Human-Distal-Lung-Organoid
3D TISSUE MODELS WEBINAR SERIES

Imaging of Complex In-Vitro Models

Unlocking Predictive Insights for Drug Discovery and Development
  • Session 1: Overcoming Imaging Depth and Throughput Challenges in 3D Breast Cancer Organoids | December 11, 2025
  • Session 2: Fast and Gentle Imaging of Developing Human Spinal Cord Organoids with ZEISS Lattice Lightsheet 7 | January 20, 2026
  • Session 3: Deep Imaging and Scalable Analysis of Hepatic Spheroids with ZEISS LSM 910/980 Lightfield 4D | February 17, 2026
Session 1 | December 11, Thursday - 9AM - 9:30AM CET

Overcoming Imaging Depth and Throughput Challenges in 3D Breast Cancer Organoids

Dense and heterogeneous 3D tissue models such as breast cancer organoids in Matrigel pose significant imaging challenges, from light scattering and limited penetration depth to maintaining gentle conditions for live samples during long-term imaging.

Join us to discover how the ZEISS Celldiscoverer 7 with LSM and Airyscan technologies, combined with the arivis analysis suite, enable deep, high-resolution, and high-throughput imaging of complex organoid models.
You will see how this integrated workflow optimizes acquisition parameters for both depth and speed, while preserving cellular integrity, and how AI-driven analysis in arivis Cloud simplifies segmentation, quantification, and scaling to larger datasets across experiments.

Participants will:

  • Explore how ZEISS Celldiscoverer 7 with LSM/Airyscan enables deep, high-resolution imaging through dense matrices like Matrigel.
  • Learn strategies for maintaining gentle illumination and improving sensitivity during long-term organoid imaging.
  • Discover how the arivis platform simplifies 3D organoid analysis and scales effortlessly from single samples to high-throughput studies.
  • See how automation and AI-based segmentation accelerate data interpretation and reproducibility in large-scale cancer research.
Session 2 | January 20, Tuesday - 10AM - 10:30 AM CET

Fast and Gentle Imaging of Developing Human Spinal Cord Organoids with ZEISS Lattice Lightsheet 7

Capturing the rapid and complex dynamics of developing neural organoids requires exceptional resolution, speed, and minimal phototoxicity. Traditional confocal imaging often struggles to meet these demands in thick, scattering media such as Matrigel.In this session, learn how the ZEISS Lattice Lightsheet 7, combined with arivis AI-powered analysis, overcomes these limitations, offering fast, gentle, and high-resolution volumetric imaging of human embryonic stem cell-derived spinal cord organoids.

You will also discover how the arivis Cloud and Hub streamline data management and collaborative analysis for large, multi-sample experiments, unlocking new insights into neural development and tissue organization at scale.

Participants will:

  • Discover how Lattice Lightsheet 7 enables rapid, high-resolution, and phototoxicity-free imaging of 3D organoids.
  • Learn how to capture complex developmental processes in real time without compromising cell health.
  • See how arivis Cloud accelerates segmentation and quantitative analysis of intricate neural structures.
  • Understand how scalable data handling in arivis Hub supports large-volume and longitudinal organoid imaging projects.
Session 3 | February 17, Tuesday - 9AM - 9:30AM CET

Deep Imaging and Scalable Analysis of Hepatic Spheroids with ZEISS LSM 910/980 Lightfield 4D

Three-dimensional hepatic spheroids represent a physiologically relevant model for drug discovery and toxicology, but their dense hydrogel embedding presents imaging challenges, especially for achieving depth, sensitivity, and speed at scale.

Join us to explore how the ZEISS LSM 910/980 with Lightfield 4D detection, in combination with the arivis analysis ecosystem, enables fast and gentle volumetric imaging through scattering tissues.
Learn how the workflow supports high-throughput acquisition, efficient data management, and AI-assisted segmentation, empowering researchers to scale from single spheroids to entire plate-based screening workflows without compromising image quality or analytical consistency.

Participants will:

  • Experience how Lightfield 4D detection delivers high-sensitivity, depth-optimized imaging for dense 3D spheroid samples.
  • Learn how to accelerate imaging throughput across multiple samples or screening plates.
  • Discover how arivis software handles large 4D datasets seamlessly on standard workstations.
  • Explore automated segmentation and scalable analysis through arivis Cloud and Hub for robust, reproducible insights in liver model research.

Register now!

Session 1 | December 11, Thursday - 9AM - 9:30AM CET

Overcoming Imaging Depth and Throughput Challenges in 3D Breast Cancer Organoids

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Session 2 | January 20, Tuesday - 10AM - 10:30 AM CET

Fast and Gentle Imaging of Developing Human Spinal Cord Organoids with ZEISS Lattice Lightsheet 7

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February 17, Tuesday - 9AM - 9:30AM CET

Deep Imaging and Scalable Analysis of Hepatic Spheroids with ZEISS LSM 910/980 Lightfield 4D

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If you want to have more information on data processing at ZEISS please refer to our data privacy notice.