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ZEISS OVDs
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ZEISS OVD Portfolio

The power of choice at every step

Based on 20+ years experience, development and production, ZEISS provides a state-of-the-art ophthalmic viscosurgical devices (OVD) portfolio that supports your work at each step of the ophthalmic procedure. ZEISS OVDs originate from bacterial fermentation.1

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Product overview

Select a category
Overall comforter
Multitalents
Protecting layers
Space creators
Economic solutions
ZEISS OVDs VISTHESIA and VISTHESIA intra

ZEISS VISTHESIA® intra / VISTHESIA²

More comfort through pain relief even in prolonged surgery.

Preoperative topical ampules containing sodium hyaluronate (0.3%) with lidocaine (2%) that coats and hydrates the epithelial cells supporting clear vision into the eye.

Intracameral viscous-cohesive OVD

  • Containing sodium hyaluronate in a concentration of 1% and 1.5%, both with lidocaine (1%)
  • Effective space creation and maintenance in the anterior chamber
  • Ensuring even dispersion of lidocaine throughout the eye to all tissues
  • Providing endothelial protection3 and pupil dilation4
  • 2-in-1 solution saving time and preparation steps, since a separate intracameral anesthetic is not required
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ZEISS COMBIVISC®

The perfect match of two OVDs for the entire surgery

Providing the optimal combination of a viscous-cohesive and a medium-viscosity dispersive OVD in two separate syringes. Giving you the space and protection you need in standard and complex cases – with fast and easy removal.

Cohesive part (incl. Z-HYALIN®plus)

  • Highly effective for space creation and maintenance in the anterior chamber5
  • Good capsular bag inflation
  • Optimal chamber retention
  • Ease of injection5
  • Fast and easy removal6

Dispersive part (incl. Z-HYALCOAT®)

  • Reliable protection of the endothelium during various surgical maneuvers
  • Great space partition
  • Excellent optical clarity7
  • Ease of injection
  • Short aspiration time6
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ZEISS TWINVISC®

Two OVDs, one device for each stage of the surgery

Combining a medium-viscosity dispersive and a viscous-cohesive viscoelastic in one syringe separated by an innovative bypass stopper system for a planned sequential injection. Providing an easy and unique approach to the soft-shell-technique.8

  • Reliable protection of the endothelium and other tissues during various surgical maneuvers
  • Highly effective space creation and maintenance in the anterior chamber during IOL implantation8
  • Great retention during phacoemulsification9
  • Excellent optical clarity9
  • Ease of injection
  • Fast and easy removal9
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ZEISS Z-CELCOAT®

Low-viscosity dispersive OVD - providing protection in surgery
  • Protection of the endothelium through coated ocular tissues during various surgical maneuvers10
  • Good space partition
  • Well suited as lubricant for intraocular lenses and instruments
  • Available in large volume syringe (2.1 ml)
  • Multipack option (pack of 10 pc)
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ZEISS Z-HYALCOAT

Medium-viscosity dispersive OVD - a safeguard in surgery
  • Reliable protection of the endothelium during various surgical maneuvers
  • Great space partition
  • Excellent optical clarity7
  • Short aspiration time6
  • Available in large volume syringe (0.85 ml)
  • Multipack option (pack of 10 pc)
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Z-HYALON is only available in EMEA

ZEISS Z-HYALIN®, ZEISS Z-HYALIN plus, ZEISS Z-HYALON®

Viscous-cohesive OVDs – with versatility in surgery
  • Varying effectiveness of space creation and maintenance in the anterior chamber as a result of increases in molecular weight
  • Good to very good capsular bag inflation
  • Optimal chamber retention
  • Smooth injection
  • Fast and easy removal
  • Available in high volume syringes (1 ml, 1 ml, 0.55 ml / 0.85 ml)
  • Multipack option (pack of 10 pc)15
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Z-HYALON plus is only available in EMEA

ZEISS Z-HYALON® plus

Super-viscous cohesive OVD - reliability and efficiency in challenging cases
  • Provides maximum intraocular stability with excellent space creation and maintenance due to super high molecular weight
  • Very good capsular bag inflation
  • Faster and easier removal as a single mass
  • Very easy injection
  • Optimal optical clarity
  • Smaller, space-saving packaging and storage at room temperature for efficiency.16
  • Available in 0.55 and 0.85ml syringe volumes
Compare product properties

ZEISS Multipack

Your favorite box of ten

ZEISS OVDs available in 10 syringe multipacks:

  • COMBIVISC (pack of 5 pairs)
  • Z-CELCOAT
  • Z-HYALCOAT
  • Z-HYALIN
  • Z-HYALIN plus

Powerful as individual solution – Unstoppable together

The new ZEISS Cataract Workflow

By connecting devices, data and applications, the ZEISS portfolio enables a seamless integration from office to OR and back.

Learn more about the ZEISS Cataract Workflow

Product comparison

  • Classification
    Single pack content
    Multipack content
    Origin
    Volume (ml)
    Substance
    Concentration I (%)
    Concentration II (mg/ml)
    VISTHESIA 1.0%
    Viscous-cohesive
    1 x intracameral syringe
    Bacterial fermentation
    0.8
    Sodium Hyaluronate
    1.0
    10
    1 x 27 G cannula
    Lidocaine
    1.0
    10
    2 x topical ampules (see below*)
    Hydrochloride
    VISTHESIA 1.5%
    Viscous-cohesive
    1 x intracameral syringe
    Bacterial fermentation
    0.8
    Sodium Hyaluronate
    1.5
    15
    1 x 27 G cannula
    Lidocaine
    1.0
    10
    2 x topical ampules (see below*)
    Hydrochloride
    *VISTHESIA topical ampule11
    n/a
    2 x topical ampules
    Bacterial fermentation
    2 x 0.3
    Sodium Hyaluronate
    2 x 0.3
    2 x 3
    Lidocaine
    2.0
    20
    Hydrochloride
    VISTHESIA 1.0% intra12
    Viscous-cohesive
    1 x intracameral syringe
    Bacterial fermentation
    0.8
    Sodium Hyaluronate
    1.0
    10
    1 x 27 G cannula
    Lidocaine
    1.0
    10
    Hydrochloride
    VISTHESIA 1.5% intra12
    Viscous-cohesive
    1 x intracameral syringe
    Bacterial fermentation
    0.8
    Sodium Hyaluronate
    1.5
    15
    1 x 27 G cannula
    Lidocaine
    1.0
    10
    Hydrochloride

    All OVDs are phthalate free and have a pH range between 6.8 and 7.6.
    The shelf life for all OVDs is 3 years except for TWINVISC, which has a shelf life of 2 years

  • Classification
    Single pack content
    Multipack content
    Origin
    Volume (ml)
    Substance
    Concentration I (%)
    Concentration II (mg/ml)
    COMBIVISC
    Viscous-cohesive
    1 x intracameral syringe
    5 x intracameral syringes
    Bacterial fermentation
    1.0
    Sodium Hyaluronate
    1.5
    15
    1 x 25 G cannulas
    5 x 25 G cannulas
    Medium-viscosity dispersive
    1 x intracameral syringes
    5 x intracameral syringes
    Bacterial fermentation
    0.85
    Sodium Hyaluronate
    3.0
    30
    1 x 25 G cannula
    5 x 25 G cannulas
    TWINVISC
    Medium-viscosity dispersive
    1 x two-chamber intracameral syringe
    -
    Bacterial fermentation
    0.7
    Sodium Hyaluronate
    2.2
    22
    1 x 25 G cannula
    Viscous-cohesive
    1 x two-chamber intracameral syringe
    -
    Bacterial fermentation
    0.7
    Sodium Hyaluronate
    1.0
    10
    1 x 25 G cannula

    All OVDs are phthalate free and have a pH range between 6.8 and 7.6.
    The shelf life for all OVDs is 3 years except for TWINVISC, which has a shelf life of 2 years

  • Classification
    Single pack content
    Multipack content
    Origin
    Volume (ml)
    Substance
    Concentration I (%)
    Concentration II (mg/ml)
    Z-CELCOAT
    Low-viscosity dispersive
    1 x intracameral syringe
    10 x intracameral syringes
    Botanical
    2.1
    Hydroxypropyl-methylcellulose
    2.0
    20
    1 x 23 G cannula
    10 x 23 G cannulas
    Z-HYALCOAT
    Medium-viscosity dispersive
    1 x intracameral syringe
    10 x intracameral syringes
    Bacterial fermentation
    0.85
    Sodium Hyaluronate
    3.0
    30
    1 x 25 G cannula
    10 x 25 G cannulas

    All OVDs are phthalate free and have a pH range between 6.8 and 7.6.
    The shelf life for all OVDs is 3 years except for TWINVISC, which has a shelf life of 2 years

  • Classification
    Single pack content
    Multipack content
    Origin
    Volume (ml)
    Substance
    Concentration I (%)
    Concentration II (mg/ml)
    Z-HYALIN
    Viscous-cohesive
    1 x intracameral syringe
    10 x intracameral syringes
    Bacterial fermentation
    1.0
    Sodium Hyaluronate
    1.0
    10
    1 x 27 G cannula
    10 x 27 G cannulas
    Z-HYALIN plus
    Viscous-cohesive
    1 x intracameral syringe
    10 x intracameral syringes
    Bacterial fermentation
    1.0
    Sodium Hyaluronate
    1.5
    15
    1 x 27 G cannula

    10 x 27 G cannulas
    Z-HYALON
    Viscous-cohesive

    1 x intracameral syringe

    -
    Rooster comb
    0.55 or 0.85
    Sodium Hyaluronate
    1.0
    10

    1 x 27 G cannula
    Z-HYALON plus
    Super-viscous cohesive
    1 x intracameral syringe

    -
    Rooster comb

    0.55 or 0.85
    Sodium Hyaluronate
    1.4
    14
    1 x 27 G cannula

    All OVDs are phthalate free and have a pH range between 6.8 and 7.6.
    The shelf life for all OVDs is 3 years except for TWINVISC, which has a shelf life of 2 years

Technical information

Molecular weight (megadalton)13
Zero-shear viscosity (Pa s)14
CDI
Pseudo-plasticity
Osmolality (mOsmol/kg)
Storage temperature (°C)
Overall comforter
VISTHESIA 1.0%
2.9
72
39
75
280–330
2–8
VISTHESIA 1.5%
2.9
295
44
133
280–330
2–8
VISTHESIA Topical ampule11
2.9
1
n/a
n/a
270–320
2–8
VISTHESIA 1.0% intra12
2.9
72
39
75
280–330
2–8
VISTHESIA 1.5% intra12
2.9
295
44
133
280–330
2–8
Multitalents
COMBIVISC
Cohesive 2.9
Cohesive 295
Cohesive 44
Cohesive 133
Cohesive 300–360
2–8
Dispersive 1.0
Dispersive 47
Dispersive 39
Dispersive 10
Dispersive 300–360
2–8
TWINVISC
Dispersive 1.0
Dispersive 14
Dispersive 26
Dispersive 8
Dispersive 300–360
2–8
Cohesive 2.1
Cohesive 18
Cohesive 36
Cohesive 18
Cohesive 300–350
2–8
Protecting layers

Z–CELCOAT

0.08

8

–

–

265–300

2–30

Z–HYALCOAT
1.0
47
18
10
300–360
2–8
Space creators

Z–HYALIN
2.9
72
39
75
300–350

2–8
Z–HYALIN plus
2.9
295
44
133
300–360
2–8

Z–HYALON
5.0
1.000

–

–

200–400

2–25
Z–HYALON plus
5.0

3.300

–

–

200–400

2–25

Downloads

    • Preview image of IOL & OVD Portfolio brochure AT TORBI 719M/MP & AT LISA tri toric 949M/MP - digital version EN

      IOL & OVD Portfolio brochure AT TORBI 719M/MP & AT LISA tri toric 949M/MP - digital version EN

      Pages: 7
      File size: 1 MB
      Download
    • Preview image of VISTHESIA / VISTHESIA intra Datasheet EN

      VISTHESIA / VISTHESIA intra Datasheet EN

      Pages: 2
      File size: 154 KB
      Download
    • Preview image of TWINVISC Datasheet EN

      TWINVISC Datasheet EN

      Pages: 2
      File size: 179 KB
      Download
    • Preview image of Z-CELCOAT Datasheet EN

      Z-CELCOAT Datasheet EN

      Pages: 2
      File size: 103 KB
      Download
    • Preview image of Z-HYALCOAT Datasheet EN (non-EU version)

      Z-HYALCOAT Datasheet EN (non-EU version)

      Pages: 2
      File size: 167 KB
      Download
    • Preview image of Z-HYALIN / Z-HYALIN plus Datasheet EN

      Z-HYALIN / Z-HYALIN plus Datasheet EN

      Pages: 2
      File size: 194 KB
      Download
    • Preview image of VISTHESIA Flyer digital version EN

      VISTHESIA Flyer digital version EN

      Pages: 2
      File size: 1 MB
      Download
    • Preview image of COMBIVISC Flyer digital version EN

      COMBIVISC Flyer digital version EN

      Pages: 4
      File size: 314 KB
      Download
    • Preview image of TWINVISC Flyer digital version EN

      TWINVISC Flyer digital version EN

      Pages: 2
      File size: 1 MB
      Download
    • Preview image of Z-HYALIN Flyer digital version EN

      Z-HYALIN Flyer digital version EN

      Pages: 2
      File size: 2 MB
      Download

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Personal contact information

If you want to have more information on data processing at ZEISS please refer to our data privacy notice. 

  • 1

    Except: Z-HYALON, Z-HYALON plus, Z-CELCOAT
  • 2

    VISTHESIA 1.0% and VISTHESIA 1.5% are not for sale in the UK or Portugal
  • 3

    F. Poyales-Galan, G. Pirazzoli: Clinical Evaluation of Endothelial Cell Decrease with VISTHESIA In: Phacoemulsification Surgery. JCRS Vol. 31, Nov. 2005
  • 4

    S. K. Pandey et al.: Evaluation of the cataractgenic effect of viscoanesthetic solutions on the rabbit crystalline lens. JCRS Vol. 31, July 2005
  • 5

    Harry Domack: Z-HYALIN Plus: A Versatile Cohesive Agent. Cataract & Refractive Surgery Today, Europe, July/August 2011
  • 6

    S. A. Arshinoff, M Jafari: New classification of ophthalmic viscosurgical devices. JCRS Vol. 31, Nov. 2005
  • 7

    W. W. Hütz et al.: Comparison of viscoelastic substances used in phacoemulsification. JCRS Vol. 22, Sept. 1996
  • 8

    ZEISS: TWINVISC – Two OVDs, one syringe, a unique concept (User testimonial by S. Arshinoff), 2011
  • 9

    G. U. Auffahrt et al.: Comparison of the performance and safety of 2 ophthalmic viscosurgical devices in cataract surgery. JCRS Vol. 43, Jan. 2017
  • 10

    A. D. Steele, V. Andrews: Methylcellulose for endothelial cell protection. Australian and New Zealand Journal of Ophthalmology Vol. 16, 1988
  • 11

    Not available individually; only available with VISTHESIA 1.0% or 1.5%
  • 12

    VISTHESIA intra version does not contain 2 topical ampules
  • 13

    Megadalton = 1 million Dalton
  • 14

    1Pa s = 1000 mPa s
  • 15

    Only applies to Z-HYALIN and Z-HYALIN plus
  • 16

    Also applies to Z-HYALON