
ZEISS Axiocam 506 mono
6 Megapixel Microscope Camera for Fast and Sensitive Live Cell Imaging
This flexible 6 megapixel microscope camera is a true allrounder. It produces a high quality and rapid live image as well as the highest level of sensitivity for low-light and live cell imaging. Its high sensitivity enables you to use short exposure times, even with weak fluorescent markers, preventing damage to your samples. You can increase sensitivity through pixel binning – and still have enough resolution for optimal imaging.
The camera’s 1” sensor combines with the large number of pixels to give you a field of view twice as large as that of 2/3” cameras. You will always have a good overview of your sample. Optional synchronization of other components by hardware trigger signals assures reproducible imaging precision.


SK8 / K18 cells, staining: intermediate filaments labeled tagged with GFP (green), Tubulin Antibody label (red), DAPI (blue), acquired with ZEISS Axio Imager, objective: EC Plan-NEOFLUAR 40× / 0.7
ZEISS Axiocam 506 mono is Recommended for
- Live cell imaging
- High-resolution fluorescence imaging
- Fluorescence scanning applications
- Near Infrared fluorescence dyes
- Near Infrared observation in materials applications
Caption: SK8 / K18 cells, staining: intermediate filaments labeled tagged with GFP (green), Tubulin Antibody label (red), DAPI (blue), acquired with ZEISS Axio Imager, objective: EC Plan-NEOFLUAR 40× / 0.7


Quantum efficiency
Quantum efficiency
Highlights of Axiocam 506 mono
- 6 megapixel CCD sensor
- Excellent coverage of the microscopic field of view and sample overview, thanks to the 1” sensor – twice the field of view compared to 2/3” cameras
- USB 3.0 interface technology with fast 5 gigabit data transfer rate and qad-port, high-end CCD sensor technology for rapid frame rates
- 2752 horizontal pixels × 2208 vertical pixels gives high resolution, even when using pixel binning
- Up to 56 fps with binning 5 × 5
- Expanded area of application for high-aperture and low-magnification objectives, thanks to 4.54 μm small pixel structures – highest resolution with a large field of view
- Thermo electrical cooled sensor
- Optional hardware trigger synchronization
Application Examples

HeLa cells

Staining: Tubulin Alexa 488 (green), pHistone 3 – Alexa 568 (red), Hoechst 33342 (blue), acquired with ZEISS Axio Imager, objective: Plan-APOCHROMAT 40× / 1.4
HeLa cells
Staining: Tubulin Alexa 488 (green), pHistone 3 – Alexa 568 (red), Hoechst 33342 (blue), acquired with ZEISS Axio Imager, objective: Plan-APOCHROMAT 40× / 1.4

Mouse kidney section

Imaged with Axiocam 506 mono and ZEISS Apotome on ZEISS Axio Imager 2.
Mouse kidney section
Imaged with Axiocam 506 mono and ZEISS Apotome on ZEISS Axio Imager 2