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用于样品制备的显微镜解决方案
适用于遗传研究等进一步检查
发育生物学、分子生物学、胚胎学、植物科学和神经生物学等众多学科均采用模式生物进行研究，通常需要在进入遗传研究等进一步检查前接收特殊处理或制备。
秀丽隐杆线虫、斑马鱼和黑腹果蝇分别广泛地用于蠕虫实验室、斑马鱼实验室和果蝇实验室。这些模式生物需要在其发育阶段（如卵、胚胎、幼虫等）进行常规分类、挑选、计数、操作、解剖、成像和监测。体视或解剖显微镜是完成这些任务不可或缺的工具。
模式生物可以是细菌、真菌、植物或动物。理想情况下，模式生物应表现出某些特征：
- 与人类共享众多基因
- 体积小巧，易于在实验室中生长
- 先天性状明显
- 测序基因组可用
- 基因操作简单
- 遗传易处理
- 世代时间和生命周期短
常见模式生物示例
-
秀丽隐杆状线虫生殖系。
黑腹果蝇
斑马鱼
非洲爪蟾、热带爪蟾
研究领域• 发育生物学
• 分子生物学
• 生理学
• 药理学
• 毒理学• 遗传学
• 发育生物学
• 神经科学• 胚胎学
• 发育生物学
• 分子生物学
• 毒理学
• 神经生物学• 胚胎学
• 发育生物学
• 细胞生物学
• 神经生物学特征• 整个生命周期保持透明
• 世代时间短（3天
• 易于操作• 易于生长和维护
• 世代时间短（8-14天）
• 4对染色体
• 易于操作• 与人类共享70%的基因
• 易于繁殖
• 透明
• 易于操作• 胚胎易于获取
• 具有10000个卵母细胞
• 卵母细胞/胚胎大
• 易于操作 -
小家鼠
褐家鼠
蝾螈
拟南芥
研究领域• 神经生物学
• 遗传学
• 基因组学
• 制药
• 临床研究• 神经科学
• 毒理学
• 遗传学
• 基因组学
• 生理学• 再生医学
• 发育生物学• 发育生物学
• 细胞生物学
• 分子生物学
• 遗传学
• 植物生理学特征• 时代时间相对较短（约10周）
• 与人类99%同系
• 疾病模型
• 遗传易处理
• 易于操作• 疾病模型
• 初级神经元来源
• 器官较大可以再生其
• 尾巴
• 四肢
• 部分大脑等• 小基因组
• 5对染色体
• 许多突变体
• 易于操作
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对显微镜的要求
体视显微镜有两种类型：Greenough型和共用主物镜（CMO）型，每种都有其独特特点。CMO型与Greenough型相比具有某些优势，特别是在照明、荧光功能、数字图像记录和人体工程学方面。但Greenough型体视显微镜更紧凑、高度集成且价格实惠。
三维立体视图结合了大范围的自由工作距离和符合人体工程学的功能，可为科学家和技术人员的日常研究工作提供有力支持。这些显微镜非常适合机械操作、分类和一般样品制备。在使用绿色（GFP）或红色（RFP）荧光蛋白等标记的转基因研究中，也会优先采用体视或变焦显微镜来进行修饰基因型的荧光筛选（如通过CRISPR/Cas9介导的突变）。您可以结合大观察视野与高分辨率，显著加快研究过程。
解剖显微镜也普遍用于神经科学研究，例如在处理大鼠等较大的脊椎动物时，它们通常用于获取原代细胞培养物。
应用实例
![秀丽隐杆线虫，反射光明场。使用蔡司Stemi 508成像。]({"xsmall":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/c-elegans_stemi-508.jpg/_jcr_content/renditions/original.image_file.100.75.file/c-elegans_stemi-508.jpg","small":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/c-elegans_stemi-508.jpg/_jcr_content/renditions/original.image_file.360.270.file/c-elegans_stemi-508.jpg","medium":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/c-elegans_stemi-508.jpg/_jcr_content/renditions/original.image_file.768.576.file/c-elegans_stemi-508.jpg","large":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/c-elegans_stemi-508.jpg/_jcr_content/renditions/original.image_file.1024.768.file/c-elegans_stemi-508.jpg","xlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/c-elegans_stemi-508.jpg/_jcr_content/renditions/original.image_file.1280.960.file/c-elegans_stemi-508.jpg","xxlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/c-elegans_stemi-508.jpg/_jcr_content/renditions/original.image_file.1440.1080.file/c-elegans_stemi-508.jpg","max":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/c-elegans_stemi-508.jpg/_jcr_content/renditions/original./c-elegans_stemi-508.jpg"} "秀丽隐杆线虫，反射光明场。使用蔡司Stemi 508成像。")
![斑马鱼胚胎尾巴，斜透射光。使用蔡司Stemi 508成像。]({"xsmall":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/transmitted-light_zebrafish-tail_stemi-508.jpg/_jcr_content/renditions/original.image_file.100.75.file/transmitted-light_zebrafish-tail_stemi-508.jpg","small":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/transmitted-light_zebrafish-tail_stemi-508.jpg/_jcr_content/renditions/original.image_file.360.270.file/transmitted-light_zebrafish-tail_stemi-508.jpg","medium":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/transmitted-light_zebrafish-tail_stemi-508.jpg/_jcr_content/renditions/original.image_file.768.576.file/transmitted-light_zebrafish-tail_stemi-508.jpg","large":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/transmitted-light_zebrafish-tail_stemi-508.jpg/_jcr_content/renditions/original.image_file.1024.768.file/transmitted-light_zebrafish-tail_stemi-508.jpg","xlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/transmitted-light_zebrafish-tail_stemi-508.jpg/_jcr_content/renditions/original.image_file.1280.960.file/transmitted-light_zebrafish-tail_stemi-508.jpg","xxlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/transmitted-light_zebrafish-tail_stemi-508.jpg/_jcr_content/renditions/original.image_file.1440.1080.file/transmitted-light_zebrafish-tail_stemi-508.jpg","max":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/transmitted-light_zebrafish-tail_stemi-508.jpg/_jcr_content/renditions/original./transmitted-light_zebrafish-tail_stemi-508.jpg"} "斑马鱼胚胎尾巴，斜透射光。使用蔡司Stemi 508成像。")
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![蜘蛛蟹胚胎，透射光暗场。使用蔡司Stemi 508成像]({"xsmall":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/darkfield_crab-embryos_stemi-2000.jpg/_jcr_content/renditions/original.image_file.100.75.file/darkfield_crab-embryos_stemi-2000.jpg","small":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/darkfield_crab-embryos_stemi-2000.jpg/_jcr_content/renditions/original.image_file.360.270.file/darkfield_crab-embryos_stemi-2000.jpg","medium":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/darkfield_crab-embryos_stemi-2000.jpg/_jcr_content/renditions/original.image_file.768.576.file/darkfield_crab-embryos_stemi-2000.jpg","large":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/darkfield_crab-embryos_stemi-2000.jpg/_jcr_content/renditions/original.image_file.1024.768.file/darkfield_crab-embryos_stemi-2000.jpg","xlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/darkfield_crab-embryos_stemi-2000.jpg/_jcr_content/renditions/original.image_file.1280.960.file/darkfield_crab-embryos_stemi-2000.jpg","xxlarge":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/darkfield_crab-embryos_stemi-2000.jpg/_jcr_content/renditions/original.image_file.1440.1080.file/darkfield_crab-embryos_stemi-2000.jpg","max":"https://www.zeiss.com/content/dam/rms/reference-master/applications/laboratory-and-routine/clinical-laboratory/sample-preparation/darkfield_crab-embryos_stemi-2000.jpg/_jcr_content/renditions/original./darkfield_crab-embryos_stemi-2000.jpg"} "蜘蛛蟹胚胎，透射光暗场。使用蔡司Stemi 508成像")
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Microscopic Anatomy in the Study of Medicine
Fundamentals of Histology
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