications of 5-aminolevulinic acid in neurosurgical oncology
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Revisione

Cancers

Chen JS, Young JS, Berger MS

Enlightening the invisible: applications, limits and perspectives of intraoperative fluorescence in neurosurgery
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Revisione

Brain and Spine

Cossu G, Le Van T, Kerherve L, Houidi SA, Morlaix E, Bonneville F, Chapon R, Baland O, Cao C, Lleu M, Farah W, El Cadhi A, Beaurain J, Picart T, Xu B, Berhouma M

Fluorescence-guided surgical techniques in adult diffuse low-grade gliomas: state-of-the-art and emerging techniques: a systematic review
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Revisione sistematica

Cancers (Basel)

Picart T, Gautheron A, Caredda C, Ray C, Mahieu-Williame L, Montcel B, Guyotat J

Effect of 5-aminolevulinic acid and sodium fluorescein on the extent of resection in high-grade gliomas and brain metastasis
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Revisione

Cancers (Basel)

Ahrens LC, Krabbenhøft MG, Hansen RW, Mikic N, Pedersen CB, Poulsen FR, Korshoej AR

Fluorescence-guided surgery: a review on timing and use in brain tumor surgery
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Revisione

Frontiers in Neurology

Schupper AJ, Rao M, Mohammadi N, Baron R, Lee JYK, Acerbi F, Hadjipanayis CG