Compêndio

Publicações que apresentam o uso de radioterapia intraoperatória (IORT) para tratamentos oncológicos

O foco são indicações, física médica, radiobiologia, aspectos tecnológicos, qualidade de vida e diretrizes e recomendações
1 dezembro 2025 · 10 MIN. LEITURA
Compilado por ZEISS Medical Technology
RESUMO

Lista de artigos sobre a IORT em tratamentos de radioncologia

Neste compêndio de literatura, a ZEISS apresenta vários artigos clínicos sobre a IORT para várias indicações oncológicas, mas também com foco em aspectos relevantes específicos, como física médica, radiobiologia, aspectos tecnológicos, qualidade de vida, cosmese, diretrizes, recomendações ou avaliações de tecnologias em saúde (ATS) em inglês e alemão. O objetivo é fornecer mais informações e compartilhar conhecimentos.

Cada publicação se baseia na opinião profissional do próprio autor ou nos resultados de seu estudo. Elas não refletem necessariamente a opinião da Carl Zeiss Meditec AG e podem não estar de acordo com a avaliação clínica ou a finalidade prevista dos nossos dispositivos médicos. Por isso, a adequação da aplicação clínica de cada publicação deve ser cuidadosamente avaliada pelo médico responsável.

Indicações oncológicas

  • Ano
    Título
    Link
    Publicação
    Autores

    Novembro de 2025

    Comparing intraoperative radiotherapy (IORT) and hypofractionated stereotactic radiotherapy (HSRT) after brain metastasis surgery: impact on oncological outcome and radionecrosis

    Journal of Neuro-Oncology

    Neu M, Shiban E, Krauss P, Sommer B, Roushan Z, Gutser S, Maurer CJ, Janzen T, Stüben G, Kahl KH

    Setembro de 2025

    Intraoperative radiotherapy for resectable brain metastases: a systematic review and meta-analysis

    Radiotherapy and Oncology

    Dejonckheere CS, Schneider M, Potthoff AL, Hamed M, Scafa D, Zeyen T, Friker LL, Grimmer M, Kugel F, Garbe S, Radbruch A, Vatter H, Giordano FA, Herrlinger U, Gkika E, Sarria GR, Layer JP

    Agosto de 2025

    Intraoperative radiotherapy in brain metastasis surgery allows faster transition to systemic therapy

    Neuro-Oncology Practice

    Krauss P, Wolfert C, Bakos J, Stemmer B, Stueben G, Kahl KH, Shiban E

    Julho de 2025

    Intraoperative radiation therapy for glioblastoma and brain metastases: Program development and initial experience from the Philippines

    Journal of Clinical Neuroscience

    Khu KJO, Pascual JSG, Cañal JPA, Cupino NA, Co HCS, Apor AO, Luz U Hernandez MA, Libit SJB, Posadas JRD, Legaspi GD

    Maio de 2025

    Efficacy and safety of low-dose X-rays based intraoperative radiotherapy for high-grade gliomas: a single-center retrospective study

    Frontiers in Oncology

    Wen Z, Liu J, Bai Y, Zhou M, He J, Xu Y, Yan Y, Li F, Gong S, Li J, Cao P

    Abril de 2025

    Resection with intraoperative radiotherapy vs. adjuvant radiotherapy in the treatment of eloquent brain metastases: an analysis of feasibility and safety

    Neurosurgical Review

    Krauss P, Colosimo M, Wolfert C, Stemmer B, Sommer B, Mielke D, Stueben G, Kahl KH, Shiban E

    Outubro de 2024

    P17.11.B Interim analysis of a phase II trial of intraoperative radiotherapy (IORT) with INTRABEAM after surgical resection of brain metastases (BM) (NCT05084092)

    Neuro-oncologia

    Macià I Garau M, Plans Ahicart G, Lucas Calduch A, García Expósito N, Rosselló Gómez A, Fernández Coello A, Vidal Sarró N, Majós Torró C, Pons Escoda A, Ventura Bujalance M, Martín Vaello R, Saldaña Gutiérrez P

    Agosto de 2024

    Intraoperative radiotherapy after neurosurgical resection of brain metastases as institutional standard treatment- update of the oncological outcome form a single center cohort after 117 procedures

    Journal of Neuro-Oncology

    Kahl KH, Krauss PE, Neu M, Maurer CJ, Schill-Reiner S, Roushan Z, Laukmanis E, Dobner C, Janzen T, Balagiannis N, Sommer B, Stüben G, Shiban E

    Abril de 2024

    Multicentric assessment of safety and efficacy of combinatorial adjuvant brain metastasis treatment by intraoperative radiotherapy and immunotherapy

    International Journal of Radiation Oncology, Biology & Physics

    Layer JP, Shiban E, Brehmer S, Diehl CD, de Castro DG, Hamed M, Dejonckheere CS, Cifarelli DT, Friker LL, Herrlinger U, Hölzel M, Vatter H, Schneider M, Combs SE, Schmeel LC, Cifarelli CP, Giordano FA, Sarria GR, Kahl KH

    Janeiro de 2024

    Intraoperative radiotherapy in recurrent IDH-wildtype glioblastoma with gross total resection: A single-center retrospective study

    Clinical Neurology and Neurosurgery

    Bao H, Ai S, Wang G, Yi L, Lai J, Wang S, Lv Z, Li C, Liu Q, Zhao X, Wu C, Liu C, Mi S, Sun X, Hao C, Liang P

    Outubro de 2023

    Intraoperative or postoperative stereotactic radiotherapy for brain metastases: time to systemic treatment onset and other patient-relevant outcomes

    Journal of Neuro-Oncology

    Dejonckheere CS, Layer JP, Hamed M, Layer K, Glasmacher A, Friker LL, Potthoff A, Zeyen T, Scafa D, Koch D, Garbe S, Holz JA, Kugel F, Grimmer M, Schmeel FC, Gielen GH, Forstbauer H, Vatter H, Herrlinger U, Giordano FA, Schneider M, Schmeel LC, Sarria GR

    Setembro de 2023

    Intracranial intraoperative radiotherapy (IORT): evaluation of electrocorticography and peri-operative seizure risk

    Journal of Neuro-Oncology

    Cifarelli CP, Vargo JA, Sener U, Cifarelli DT, Scoville D, Dabir A

    Julho de 2023

    Opportunities and Alternatives of Modern Radiation Oncology and Surgery for the Management of Resectable Brain Metastases

    Cancers

    Diehl CD, Giordano FA, Grosu AL, Ille S, Kahl KH, Onken J, Rieken S, Sarria GR, Shiban E, Wagner A, Beck J, Brehmer S, Ganslandt O, Hamed M, Meyer B, Münter M, Raabe A, Rohde V, Schaller K, Schilling D, Schneider M, Sperk E, Thomé C, Vajkoczy P, Vatter H, Combs SE

    Julho de 2023

    Outcome assessment of intraoperative radiotherapy for brain metastases: results of a prospective observational study with comparative matched-pair analysis

    Journal of Neuro-Oncology

    Layer JP, Hamed M, Potthoff AL, Dejonckheere CS, Layer K, Sarria GR, Scafa D, Koch D, Köksal M, Kugel F, Grimmer M, Holz JA, Zeyen T, Friker LL, Borger V, Schmeel FC, Weller J, Hölzel M, Schäfer N, Garbe S, Forstbauer H, Giordano FA, Herrlinger U, Vatter H, Schneider M, Schmeel LC

    Fevereiro de 2023

    Intraoperative radiotherapy for brain metastases: first-stage results of a single-arm, open-label, phase 2 trial

    National Library of Medicine

    De Castro DG, Sanematsu Jr PI, Pellizzon ACA, Suzuki SH, Fogaroli RC, Dias Jr JES, Gondim GRM, Estrada DA, Silva MLG, Rassi MS, Chen MJ, Giacomelli R, Ramos H, Neto ES, Abrahão CH, Coelho TM, Yu LS, Tannous CQ, Calsavara VF, Giordano FA, Oliveira JG

    Dezembro de 2022

    Resection of supratentorial brain metastases with intraoperative radiotherapy. Is it safe? Analysis and experiences of a single center cohort

    Frontiers in Oncology

    Krauss P, Steininger K, Motov S, Sommer B, Bonk MN, Cortes A, Wolfert C, Stueben G, Shiban E, Henning K

    Dezembro de 2022

    Low-Energy X-Ray Intraoperative Radiation Therapy (Lex-IORT) for Resected Brain Metastases: A Single-Institution Experience

    National Library of Medicine

    Diehl CD, Pigorsch SU, Gempt J, Krieg SM, Reitz S, Waltenberger M, Barz M, Meyer HS, Wagner A, Wilkens J, Wiestler B, Zimmer C, Meyer B, Combs SE

    Julho de 2022

    Intraoperative radiotherapy during awake craniotomies: preliminary results of a single-center case series

    Neurosurgical Review

    Steininger K, Kahl KH, Konietzko I, Wolfert C, Motov S, Krauß PE, Bröcheler T, Hadrawa M, Sommer B, Stüben G, Shiban E

    Março de 2022

    Benchmarking Safety Indicators of Surgical Treatment of Brain Metastases Combined with Intraoperative Radiotherapy: Results of Prospective Observational Study with Comparative Matched-Pair Analysis

    Cancers (Basel)

    Hamed M, Potthoff AL, Layer JP, Koch D, Borger V, Heimann M, Scafa D, Sarria GR, Holz JA, Schmeel FC, Radbruch A, Güresir E,
    Schäfer N, Schuss P, Garbe S, Giordano FA, Herrlinger U, Vatter H, Schmeel LC, Schneider M

    Novembro 2021
    Intraoperative Radiotherapy in Brain Malignancies: Indications and Outcomes in Primary and Metastatic Brain Tumors

    Frontiers in Oncology

    Cifarelli CP, Jacobson GM
    Outubro de 2021
    Dosimetric Comparison of Upfront Boosting With Stereotactic Radiosurgery Versus Intraoperative Radiotherapy for Glioblastoma

    Frontiers in Oncology

    Sarria GR, Smalec Z, Muedder T, Holz JA, Scafa D, Koch D, Garbe S, Schneider M, Hamed M, Vatter H, Herrlinger U, Giordano FA, Schmeel LC
    Agosto de 2021
    Intraoperative radiotherapy with low-energy x-rays after neurosurgical resection of brain metastases- an Augsburg University Medical Center experience
    Strahlentherapie und Onkologie
    Kahl KH, Balagiannis N, Höck M, Schill S, Roushan Z, Shiban E, Müller H, Grossert U, Konietzko I, Sommer B, Maurer CJ, Berlis A, Heidecke V, Janzen T, Stüben G
    Março de 2021
    Dose homogeneity analysis of adjuvant radiation treatment in surgically resected brain metastases: Comparison of IORT, SRS and IMRT indices
    Brachytherapy
    Dahshan BA, Weir JS, Bice RP, Renz P, Cifarelli DT, Poplawski L, Hack J, Vargo JA, Cifarelli CP
    Fevereiro de 2020
    Current approaches to the management of brain metastases
    Clinical Oncology
    Suh JH, Kotecha R, Chao ST, Ahluwalia MS, Sahgal A, Chang EL
    Outubro de 2019
    Intraoperative radiotherapy (IORT) for surgically resected brain metastases: outcome analysis of an international cooperative study
    Journal of Neuro-Oncology
    Cifarelli CP, Brehmer S, Vargo JA, Hack JD, Kahl KH, Sarria-Vargas G, Giordano FA
    Setembro de 2019
    Intraoperative Radiotherapy for Glioblastoma: An International Pooled Analysis
    International Journal of Radiation Oncology, Biology & Physics

    Sarria GR, Sperk E, Xiaodi H, Sarria G, Wenz F, Brehmer S, Fu B, Min S, Zhang H, Qin S, Qiu X, Abo-Madyan Y, Hänggi D, Martinez DA, Cabrera C, Giordano FA

    Maio de 2019
    Intraoperative radiotherapy (IORT) for surgically resected brain metastases: Local control and dosimetric analysis.
    Journal of Global Oncology
    Cifarelli CP, Vargo JA, Hack JD, Renz PB, Poplawski L, Jacobson GM, Kahl KH, Brehmer S, Sarria G, Giordano FA
    Janeiro de 2019
    Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Treatment of Adults With Metastatic Brain Tumors: Executive Summary
    Neurocirurgia
    Olson JJ, Kalkanis SN, Ryken TC
    Agosto de 2018
    Feasibility of dose escalation using intraoperative radiotherapy following resection of large brain metastases compared to post-operative stereotactic radiosurgery
    Journal of Neuro-Oncology
    Vargo JA, Sparks KM, Singh R, Jacobson GM, Hack JD, Cifarelli CP
    Abril de 2018
    Combined stereotactic biopsy and stepping-source interstitial irradiation of glioblastoma multiforme
    Journal of Neurosurgical Sciences
    Brehmer S, Guthier CV, Clausen S, Schneider F, Schulte DM, Benker M, Bludau F, Glatting G, Marx A, Schmiedek P, Hesser J, Wenz F, Giordano FA
    Março de 2018
    Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma (INTRAGO): An Open-Label, Dose-Escalation Phase I/II Trial
    Neurocirurgia
    Giordano FA, Brehmer S, Mürle B, Welzel G, Sperk E, Keller A, Abo-Madyan Y, Scherzinger E, Clausen S, Schneider F, Herskind C, Glas M, Seiz-Rosenhagen M, Groden C, Hänggi D, Schmiedek P, Emami B, Souhami L, Petrecca K, Wenz F
    Outubro de 2016
    Initial Results of a Phase 1/2 Trial on Intraoperative Radiation Therapy (IORT) in Newly Diagnosed Glioblastoma Multiforme (INTRAGO)
    International Journal of Radiation Oncology, Biology & Physics
    Giordano FA, Brehmer S, Muerle B, Welzel G, Sperk E, Schneider F, Clausen S, Schmiedek P, Groden C, Hänggi D, Abo-Madyan Y, Wenz F
    Janeiro de 2016
    Rationale for intraoperative radiotherapy in glioblastoma
    Journal of Neurosurgical Sciences
    Giordano FA, Wenz F, Petrecca K
    Abril de 2015
    Intraoperative radiotherapy to treat newly diagnosed solitary brain metastasis: initial experience and long-term outcomes
    Journal of Neurosurgery
    Weil RJ, Mavinkurve GG, Chao ST, Vogelbaum MA, Suh JH, Kolar M, Toms SA
    Setembro de 2014
    INTRAOPERATIVE RADIOTHERAPY WITH INTRABEAM IN PRIMARY BRAIN TUMORS AFTER RESECTION: PRELIMINARY REPORTS OF 26 CASES
    Neuro-oncologia
    Han X, Fu B, Wu M, Zhang H, Li D, Zhang J, Sun D, Sun S
    Fevereiro de 2014
    Intraoperative radiotherapy (IORT)—a resurrected option for treating glioblastoma?
    Translational Cancer Research
    Giordano FA, Abo-Madyan Y, Brehmer S, Herskind C, Sperk E, Schneider F, Clausen S, Welzel G, Schmiedek P, Wenz F
    Abril de 2006
    Phase I study of intraoperative radiotherapy with photon radiosurgery system in children with recurrent brain tumors: Preliminary report of first dose level (10 Gy)
    International Journal of Radiation Oncology, Biology & Physics
    Kalapurakal JA, Goldman S, Stellpflug W, Curran J, Sathiaseelan V, Marymont MH, Tomita T 
  • Ano
    Título
    Link
    Publicação
    Autores

    Abril de 2024

    Intraoperative radiotherapy combined with spinal stabilization surgery-a novel treatment strategy for spinal metastases based on a first single-center experiences

    Journal of Neuro-Oncology

    Krauss P, Wolfert CL, Sommer B, Stemmer B, Stueben G, Kahl KH, Shiban E

    Agosto de 2021

    First Experience of Intra-Operative Radiation Therapy (IORT) during Kyphoplasty in Patients Diagnosed with Spinal Metastasis in Iran

    Austin Journal of Clinical Case Reports 

    Seddighi AS, Nikouei A, Seddighi A, Akbari ME, Arjmand Y, Ommi D, Zali A, Hosseini M

    Novembro de 2020

    Long-term outcome after combined kyphoplasty and intraoperative radiotherapy (Kypho-IORT) for vertebral tumors

    BioMed Central

    Bludau F, Winter L, Welzel G, Obtertacke U, Schneider F, Wenz F, Ruder AM, Giordano FA

    Maio de 2019
    Combined kyphoplasty and intraoperative radiotherapy (Kypho-IORT) versus external beam radiotherapy (EBRT) for painful vertebral metastases - a randomized phase III study
    BMC Cancer
    Bludau F, Welzel G, Reis T, Abo-Madyan Y, Sperk E, Schneider F, Clausen S, Ruder AM, Obertacke U, Ghaly MM, Wenz F, Giordano FA
    Maio de 2018
    Phase I/II trial of combined kyphoplasty and intraoperative radiotherapy in spinal metastases
    The Spine Journal
    Bludau F, Welzel G, Reis T, Schneider F, Sperk E, Neumaier C, Ehmann M, Clausen S, Obertacke U, Wenz F, Giordano FA
    Agosto de 2017
    Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases
    Scientific Reports
    Mohme M, Riethdorf S, Dreimann M, Werner S, Maire CL, Joosse SA, Bludau F, Mueller V, Neves RPL, Stoecklein NH, Lamszus K, Westphal M, Pantel K, Wikman H, Eicker SO
    Setembro de 2015
    Kyphoplastie kombiniert mit intraoperativer Radiotherapie (Kypho-IORT)
    Der Radiologe
    Bludau F, Reis T, Schneider F, Clausen S, Wenz F, Obertacke U
    Janeiro de 2014
    Kypho-IORT: the first French treatment
    Translational Cancer Research
    Miglierini P, Dam-Hieu P, Key S
    Julho de 2013
    Kyphoplastie in Kombination mit intraoperativer Radiotherapie
    Der Orthopäde
    Kayser R, Ender SA, Asse E, Wilhelm E, Adler F, Schmidt R, Wenz F, Obertacke U, Bludau F

    Janeiro de 2012

    Kyphoplasty and intra-operative radiotherapy, combination of kyphoplasty and intra-operative radiation for spinal metastases: technical feasibility of a novel approach

    International Orthopaedics
    Schmidt R, Wenz F, Reis T, Janik K, Bludau F, Obertacke U
  • Ano
    Título
    Link
    Publicação
    Autores

    Dezembro de 2025

    Intraoperative radiotherapy in elderly patients with breast cancer: long-term follow-up results of the prospective phase II trial TARGIT-E

    BMC Cancer

    Sperk E, Lemanski C, Neumaier C, Lauer J, Siefert V, Völker R, Lindner C, Niehoff P, Tallet AR, Racadot S, Petit A, Pazos M, Le-Blanc Onfroy M, Martin E, Reuter C, Hermann RM, Pohl F, Friedrichs K, Würschmidt F, Pigorsch S, Kolberg HC, Graf H, Brunner TB, Malter W, Park-Simon TW, Brucker C, Fleckenstein J, Petersen C, Tuschy B, Wilken EE, Büttner S, Sütterlin M, Flyger H, Wenz F

    Novembro de 2025

    Intra-Operative Radiotherapy with Photons - Update of a Single Institution Registry Trial

    Clinical Breast Cancer

    Oska C, Kohilakis E, Feldman S, Tome W, Jin Y, Kim R, Mehta K, McEvoy M, Fox J

    Julho de 2025

    Optimizing intraoperative radiotherapy as a tumor bed boost with whole-breast irradiation in breast cancer

    World Journal of Surgical Oncology

    Chen J, Zhou X, Weng KG, Lei QQ, Ying M, Wu YZ, Wang Y, Zeng XH, Long YY

    Junho de 2025

    IORT for early-stage, low-risk breast cancer: outcomes from a prospective, observational study

    Clinical and Translational Radiation Oncology

    Palacios-Eito A, del Carmen Moreno-Manzanaro Moreno M, Espinosa-Calvo M, Ginés-Santiago F, Camús-Martínez JA, Calvo-Tudela A, Rioja-Torres P, Romero-Martín S, Miñano-Herrero JA, Sarria GR, García-Cabezas S

    2025

    Long-term oncologic outcome of intraoperative radiotherapy (IORT) with low-energy X-rays as a tumor-bed boost in Korean patients with breast cancer

    Cancer Treat Res Commun

    Baek SH, Bae SJ, Kook Y, Cho Y, Ahn SG, Kim JW, Lee IJ, Jeong J

    Maio de 2025

    Oncological outcomes of breast cancer patients after planned IORT boost with low-kV x-rays-results of the TARGIT BQR prospective phase IV trial

    Strahlentherapie und Onkologie

    Goerdt L, Pömsl J, Kraus-Tiefenbacher U, Brück V, Kaiser C, Keymer R, Abo-Madyan Y, Fleckenstein K, Berlit S, Tuschy B, Sütterlin M, Wenz F, Sperk E

    Maio de 2025

    Long-term results of a prospective multicenter trial of APBI with photon IORT

    Cancers

    García-Cabrera L, Pinar-Sedeño B, Cabezón-Pons MA, Rodriguez-Ibarria N, Dominguez-Dominguez A, Aguiar-Santana D, Martín-Barrientos P, Rey-López I, Lara PC, Lloret-Saez-Bravo M

    Dezembro de 2024

    Five-year results of a prospective trial of IORT-photon boost and hypofractionated whole-breast irradiation after breast-conserving surgery

    Clinical and Translational Oncology

    Burgos-Burgos J, Vega V, Macias-Verde D, Vicente E, Murias C, Santana C, Téllez R, Lara PC

    Novembro de 2024

    Outcomes from real-world data on intraoperative electronic radiotherapy for the treatment of early-stage breast cancer: long-term recurrence and survival outcomes from a single center.

    International Journal of Breast Cancer

    De la Mata D, Santiago-Concha BG, Bargalló-Rocha JE, Robles-Vidal CD, Gómez-Pue D, Castorena-Rojí G, Hinojosa-Gómez J, Flores-Vázquez F, Blake-Cerda M, Enriquez-Barrera M, Maffuz-Aziz A

    Outubro de 2024

    Real world clinical outcomes from targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy for breast cancer: data from a large cohort at a national cancer institute

    Frontiers in Oncology

    Vinante L, Vaidya JS, Caroli A, Mileto M, Piccoli E, Avanzo M, Barresi L, Marson M, Montico M, Baboci L, Perin T, Urbani M, Puglisi F, Mascarin M, Massarut S

    Outubro de 2024

    IORT-photon boost plus hypofractionated whole breast irradiation in patients with breast cancer after primary systemic treatment: feasibility, safety and clinical results

    Clinical and Translational Oncology

    Burgos-Burgos J, Vega V, Macias-Verde D, Vicente E, Murias C, Santana C, Lara PC

    Setembro de 2024

    A systematic review on the techniques, long-term outcomes, and complications of partial breast irradiation after breast-conserving surgery for early-stage breast cancer

    Scientific Reports

    Ning J, Cheng G, Wu N

    Setembro de 2024

    Case report: IORT as an alternative treatment option for breast cancer patients with difficulty staying still

    Frontiers in Oncology

    Bhimani F, McEvoy M, Chen Y, Gupta A, Pastoriza J, Fruchter S, Bitan ZC, Tomé WA, Mehta K, Fox J, Feldman S

    Agosto de 2024

    Intraoperative radiotherapy: An alternative to whole-breast external beam radiotherapy in the management of highly selective breast cancer: A SEER database analysis

    Cancer Medicine

    Sun D, Lu G, Liang F, Zhang W, Zeng T, Ling Y, Peng H, Xia T, Hu M, Chen X

    Maio de 2024

    Acute and Long-Term Toxicity after Planned Intraoperative Boost and Whole Breast Irradiation in High-Risk Patients with Breast Cancer—Results from the Targeted Intraoperative Radiotherapy Boost Quality Registry (TARGIT BQR)

    Cancers

    Goerdt L, Schnaubelt R, Kraus-Tiefenbacher U, Brück V, Bauer L, Dinges S, von der Assen A, Meye H, Kaiser C, Weiss C, Clausen S, Schneider F, Abo-Madyan Y, Fleckenstein K, Berlit S, Tuschy B, Sütterlin M, Wenz F, Sperk E

    Abril de 2024

    Intraoperative radiotherapy (IORT) of early breast cancer with low-energy x-rays in breast-conserving surgery: Prospective identification of pre- and intraoperative factors influencing the feasibility of IORT

    Strahlenther Onkol

    Grimm A, Wollmann E, Sperk E, Weiß C, Sütterlin M, Berlit S, Tuschy B

    Março de 2024

    Combined Ultrahypofractionated Whole-Breast Irradiation and IORT-Boost: A Safety and Feasibility Analysis

    Cancers (Basel)

    Burgos-Burgos J, Vega V, Macias-Verde D, Gómez V, Vicente E, Murias C, Santana C, Lara PC

    Outubro de 2023

    Case Report: Bilateral targeted intraoperative radiotherapy: a safe and effective alternative for synchronous bilateral breast cancer

    Frontiers in Oncology

    Bhimani F, McEvoy M, Gupta A, Pastoriza J, Shihabi A, Basavatia A, Tomé WA, Fox J, Mehta K, Feldman S.

    Julho de 2023

    Experience with intraoperative radiation therapy in an urban cancer center

    Radioterapia

    Andraos TY, Skalina KA, Feldman S, Mehta K, Tome WA, McEvoy MP, Gupta AM, Fox JL

    Maio de 2023

    Case Report: Intraoperative radiotherapy as the new standard of care for breast cancer patients with disabling health conditions or impairments

    Frontiers in Oncology

    Omosule M, De Silva-Minor S, Coombs N

    Janeiro de 2023

    Comparison of clinical outcomes between low- and high-risk groups of early breast cancer patients treated with intraoperative radiotherapy in addition to external beam radiation: a multi-centre prospective study

    World Journal of Surgery

    Mosiun JA, See MH, Teoh LY, Danaee M, Lai LL, Ng CH, Yip CH, Teh MS, Taib NAM, Bustam A, Malik RA, Saad M, Jamaris S, Ung NM

    Fevereiro de 2023

    Breast Conserving Surgery in Combination With Targeted Intraoperative Radiotherapy Compared to Mastectomy for In-breast-tumor-recurrence

    National Library of Medicine

    Kolberg HC, Niesing H, Vaidya JS, Akpolat-Basci L, Maguz A, Hoffmann O, Loevey G, Stephanou M, Kolberg-Liedtke C

    Dezembro de 2022

    A single-institution retrospective analysis of intraoperative radiation boost during breast-conservation treatment for breast cancer

    Journal of Cancer Research and Clinical Oncology

    Hochhertz F, Hass P, Röllich B, Ochel HJ, Gawish A

    Setembro de 2022

    The case for risk-stratified IORT for early breast cancer

    BRACHYTHERAPY An International Multidisciplinary Journal

    Refaat T, Gros SE, Small Jr W

    Setembro de 2022

    Intraoperative radiation therapy for early-stage breast cancer: a single-institution experience

    National Library of Medicine

    Giap F, O'stehen L, Liu I, Spiguel LE, Shaw CM, Morris CG, Vega RBM, Lightsey J, Bradley JA, Mendenhall NP, Okuniedd P, Lockney NA

    Agosto de 2022

    Global adoption of single-shot targeted intraoperative radiotherapy (TARGIT-IORT) for breast cancer—better for patients, better for healthcare systems

    Frontiers in Oncology

    Vaidya JS, Vaidya UJ, Baum M, Bulsara MK, Joseph D, Tobias JS

    Agosto de 2022

    Prognosis comparison between intraoperative radiotherapy and whole-breast external beam radiotherapy for T1–2 stage breast cancer without lymph node metastasis treated with breast-conserving surgery: A case–control study after propensity score matching

    Frontiers in Oncology

    Chen Q, Qu L, He Y, Xu J, Deng Y, Zhou Q, Yi W

    Julho de 2022

    Risk-Stratified Intraoperative Radiation Therapy as a Definitive Adjuvant Radiation Therapy Modality for Women With Early Breast Cancer

    Scientific Reports

    Small Jr W, Refaat T, Feldman SM, Holmes D

    Julho de 2022

    Accelerated Partial Breast Irradiation with Intraoperative Radiotherapy Is Effective in Luminal Breast Cancer Patients Aged 60 Years and Older

    Journal of Personalized Medicine

    Falco M, Masojć B, Rolla M, Czekała A, Milchert-Leszczyńska M, Pietruszewska J

    Julho de 2022

    Case Report: Can Targeted Intraoperative Radiotherapy in Patients With Breast Cancer and Pacemakers be the New Standard of Care?

    Frontiers in Oncology

    Bhimani F, Johnson K, Brodin NP, Tomé WA, Fox J, Mehta K, McEvoy M, Feldman S

    Junho de 2022

    Breast preservation after local recurrence of breast cancer: Comparison of length and quality of life (QoL) between breast conserving surgery with intraoperative radiotherapy (TARGIT-IORT) versus mastectomy.

    Journal of Clinical Oncology

    Kolberg HC, Niesing H, Vaidya JS, Akpolat-Basci L, Maguz A, Hoffmann O, Loevey G

    Junho de 2022

    Targeted Intraoperative Radiotherapy (TARGIT-IORT) for Early-Stage Invasive Breast Cancer: A Single Institution Experience

    Frontiers in Oncology

    Brown A, Buss EJ, Chin C, Liu G, Lee S, Rao R, Taback B, Wiechmann L, Horowitz D, Choi JC, Katz LM, Connolly EP

    Março de 2022

    Long-Term Outcomes of an International Cooperative Study of Intraoperative Radiotherapy Upfront Boost With Low Energy X-Rays in Breast Cancer

    National Library of Medicine

    Sarria GR, Ramos ML, Palacios A, Del Castillo R, Castro R, Calvo A, Cotrina JM, Heredia A, Galarreta JA, Fuentes-Rivera P, Avalos A, Martinez DA, Colqui K, Ziegler G, Schmeel LC, Pinillos LV, Wenz F, Giordano FA, Sarria GJ, Sperk E

    Março de 2022

    Effectiveness and safety of intraoperative radiotherapy (IORT) with low-energy X-rays (INTRABEAM®) for accelerated partial breast irradiation (APBI)

    Clinical and Translational Oncology

    Laplana M, García‑Marqueta M, Sánchez‑Fernández JJ, Martínez‑Pérez E, Pérez‑Montero H, Martínez‑Montesinos I, Eraso A, Saldaña P, Martín R, Martín MI, Pla MJ, García‑Tejedor A, Guedea F

    Fevereiro de 2022

    Impact of targeted intraoperative (TARGIT-IORT) tumor bed boost during breast conserving surgery for early breast cancer on breast cancer associated and non-breast cancer associated mortality and morbidity

    American Association for Cancer Research

    Kolberg HC, Gutberlet S, Vaidya JS, Krajewska M, Lövey G, Hoffmann O, Stephanou M, Kolberg-Liedtke C

    Janeiro de 2022

    Intraoperative radiation therapy for early stage breast cancer

    BMC Surgery

    Zangouri V, Nasrollahi H, Taheri A, Akrami M, Arasteh P, Hamedi SH, Johari MG, Karimaghaee N, Ranjbar A, Karami MY, Tahmasebi S, Mosalaei A, Talei A

    Janeiro de 2022

    Intraoperative Radiotherapy for Breast Cancer in Elderly Women 

    Clinical Breast Cancer 

    Guillerm SO, Bourstyn E, Itti R, Cahen-Doidy L, Quéro L, Labidi M, Marchand E, Lorphelin H, Giacchetti S, Cuvier C, Espié M, Teixeira L, Hennequin C

    Novembro 2021

    Single institute experience of intraoperative radiation therapy in early-stage breast cancer

    Medicine (Baltimore)

    Chi MS, Ko HL, Chen CC, Hsu CH, Chen LK, Cheng FT

    Novembro 2021

    Intraoperative irradiation in breast cancer: preliminary results in 80 patients as partial breast irradiation or anticipated boost prior to hypo-fractionated whole breast irradiation

    Clinical and Translational Oncology

    Li X, Sanz J, Argudo N, Vernet‑Tomas M, Rodríguez N, Torrent L, Fernández‑Velilla E, Pera O, Huang Y, Nicolau P, Jiménez M, Segura M, Algara M

    Novembro 2021

    Surgical and Oncologic Outcomes With Intraoperative Radiation Therapy for Early Breast Cancer

    The American Surgeon

    Friedman-Eldar O , Layton C, De Castro Silva I, Moller MG, Allen A, Franceschi D, Isrow D, Samuels S, Takita C, Avisar E

    Julho de 2021

    TARGIT-IORT during lumpectomy for breast cancer- better for patients than other PBI approaches 

    International Journal of Radiation Oncology, Biology & Physics

    Vaidya JS, Bulsara M, Sperk E, Massarut S, Douek M, Alvarado M, Pigorsch S, Holmes D, Bernstein M, Saunders C, Flyger H, Joseph D, Wenz F, Tobias JS, investigadores do TARGIT-A

    Junho de 2021

    Hypofractionated whole breast irradiation after IORT treatment is safe in patients receiving adjuvant chemotherapy

    Clinical and Translational Oncology

    Burgos-Burgos J, Vega V, Macias-Verde D, Gómez V, Travieso-Aja M, Travieso J, Vicente E, Murias C, Santana C, Ospina J, Lara PC 

    Maio de 2021

    New clinical and biological insights from the international TARGIT-A randomised trial of targeted intraoperative radiotherapy during lumpectomy for breast cancer

    British Journal of Cancer

    Vaidya JS, Bulsara M, Baum M, Wenz F, Massarut S, Pigorsch S, Alvarado M, Douek M, Saunders C, Flyger HL, Eiermann W, Brew-Graves C, Williams NR, Potyka I, Roberts N, Bernstein M, Brown D, Sperk E, Laws S, Sütterlin M, Corica T, Lundgren S, Holmes DR, Vinante L, Bozza F, Pazos M, Le Blanc-Onfroy M, Gruber G, Polkowski W, Dedes KJ, Niewald M, Blohmer J, McCready D, Hoefer R, Kelemen P, Petralia G, Falzon M, Joseph DJ, Tobias JS

    Abril de 2021

    Intraoperative radiotherapy booster as part of breast-conservation therpy for breast cancer: a single-institution retrospective analysis 

    Strahlentherapie und Onkologie

    Stoian R, Erbes T, Zamboglou C, Scholber J, Galney M, Sachpazidis I, Haehl E, Spohn SK, Verma V, Krug D, Rühle A, Juhasz-Böss I, Grosu AL, Nicolay NH, Sprave T 

    Abril de 2021

    Comparison of IORT (Radical and Boost Dose) and EBRT in Terms of Disease-Free Survival and Overall Survival according Demographic, Pathologic, and Biological Factors in Patients with Breast Cancer 

    International Journal of Oncology 

    Hashemi S, Javadi S, Akbari ME, Mirzaei H, Mahdavi SR

    Março de 2021

    Patients Older 65 Years With Early Breast Cancer Prefer Intraoperative Radiation as a Locoregional Treatment Choice

    Annals of Surgical Oncology

    Tang A, Cohan CM, Beattie G, Cureton EL, Svahn JD, Lyon LL, Kelly JF, Shim VC

    Fevereiro de 2021 

    Assessment of Thyroid Lobe Dose in Breast Cancer Intraoperative Radiotherapy 

    Journal of Biomedical Physics and Engineering 

    Farkhani RR, Gholamhosseinian H, Anvari K, Forghani MN

    Fevereiro de 2021

    Preoperative selection of patients with early-stage invasive breast cancer for intraoperative radiation therapy (IORT): A single-institution experience

    Cancer Research

    Brown AM, Chin C, Connolly E, Rao R, Taback B, Wiechmann L

    Fevereiro de 2021 

    Intraoperative radiotherapy in early breast cancer: observational comparison with whole breast radiotherapy 

    Cirugía Espanola 

    Guillén JRO, Almudi EH, Osorio GM, Carreras RI, Gómez JAF, Gómez IV, Mur CG, Franco MCC 

    Fevereiro de 2021

    Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment

    British Journal of Cancer

    Vaidya JS, Bulsara M, Baum M, Tobias JS on behalf of TARGIT-A trial authors

    Janeiro de 2021

    TARGIT-R (Retrospective): 5-Year Follow-Up Evaluation of Intraoperative Radiation Therapy (IORT) for Breast Cancer Performed in North America

    Annals of Surgical Oncology

    Valente SA, Tendulkar RD, Cherian S, Shah C, Ross DL, Lottich SC, Laronga C, Broman KK, Donnelly ED, Bethke KP, Shaw C, Lockney NA, Pederson A, Rudolph R, Hasselle M, Kelemen P, Hermanto U, Ashikari A, Kang S, Hoefer RA, McCready D, Fyles A, Escallon J, Rohatgi N, Graves J, Graves G, Willey SC, Tousimis E, Riley L, Deb N, Tu C, Small Jr. W, Grobmyer SR

    Janeiro de 2021

    Intraoperative radiotherapy for breast cancer: powerful evidence to change practice

    Clinical Oncology 

    Vaidya JS, Bulsara M, Baum M, Alvarado M, Bernstein M, Massarut S, Saunders C, Sperk E, Wenz F, Tobias JS, investigadores do TARGIT-A 

    Outubro de 2020

    Results of intraoperative radiotherapy given as a boost after breast conserving-surgery

    Gland Surgery

    Onthong K, Chakkabat C, Nantavithya C, Shotelersuk K, Denariyakoon S, Vongsaisuwon M, Chulakadabbav A, Chatamra K, Saksornchai K

    Agosto de 2020

    Cardiac serum marker alterations after intraoperative radiotherapy with low-energy x-rays in early breast cancer as an indicator of possible cardiac toxicity

    Strahlentherapie und Onkologie

    Stefanovic S, Berlit S, Sperk E, Wenz F, Weiß C, Trinkmann F, Sütterlin M, Tuschy B

    Agosto de 2020

    Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial

    The BMJ

    Vaidya JS, Bulsara M, Baum M, Wenz F, Massarut S, Pigorsch S, Alvarado M, Douek M, Saunders C, Flyger HL, Eiermann W, Brew-Graves C, Williams NR, Potyka I, Roberts N, Bernstein M, Brown D, Sperk E, Laws S, Sütterlin M, Corica T, Lundgren S, Holmes DR, Vinante L, Bozza F, Pazos M, Le Blanc-Onfroy M, Gruber G, Polkowski W, Dedes KJ, Niewald M, Blohmer J, McCready D, Hoefer R, Kelemen P, Petralia G, Falzon M, Joseph DJ, Tobias JS, TARGIT-A trial authors

    Junho de 2020

    Breast-conserving surgery with intraoperative radiotherapy in recurrent breast cancer: the patient’s perspective

    Breast Cancer Research and Treatment

    Elfgen C, Gürth U, Gruber G, Birrer S, Bjelic-Radisic V, Fleisch M, Tausch CJ 

    Abril de 2020

    Effect of Delayed Targeted Intraoperative Radiotherapy vs Whole-Breast Radiotherapy on Local Recurrence and Survival Long-term Results From the TARGIT-A Randomized Clinical Trial in Early Breast Cancer

    JAMA Oncology

    Vaidya JS, Bulsara M, Saunders C, Flyger H, Tobias JS, Corica T, Massarut S, Wenz F, Pigorsch S, Alvarado M, Douek M, Eiermann W, Brew-Graves C, Williams N, Potyka I, Roberts N, Bernstein M, Brown D, Sperk E, Laws S, Sütterlin M, Lundgren S, Holmes D, Vinante L, Bozza F, Pazos M, Le Blanc-Onfroy M, Gruber G, Polkowski W, Dedes KJ, Niewald M, Blohmer J, McCready D, Hoefer R, Kelemen P, Petralia G, Falzon M, Baum M, Joseph D

    Março de 2020

    The actual benefit of intraoperative radiation therapy using 50 kV x-rays in early breast cancer: A retrospective study of 676 patients

    The Breast Journal

    Tallet A, Racadot S, Boher J.-M, Cohen M, Barrou J, Houvenaeghel G, Gutowski M, Delmond L, Lemanski C

    Janeiro de 2020

    Intraoperative partial irradiation for highly selected patients with breast cancer: Results of the INTRAOBS prospective study

    Cancer/Radiothérapie

    Lemanski C, Bourgier C, Draghici R, Thezenas S, Morel A, Rouanet P, Colomboe PE, Mourregot A, Delmond L, Fenoglietto P, Ailleres N, Azriaa D, Gutowski M

    Dezembro de 2019

    Intraoperative radiation therapy for breast cancer—Immediate and 30-month oncological outcomes

    The Breast Journal

    Melnik I, Yerushalmi R, Sobol Y, Magen A, Givon-Madhala O, Birinbaum Y, Fenig E, Sharon E

    Outubro de 2019

    Outcomes of selective whole breast irradiation following lumpectomy with intraoperative radiation therapy for hormone receptor positive breast cancer

    American Journal of Surgeons

    Broman K, Sun W, Zhou JM, Fridley B, Diaz R, Laronga C

    Setembro de 2019

    First per Protocol Analysis of the Prospective Phase II Study of Intraoperative Radiotherapy (IORT) in Elderly Patients with Small Breast Cancer: Targit E(lderly)

    International Journal of Radiation Oncology, Biology & Physics

    Sperk E

    Julho de 2019

    Targeted Intraoperative Radiotherapy During Breast-conserving Surgery for Breast Cancer in Patients After Implant Augmentation

    International Institute of Anticancer Research

    Kolberg HC, Uhl V, Massarut S, Holmes D, Kolberg-Liedtke C, Kelly EW, Lövey G, Vaidya JS

    Janeiro de 2019

    Patient preferences for adjuvant radiotherapy in early breast cancer are strongly influenced by treatment received through random assignment

    European Journal of Cancer Care

    Corica T, Saunders CM, Bulsara MK, Taylor M, Joseph DJ, Nowak AK 

    Dezembro de 2018

    A Prospective Analysis of Quality of Life and Toxicity Outcomes in Treating Early Breast Cancer With Breast Conservation Therapy and Intraoperative Radiation Therapy

    Frontiers in Oncology

    Sosin M, Gupta SS, Wang JS, Costellic CD, Gulla A, Bartholomew AJ, O'Neill SC, Hechenbleikner EM, Collins BT, Rudra S, Collins SP, Chaldekas KM, Seevaratnam S, Langan RC, Willey SC, Tousimis EA

    Dezembro de 2018

    Breast conserving surgery with targeted intraoperative radiotherapy for the management of ductal carcinoma in situ

    Journal of Surgical Oncology

    Banks A, Coronado G, Zimmerman R, Iyengar G, Holmes DR

    Novembro de 2018

    A Single-Institution Experience in the Preoperative Selection of DCIS Patients for IORT using the ASTRO Consensus Guidelines

    Advance Radiation Oncology

    Chin C, Hirji S, Onishi M, Ha R, Taback B, Horowitz DP, Connolly EP

    Novembro de 2018

    A phase II study investigating the acute toxicity of targeted intraoperative radiotherapy as tumor-bed boost plus whole breast irradiation after breast-conserving surgery in Korean patients

    Breast Cancer Research and Treatment

    Ahn SG, Bae SJ, Lee HW, Yoon CI, Kim JW, Lee IJ, Jeong J

    Agosto de 2018

    Skin dose assessment with treatment planning system (TPS) and skin reaction evaluation of early breast cancer patients treated via an intraoperative radiation therapy (IORT) device

    Cambridge University Press

    Baziar O, Gholamhosseinian H, Forghani MN

    Abril de 2018

    Cosmetic outcome as rated by patients, doctors, nurses and BCCT.core software assessed over 5 years in a subset of patients in the TARGIT-A Trial

    BMC Cancer

    Corica T, Nowak AK, Saunders CM, Bulsara MK, Taylor M, Williams NR, Keshtgar M, Joseph DJ, Vaidya JS

    Abril de 2018

    Clinical analysis of early results of the implementation of intraoperative radiotherapy with the Intrabeam device during breast-conserving surgery of early breast cancer in a private hospital

    The Americal Society of Breast Surgeons

    Papa M, Keller O, Tova Y

    Dezembro de 2017

    Targeted Intraoperative Radiotherapy Tumour Bed Boost During Breast Conserving Surgery after Neoadjuvant Chemotherapy in HER2 Positive and Triple Negative Breast Cancer

    Reviews on Recent Clinical Trials

    Kolberg HC, Loevey G, Akpolat-Basci L, Stephanou M, Fasching PA, Untch M, Bulsara M, Vaidya JS, Liedtke C

    Dezembro de 2017

    Intraoperative Radiotherapy for Breast Cancer

    Frontiers in Oncology

    Harris EER, Small W

    Outubro de 2017

    Intraoperative Radiation for Breast Cancer with Intrabeam™: Factors Associated with Decreased Operative Times in Patients Having IORT for Breast Cancer

    Frontiers in Oncology

    Valente SA, Fanning A, Stewart RA, Grundfest S, Tendulkar RD, Cherian S, Shah C, Tu C, Yanda C, Radford D, Al-Hilli Z, Grobmyer SR

    Outubro de 2017

    Long-Term Cosmetic Outcome after Hypofractionated, Normofractionated, and Intraoperative Breast Radiation Therapy: A Photographic Evaluation Study

    International Journal of Radiation Oncology, Biology & Physics

    Ellethy T, Welzel G, Sperk E, Neumaier C, Ehmann M, Wenz F, Abo-Madyan Y

    Setembro de 2017

    Targeted Intraoperative Radiotherapy Tumour Bed Boost during Breast-Conserving Surgery after Neoadjuvant Chemotherapy - a Subgroup Analysis of Hormone Receptor-Positive HER2-Negative Breast Cancer

    KARGER/Breast Care

    Kolberg HC, Loevey G, Akpolat-Basci L, Stephanou M, Fasching PA, Untch M, Hoffmann O, Bulsara M, Vaidya JS, Liedtke C

    Agosto de 2017

    Keynote Address at the American Society of Breast Surgeons 18th Annual Meeting

    Annals of Surgical Oncology

    Wenz F

    Junho de 2017

    A multi-institutional analysis of intraoperative radiotherapy for early breast cancer: Does age matter

    The American Journal of Surgery

    Abbott AM, Valente SA, Loftus L, Tendulkar RD, Greif JM, Bethke KP, Donnelly ED, Lottich C, Ross DL, Friedman NB, Bedi CG, Joh JE,
    Kelemen P, Hoefer RA, Kang SK, Ruffer J, Police A, Fyles A, Graves GM, Willey SC, Tousimis EA, Small W, Lyons J, Grobmyer S, Laronga C

    Maio de 2017

    Hypofractionated, normofractionated and intraoperative breast irradiation: Long term cosmetic outcome based on photographic evaluation.

    Journal of Clinical Oncology

    Ellethy T, Welzel G, Sperk E, Neumaier C, Tuschy B, Berlit S, Ehmann M, Sütterlin M, Wenz FK, Abo-Madyan Y

    Maio de 2017

    TARGIT E(lderly): Prospective phase II study of intraoperative radiotherapy (IORT) in elderly patients with small breast cancer--3 year local control and overall survival

    Journal of Clinical Oncology

    Wenz FK

    Fevereiro de 2017

    Early complications after intraoperative radiotherapy revisited

    Journal of Surgical Oncology

    Holmes DR

    Janeiro de 2017

    Intraoperative radiotherapy (IORT) as boost in breast cancer

    Radioterapia

    Sedlmayer F, Reitsamer R, Wenz F, Sperk E, Fussl C, Kaiser J, Ziegler I, Zehentmayr F, Deutschmann H, Kopp P, Fastner G

    Novembro de 2016

    Targeted intraoperative radiotherapy tumour bed boost during breast-conserving surgery after neoadjuvant chemotherapy

    Strahlentherapie und Onkologie

    Kolberg HC, Loevey G, Akpolat-Basci L, Stephanou M, Fasching PA, Untch M, Liedtke C, Bulsara M, Vaidya JS

    Outubro de 2016

    Reduced Mortality With Partial-Breast Irradiation for Early Breast Cancer: A Meta-Analysis of Randomized Trials

    International Journal of Radiation Oncology, Biology & Physics

    Vaidya JS, Bulsara M, Wenz F, Coombs N, Singer J, Ebbs S, Massarut S, Saunders C, Douek M, Williams NR, Joseph DJ, Tobias JS, Baum M

    Setembro de 2016

    Cosmesis and Breast-Related Quality of Life Outcomes After Intraoperative Radiation Therapy for Early Breast Cancer: A Substudy of the TARGIT-A Trial

    International Journal of Radiation Oncology, Biology & Physics

    Corica T, Nowak AK, Saunders CM, Bulsara M, Taylor M, Vaidya JS, Baum M, Joseph DJ

    Janeiro de 2016

    Targeted Intraoperative Radiotherapy for the Management of Ductal Carcinoma In Situ of the Breast

    The Breast Journal

    Rivera R, Banks A, Casillas-Lopez A, Rashtian A, Lewinsky B, Sheth P, Hovannesian-Larsen L, Brousseau D, Iyengar G, Holmes DR

    Novembro de 2015

    Late Toxicity and Cosmetic Outcome Following Intraoperative Radiation Therapy As a Boost or As Accelerated Partial-Breast Irradiation: A Monocenter Experience

    International Journal of Radiation Oncology, Biology & Physics

    Key S, Miglinieri P, Vourch S, Miranda O, Mahlaire JP, Dupré PF, Pradier O, Schick U

    Novembro de 2015

    Targeted Intraoperative Radiotherapy for the Management of Ductal Carcinoma In Situ of the Breast

    The Breast Journal

    Rivera R, Banks A, Casillas-Lopez A, Rashtian A, Lewinsky B, Sheth P, Hovannesian-Larsen L, Brousseau D, Holmes DR

    Setembro de 2015

    Intraoperative Radiation Therapy (INTRABEAM) Experience at the Mastology Unit Leopoldo Aguerrevere Clinic

    Journal of Cancer Therapy

    Muñoz G, Hany R, Cosson A, Gonzalez C, Rasquií J, Rodriguez I, Ghaleb J, Gonzalez E, Benitez M, Hurtado W, Sanchez N, Figuera C

    Julho de 2015

    Pride, Prejudice, or Science: Attitudes Towards the Results of the TARGIT-A Trial of Targeted Intraoperative Radiation Therapy for Breast Cancer

    International Journal of Radiation Oncology, Biology & Physics

    Vaidya JS, Bulsara M, Wenz F, Joseph D, Saunders C, Massarut S, Flyger HL, Eiermann W, Alvarado M, Esserman L, Falzon M, Brew-Graves C, Potyka I, Tobias JS, Baum M

    Junho de 2015

    Targeted intraoperative radiotherapy in elderly patients (TARGIT-E) with early breast cancer; First safety analysis after 80 treated patients

    Strahlentherapie und Onkologie

    Neumaier C, Welzel G, Keller A, Abo-Madyan Y, Sperk E, Gerhardt A, Sütterlin M, Wenz F

    Maio de 2015

    Cosmetic outcome after breast conserving surgery and either external beam or intraoperative radiotherapy for early breast cancer: Objective assessment of patients from a randomized controlled trial in Lublin, Poland.

    Journal of Clinical Oncology

    Williams NR, Kurylcio A, Jankiewicz M, Romanek J, Polkowski W, Michalopoulos N, Keshtgar MR

    Maio de 2015

    Short term toxicity of intra-operative radiotherapy for patients with breast cancer treated at a single center

    Cancer Research

    Shai A, Zur M, Leviov M, Bitterman M, Eitan S, Steiner M

    Abril de 2015

    Low-kilovoltage single dose intraoperative radiation therapy for breast cancer

    Radiotherapy and Oncology

    Flores-Balcazar C, Santiago-Concha G, Sánchez-Castro R, Rosales-Pérez S, Bargalló-Rocha E, Rivera-Corona J

    Abril de 2015

    Whole breast radiotherapy does not affect growth of cancer foci in other quadrants: results from the TARGIT A trial

    Radiotherapy and Oncology

    Vaidya J, Bulsara M, Wenz F, Tobias JS, Joseph DJ, Massarut S, Flyger H, Eiermann W, Saunders C, Alvarado M, Brew-Graves C, Potyka I, Williams MR, Baum M

    Fevereiro de 2015

    Intraoperative Radiotherapy of the Breast for Early-Stage Breast Cancer: Ready for Primetime

    The Breast Journal

    Holmes DR

    Dezembro de 2014

    Intraoperative Boost Radiotherapy during Targeted Oncoplastic Breast Surgery: Overview and Single Center Experiences

    International Journal of Breast Cancer

    Malter W, Kirn V, Richters L, Fridrich C, Markiefka B, Bongartz R, Semrau R, Mallmann P, Kraemer S

    Julho de 2014

    A cohort analysis to identify eligible patients for intraoperative radiotherapy (IORT) of early breast cancer

    Radioterapia

    Sperk E, Astor D, Keller A, Welzel G, Gerhardt A, Tuschy B, Sütterlin M, Wenz F

    Maio de 2014

    Cosmetic outcome within one year of breast-conserving surgery, after external beam or intraoperative radiotherapy for early breast cancer: Objective assessment of patients from a randomized controlled trial.

    Journal of Clinical Oncology

    Williams NR, Wenz F, Welzel G, Michalopoulos N, Keshtgar MR

    Fevereiro de 2014

    Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial

    The Lancet

    Vaidya JS, Wenz F, Bulsara M, Tobias JS, Joseph DJ, Keshtgar M, Flyger HL, Massarut S, Alvarado M, Saunders C, Eiermann W, Metaxas M, Sperk E, Sütterlin M, Brown D, Esserman L, Roncadin M, Thompson A, Dewar JA, Holtveg HMR, Pigorsch S, Falzon M, Harris E, Matthews A, Brew-Graves C, Potyka I, Corica T, Williams NR, Baum M

    Junho de 2013

    Cost-Effectiveness Analysis of Intraoperative Radiation Therapy for Early-Stage Breast Cancer

    Annals of Surgical Oncology

    Alvarado MD, Mohan AJ, Esserman LJ, Park CC, Harrison BL, Howe RJ, Thorsen C Ozanne EM

    Julho de 2012

    Late radiation toxicity after intraoperative radiotherapy (IORT) for breast cancer: results from the randomized phase III trial TARGIT A

    Breast Cancer Research and Treatment

    Sperk E, Welzel G, Keller A, Kraus-Tiefenbacher U, Gerhardt A, Sütterlin M, Wenz F

    Maio de 2012

    TARGIT-E(lderly)--Prospective phase II study of intraoperative radiotherapy (IORT) in elderly patients with small breast cancer

    BMC Cancer

    Neumaier C, Sperk E, Welzel G, Xasser A, Kraus-Tiefenbacher U, Keller A, Gerhardt A, Sütterlin M,
    Wenz F

    Maio de 2011

    Targeted Intraoperative Radiotherapy for Breast Cancer in Patients in Whom External Beam Radiation Is Not Possible

    International Journal of Radiation Oncology, Biology & Physics

    Keshtgar MRS, Vaidya JS, Tobias JS, Wenz F, Joseph D, Stacey C, Metaxas MG, Keller A, Corica T, Williams NR, Baum M

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    The Use of Re-irradiation in Locally Recurrent, Non-metastatic Rectal Cancer
    Radioterapia
    Susko M, Lee J, Salama J, Thomas S, Uronis H, Hsu D, Migaly J, Willett C, Czito B, Palta M
    Março de 2016
    Intraoperative radiotherapy with low energy photons in recurrent colorectal cancer: a single centre retrospective study
    Texto completo
    Contemporary Oncology
    Skórzewska M, Mielko J, Kurylcio A, Romanek J, Polkowski WP
    Abril de 2015
    Intraoperative radiotherapy in locally-advanced and recurrent rectal cancer: retrospective review of 68 cases
    Translational Cancer Research
    Potemin S, Uvarov I, Vasilenko I
    Novembro de 2013
    Intraoperative Radiotherapy with Low-Energy Photons in Rectal Cancer Recurrence
    Targeted Intraoperative Radiotherapy in Oncology (Book)
    Polkowski WP, Skórzewska M
    Julho de 2012
    Intraoperative radiation therapy with the photon radiosurgery system in locally advanced and recurrent rectal cancer: retrospective review of the Cleveland clinic experience
    Radioterapia
    Guo S, Reddy CA, Kolar M, Woody N, Mahadevan A, Deibel F, Dietz DW, Remzi FH, Suh JH
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    Título
    Link
    Publicação
    Autores

    Fevereiro de 2025

    Long term effectiveness of intraoperative radiotherapy given as a boost in adjuvant treatment for oral cavity cancers

    Scientific Reports

    Woźniak G, Rutkowski T, Majewski W, Napieralska A, Wydmański J, Czarniecka A, Szymczyk C, Bekman A, Kaniszewska Dorsz Ż, Latusek T, Maciejewski B

    Junho de 2022

    Intraoperative radiation therapy for locally advanced and recurrent head and neck cancer

    Journal of Clinical Oncology

    Chiodo C, Gros S, Lee B, Block AM, Emami B, Small W, Abdelrhman TR

    Dezembro de 2016
    Intraoperative radiation therapy (IORT) in head and neck cancer: A systematic review
    Medicine
    Kyrgias G, Hajiioannou J, Tolia M, Kouloulias V, Lachanas V, Skoulakis C, Skarlatos I, Rapidis A, Bizakis I
    Abril de 2016
    Intra-operative radiation therapy (IORT) in recurrent head and neck cancer
    Oral Oncology
    De Felice F, Musio D, Tombolini V
    Abril de 2015
    Intraoperative radiotherapy (IORT) in the treatment of head and neck cancer
    Translational Cancer Research
    Münter MW, Köppen U, Ramuscak A, Sittel C, Wegner N
    Dezembro de 2013
    Current advances in radiotherapy of head and neck malignancies
    Journal of International Oral Health
    Roopashri G, Baig M
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    Título
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    Autores

    Novembro de 2022

    A case report on a novel use of intraoperative Intrabeam™ radiation therapy for a recurrent malignant peripheral nerve sheath tumor with sciatic nerve involvement

    Radioterapia

    Chaharbakhshi E, Hardham J, Siochi RA, Tenenholz TC, Lindsey BA

    Outubro de 2021 

    Electronic brachytherapy for treatment of non-melanoma skin cancers: clinical results and toxicities

    Journal of Contemporary Brachytherapy

    Goyal U, Cheung MK, Suszko J, Laughlin B, Kim Y, Askam J, Arif-Tiwari H, Slane B, Gordon J, Stea B

    Setembro de 2019
    Intraoperative Radiotherapy with Low Energy x-Rays for Primary and Recurrent Soft-Tissue Sarcoma
    International Journal of Radiation Oncology, Biology & Physics

    Sarria GR, Petrova V, Abo-Madyan Y, Wenz F, Hohenberger P, Sperk E, Giordano FA

     

     

    Dezembro de 2012
    Superficial x-ray in the treatment of basal and squamous cell carcinomas: A viable option in select patients
    Journal of the American Academy of Dermatology
    Cognetta AB, Howard BM, Heaton HP, Stoddard ER, Hong HG, Green W H
    Março de 2012
    Radiation Therapy and Skin Cancer
    Modern Practices in Radiation Therapy
    Tward JD, Anker CJ. Gaffney DK, Bowen G
    Maio de 2003
    Use of Low-Energy X-Rays in the Treatment of Superficial Nonmelanomatous Skin Cancers
    Cancer Investigation
    Bodner WR, Hilaris BS, Alagheband M, Safai B, Mastoras CA, Saraf S

Física médica, pesquisa translacional e tecnologia

  • Ano
    Título
    Link
    Publicação
    Autores

    Novembro de 2024

    Technical note: Determination of CQ for a miniature x-ray source using a soft x-ray ionization chamber calibrated in NIST reference beam qualities

    Medical Physics

    Watson PGF, Davis S, Culberson WS

    Março de 2024

    Intraoperative radiation therapy with 50 kV x-rays: A multi-institutional review

    Journal of Applied Clinical Medical Physics

    Sethi A, Gros S, Brodin P, Ghavidel B, Chai X, Popovic M, Tomé WA, Trichter S, Yang X, Zhang H, Uhl V

    Março de 2023

    Dosimetric evaluation of an intraoperative radiotherapy system: a measurement-based and Monte-Carlo modelling investigation

    National Library of Medicine

    Chin M, Rowshanfarzad P, Neveri G, Ebert MA, Pfefferlé D

    Dezembro de 2021
    Gold-nanoparticle-enriched breast tissue in breast cancer treatment using the INTRABEAM system: a Monte Carlo study
    Radiation and Environmental Biophysics
    Tegaw EM, Geraily G, Gholami S, Shojaei M, Tadesse GF
    Novembro 2021
    Monte Carlo calculation of the TG-43 dosimetry parameters for the INTRABEAM source with spherical applicators
    Physics in Medicine & Biology
    Alvarez DSA, Watson P, Popovic M, Heng VJ, Evans M, Seuntjens J
    Março de 2021
    Patient-Specific Quality Assurance Using a 3D-Printed Chest Phantom for Intraoperative Radiotherapy in Breast Cancer
    Frontiers in Oncology
    Choi Y, Lee IJ, Park K, Park KR, Cho Y, Kim JW, Lee H
    Fevereiro de 2021
    A Comparison between Electron Gamma Shower, National Research Council/Easy Particle Propagation (EgSnrc/Epp) and Monte Carlo N-Particle Transport Code (MCNP) in Simulation of the INTRABEAM System with Spherical Applicators
    Journal of Biomedical Physics and Engineering
    Tegaw EM, Geraily GH, Etesami SM, Gholami S, Ghanbari H, Farzin M, Tadesse GF, Shojaei M
    Janeiro de 2021
    Effective energy assessment during breast cancer intraoperative radiotherapy by low-energy X-rays: A Monte Carlo study
    Radiation and Environmental Biophysics
    Shamsabadi R, Baghani HR, Mowlavi AA, Azadegan B
    Abril de 2020
    Dose-rate considerations for the INTRABEAM electronic brachytherapy system: Report from the American association of physicists in medicine task group no. 292
    Medical Physics
    Culberson WS, Davis SD, Gwe‐Ya Kim G, Lowenstein JR, Ouhib Z, Popovic M, Waldron TJ, Safigholi H, Simiele SJ, Rivard MJ
    Fevereiro de 2020
    Dosimetric evaluation of incorporating the revised V4.0 calibration protocol for breast intraoperative radiotherapy with the INTRABEAM system
    Journal of Applied Clinical Medical Physics
    Shaikh MY, Burmeister J, Scott R, Kumaraswamy LK, Nalichowski A, Joiner MC
    Março de 2018
    Intraoperative Radiotherapy With INTRABEAM: Technical and Dosimetric Considerations
    Frontiers in Oncology
    Sethi A, Emami B, Small W, Thomas TO
    Maio de 2015
    Dosimetric characterization of INTRABEAM® miniature accelerator flat and surface applicators for dermatologic applications
    Medica Physica
    Goubert M, Parent L
    Setembro de 2014
    Radiation protection for an intraoperative X-ray source compared to C-arm fluoroscopyStrahlenschutz einer Röntgenquelle zur intraoperativen Strahlentherapie im Vergleich mit C-Bogen-Durchleuchtung
    Zeitschrift für Medizinische Physik
    Schneider F, Clausen S, Jahnke A, Steil V, Bludau F, Sütterlin M, Obertacke U, Wenz F
    Janeiro de 2014
    Radiation protection for an intra-operative X-ray devicer an intra-operative X-ray device
    The British Journal of Radiology
    Eaton DJ, Gonzalez R, Duck S, Keshtgar M
    Janeiro de 2014
    A novel approach for superficial intraoperative radiotherapy (IORT) using a 50 kV X-ray source: a technical and case report
    Journal of Applied Clinical Medical Physics
    Schneider F, Clausen S, Thölking J, Wenz F, Abo-Madyan Y
    Outubro de 2012
    Quality assurance and independent dosimetry for an intraoperative x-ray device
    Medical Physics
    Eaton DJ
    Novembro de 2011
    Development of a Novel Method for Intraoperative Radiotherapy During Kyphoplasty for Spinal Metastases (Kypho-IORT)
    International Journal of Radiation Oncology, Biology & Physics
    Schneider F, Greineck F, Clausen S, Mai S, Obertacke U, Reis T, Wenz F
  • Ano
    Título
    Link
    Publicação
    Autores

    Novembro de 2025

    A prospective observational study of inflammatory mediators in cerebrospinal fluid after intraoperative radiotherapy of brain tumors

    Therapeutic Advances in Medical Oncology

    Shiban E, Krauss P, Schaller T, Konietzko I, Mögele T, Jungbäck N, Mielke D, Märkl B, Kahl KH, Mielewczyk Z, Liesche-Starnecker F

    Novembro de 2022

    Biological and clinical review of IORT-induced wound fluid in breast cancer patients

    Front Oncol.

    Jeibouei S, Shams F, Mohebichamkhorami F, Sanooghi D, Faal B, Akbari ME, Zali H

    Junho de 2022

    The impact of intraoperative radiotherapy on breast cancer: focus on the levels of angiogenic factors

    World Journal of Surgical Oncology

    Nafissi N, Mohammadlou M, Akbari ME, Mahdavi SR, Sheikh M, Borji M, Babaee E, Baharlou R

    Janeiro de 2021
    Changes in peripheral immune cells after intraoperative radiation therapy in low-risk breast cancer
    Journal of Radiation Research
    Linares-Galiana I, Berenguer-Frances MA, Cañas-Cortés R, Pujol-Canadell M,Comas-Antón S,Martínez E, Laplana M, Pérez-Montero H, Pla-Farnós MJ, Navarro-Martin A,Nuñez M ,Both B, Guedea F 
    Abril de 2021
    Wound Fluid from Breast Cancer Patients Undergoing Intraoperative Radiotherapy Exhibits an Altered Cytokine Profile and Impairs Mesenchymal Stromal Cell Function
    Cancers (Basel)
    Wuhrer A , Uhlig S ,Tuschy B,Berlit S ,Sperk E , Bieback K, Sütterlin M
    Agosto de 2020
    Cardiac serum marker alterations after intraoperative radiotherapy with low-energy x-rays in early breast cancer as an indicator of possible cardiac toxicity
    Strahlentherapie und Onkologie
    Stefanovic S, Berlit S, Sperk E, Wenz F, Weiß C, Trinkmann F, Sütterlin M, Tuschy B
    Fevereiro de 2020
    Intraoperative radiotherapy for breast cancer treatment efficiently targets the tumor bed preventing breast adipose stromal cell outgrowth
    Strahlentherapie und Onkologie
    Uhlig S, Wuhrer A, Berlit S, Tuschy B, Sütterlin M, Bieback K
    Fevereiro de 2020
    Surgical Wound Fluids from Patients with Breast Cancer Reveal Similarities in the Biological Response Induced by Intraoperative Radiation Therapy and the Radiation-Induced Bystander Effect—Transcriptomic Approach
    International Journal of Molecular Sciences
    Kulcenty K, Piotrowski I, Rucinski M, Wroblewska JP, Jopek K, Murawa D, Suchorska WM
    Janeiro de 2017
    Biology of high single doses of IORT: RBE, 5 R’s, and other biological aspects
    Radioterapia
    Herskind C, Ma L, Liu Q, Zhang B, Schneider F, Veldwijk MR, Wenz F
    Abril de 2015
    Tissue inhomogeneity corrections in low-kV intra-operative radiotherapy (IORT)
    Translational Cancer Research
    Sethi A, Chinsky B, Gros S, Diak A
    Abril de 2015
    Beyond the linear quadratic model: intraoperative radiotherapy and normal tissue tolerance
    Translational Cancer Research
    Emami B, Woloschak G, Small W
    Fevereiro de 2014
    Radiobiological aspects of intraoperative tumour-bed irradiation with low-energy X-rays (LEX-IORT)
    Translational Cancer Research
    Herskind C, Wenz F
    Fevereiro de 2014
    Cell and molecular response to IORT treatment
    International Journal of Radiation Oncology, Biology & Physics
    Minafra L, Bravatà V
    Fevereiro de 2014
    Immune effects of high dose radiation treatment: implications of ionizing radiation on the development of bystander and abscopal effects
    Translational Cancer Research
    Sologuren I, Rodríguez-gallego C, Lara PC
    Setembro de 2013
    Mitogenic signalling in the absence of epidermal growth factor receptor activation in a human glioblastoma cell line
    Journal of Neuro-Oncology
    Wang M, Maier P, Wenz F, Giordano FA, Herskind C
    Março de 2013
    Mitogenic signalling in the absence of epidermal growth factor receptor activation in a human glioblastoma cell line
    International Journal of Radiation Oncology, Biology & Physics
    Liu Q, Schneider F, Ma L, Wenz F, Herskind C
    Dezembro de 2008
    Sphere of Equivalence - A Novel Target Volume Concept for Intraoperative Radiotherapy Using Low-Energy X Rays
    International Journal of Radiation Oncology, Biology & Physics
    Herskind C, Griebel J, Kraus-Tiefenbacher U, Wenz F
    Março de 2008
    Targeted Intraoperative Radiotherapy Impairs the Stimulation of Breast Cancer Cell Proliferation and Invasion Caused by Surgical Wounding
    Clinical Cancer Research
    Belletti B, Vaidya JS, D’Andrea S, Entschladen F, Roncadin M, Lovat F, Berton S, Perin T, Candiani E, Reccanello S, Veronesi A, Canzonieri V, Trovò MG, Zaenker KS, Colombatti A, Baldassarre G, Massarut S
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    Título
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    Publicação
    Autores
    Abril de 2015
    Electronic brachytherapy—current status and future directions
    The British Journal of Radiology
    Eaton DJ

Qualidade de vida e cosmese

  • Ano
    Título
    Link
    Publicação
    Autores

    Agosto de 2024

    Qualitative exploration of patients' experiences with Intrabeam TARGeted Intraoperative radioTherapy (TARGIT-IORT) and External-Beam RadioTherapy Treatment (EBRT) for breast cancer

    BMJ Open

    Bagga SK, Swiderska N, Hooker C, Royle J, Ennis-O'Connor M, Freeney S, Watson D, Woolcock R, Lodge G, Laws S, Vaidya JS

    Janeiro de 2019
    Patient preferences for adjuvant radiotherapy in early breast cancer are strongly influenced by treatment received through random assignment
    European Journal of Cancer Care
    Corica T, Saunders CM, Bulsara MK, Taylor M, Joseph DJ, Nowak AK

    Dezembro de 2018

    A Prospective Analysis of Quality of Life and Toxicity Outcomes in Treating Early Breast Cancer With Breast Conservation Therapy and Intraoperative Radiation Therapy

    Frontiers in Oncology

    Sosin M, Gupta SS, Wang JS, Costellic CD, Gulla A, Bartholomew AJ, O'Neill SC, Hechenbleikner EM, Collins BT, Rudra S, Collins SP, Chaldekas KM, Seevaratnam S, Langan RC, Willey SC, Tousimis EA

    Julho de 2017
    Intraoperative radiotherapy: Patient selection, management, and follow-up
    Journal of Surgical Oncology
    Holmes DR, Zimmerman R
    Setembro de 2016
    Cosmesis and Breast-Related Quality of Life Outcomes After Intraoperative Radiation Therapy for Early Breast Cancer: A Substudy of the TARGIT-A Trial
    International Journal of Radiation Oncology, Biology & Physics
    Corica T, Nowak AK, Saunders CM, Bulsara M, Taylor M, Vaidya JS, Baum M, Joseph DJ
    Maio de 2016
    Environmental and social benefits of the targeted intraoperative radiotherapy for breast cancer: data from UK TARGIT-A trial centres and two UK NHS hospitals offering TARGIT IORT
    The BMJ
    Coombs NJ, Coombs JM, Vaidya UJ, Singer J, Bulsara M, Tobias JS, Wenz F, Joseph DJ, Brown DA, Rainsbury R, Davidson T, Adamson DJA, Massarut S, Morgan D, Potyka I, Corica T, Falzon M, Williams N, Baum M, Vaidya JS
    Fevereiro de 2014
    Comparison of mammographic findings after intraoperative radiotherapy or external beam whole breast radiotherapy
    European Journal of Surgical Oncology
    Elsberger B, Romsauerova A, Vinnicombe S, Whelehan P, Brown DC, Dewar JA, Thompson AM, Evans, A
    Novembro de 2013
    Patient preferences regarding intraoperative versus external beam radiotherapy following breast-conserving surgery
    Breast Cancer Research and Treatment
    Alvarado MD, Conolly J, Park C, Sakata T, Mohan AJ, Harrison BL, Hayes M, Esserman LJ, Ozanne EM
    Março de 2013
    Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer
    The New England Journal of Medicine
    Darby SC, Ewertz M, McGale P, Bennet AM, Blom-Goldman U, Brønnum D, Correa C, Cutter D, Gagliardi G, Gigante B, Jensen M-B, Nisbet A, Peto R, Rahimi K, Taylor C, Hall P
    Janeiro de 2013
    Radiation-related quality of life parameters after targeted intraoperative radiotherapy versus whole breast radiotherapy in patients with breast cancer: results from the randomized phase III trial TARGIT-A
    Radioterapia
    Welzel G, Boch A, Sperk E, Hofmann F, Kraus-Tiefenbacher U, Gerhardt A, Wenz F
    Fevereiro de 2012
    Persistent pain after targeted intraoperative radiotherapy (TARGIT) or external breast radiotherapy for breast cancer: A randomized trial
    The Breast
    Andersen KG, Gärtner R, Kroman N, Flyger H, Kehlet H
  • Ano
    Título
    Link
    Publicação
    Autores

    Janeiro de 2024

    Clinical Outcomes of Breast-Conserving Surgery with Synchronous 50-kV X-ray Intraoperative Partial Breast Irradiation in Patients Aged 64 Years or Older with Low-Risk Breast Cancer

    Breast Cancer (Auckl)

    Salari K, Glaza A, Lee JS, Sarvepalli N, Dekhne N, Kiran SH, Chen PY, Dilworth JT

    Julho de 2023

    Longitudinal cosmetic outcome after planned IORT boost with low kV X-rays-monocentric results from the TARGIT BQR registry

    National Library of Medicine

    Goerdt L, Poemsl J, Spaich S, Welzel G, Abo-Madyan Y, Ehmann M, Berlit S, Tuschy B, Sütterlin M, Wenz F, Sperk E

    Novembro 2021

    Surgical and Oncologic Outcomes With Intraoperative Radiation Therapy for Early Breast Cancer

    The American Surgeon

    Friedman-Eldar O, Layton C, De Castro Silva I, Moller MG, Allen A, Franceschi D, Isrow D, Samuels S, Takita C, Avisar E

    Junho de 2021

    Hypofractionated whole breast irradiation after IORT treatment is safe in patients receiving adjuvant chemotherpy

    Clinical and Translational Oncology

    Burgos-Burgos J, Vega V, Macias-Verde D, Gómez V, Travieso-Aja M, Travieso J, Vicente E, Murias C, Santana C, Ospina J, Lara PC

    Abril de 2018
    Cosmetic outcome as rated by patients, doctors, nurses and BCCT.core software assessed over 5 years in a subset of patients in the TARGIT-A Trial
    Radioterapia
    Corica T, Nowak AK, Saunders CM, Bulsara MK, Taylor M, Williams NR, Keshtgar M, Joseph DJ, Vaidya JS
    Dezembro de 2017
    Aesthetic outcome after breast conserving surgery and either intraoperative radiotherapy or whole breast external beam radiotherapy for early breast cancer: objective assessment of patients in a randomized controlled trial in Lublin, Poland
    European Journal of Gynaecological Oncology
    Williams N, Kurylcio A, Jankiewicz M, Romanek J, Polkowski W, Michalopoulos N, Keshtgar M
    Fevereiro de 2014
    Oncoplastic breast reconstruction after IORT
    Translational Cancer Research
    Malter W, Kirn V, Mallmann P, Kraemer S
    Julho de 2013
    Objective assessment of cosmetic outcome after targeted intraoperative radiotherapy in breast cancer: results from a randomised controlled trial
    Breast Cancer Research and Treatment
    Keshtgar MRS, Williams NR, Bulsara M, Saunders C, Flyger H, Cardoso JS, Corica T, Bentzon N, Michalopoulos NV, Joseph DJ

Diretrizes, recomendações e ATS

  • Ano
    Título
    Link
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    Autores

    Novembro de 2023

    Partial Breast Irradiation for Patients With Early-Stage Invasive Breast Cancer or Ductal Carcinoma In Situ: An ASTRO Clinical Practice Guideline

    Practical Radiation Oncology

    ASTRO

    Abril de 2023

    Diagnosis and Treatment of Patients with early and advanced Breast Cancer - Adjuvant Radiotherapy

    AGO

    AGO

    Outubro de 2021

    Traitements locorégionaux des cancers du sein infiltrants non métastatiques - Synthèse

    INCa

    INCa

    Setembro de 2021
    Radioterapia intraoperatória (IORT)
    AETNA
    AETNA
    2020
    NCCN Guidelines
    NCCN
    NCCN
    2020
    Leitlinienprogramm Onkologie: S3-Leitlinie Früherkennung, Diagnose, Therapie und Nachsorge des Mammakarzinoms
    Leitlinienprogramm Onkologie
    Leitlinienprogramm Onkologie
    Agosto de 2019
    Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    Annals of Oncology
    Cardoso F, Kyriakides S, Ohno S, Penault-Llorca F, Poortmans P, Rubio IT, Zackrisson S, Senkus E
    Junho de 2018
    Radiation therapy for the whole breast: Executive summary of an American Society for Radiation Oncology (ASTRO) evidence-based guideline
    Practical Radiation Oncology
    Smith BD, Bellon JR, Blitzblau R, Freedman G, Haffty B, Hahn C, Halberg F, Hoffman K, Horst K, Moran J, Patton C, Perlmutter J, Warren L, Whelan T, Wright JL, Jagsi R
    Janeiro de 2018
    Intrabeam radiotherapy system for adjuvant treatment of early breast cancer Technology appraisal guidance [TA501]
    NICE
    NICE
    Janeiro de 2016
    ESTRO-ACROP guideline “target delineation of glioblastomas”
    Radiotherapy and Oncology
    Niyazi M, Brada M, Chalmers AJ, Combs SE, Erridge SC, Fiorentino A, Grosu AL, Lagerwaard FJ, Minniti G, Mirimanoff R-O, Ricardi U, Short SC, Weber DC, Belka C
    Setembro de 2012
    Radiotherapeutic and surgical management for newly diagnosed brain metastasis(es): An American Society for Radiation Oncology evidence-based guideline
    Practical Radiation Oncology
    Tsao MN, Rades D, Wirth A, Lo SS, Danielson BL, Gaspar LE, Sperduto PW, Vogelbaum MA, Radawski JD, Wang JZ, Gillin MT, Mohideen N, Hahn CA, Chang EL
  • Ano
    Título
    Link
    Publicação
    Autores

    Julho de 2023

    First Spanish consensus on the use of intraoperative radiotherapy in breast cancer. Conclusions of the expert panel

    Revista de Senología y Patología Mamaria

    SESPM - SEOR

    Março de 2010
    Patient selection for accelerated partial-breast irradiation (APBI) after breast-conserving surgery: Recommendations of the Groupe Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) breast cancer working group based on clinical evidence (2009)
    Radiotherapy and Oncology
    Polgár C, Van Limbergen E, Pötter R, Kovács G, Polo A, Lyczek J, Hildebrandt G, Niehoff P, Guinot JL, Guedea F, Johansson B, Ott OJ, Major T, Strnad V
  • Ano
    Título
    Link
    Publicação
    Autores
    Setembro de 2016
    An international randomised controlled trial to compare TARGeted Intraoperative radioTherapy (TARGIT) with conventional postoperative radiotherapy after breast-conserving surgery for women with early-stage breast cancer (the TARGIT-A trial)
    Health Technology Assessment 
    Vaidya JS, Wenz F, Bulsara M, Tobias JS, Joseph DJ, Saunders C, Brew-Graves C, Potyka I, Morris S, Vaidya HJ, Williams NR, Baum M
    Setembro de 2015
    The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation
    Health Technology Assessment 
    Picot J, Copley V, Colquitt JL, Kalita N, Hartwell D, Bryant J

Diversos

  • Cabeçalho da coluna
    Cabeçalho da coluna
    Ano
    Título
    Texto do link
    Publicação
    Autores

    Janeiro de 2021

    Single-Fraction Adjuvant Electronic Brachytherapy after Resection of Conjunctival Carcinoma

    Cancers (Basel)

    Sarria GR, Serpa S, Buitrago M, Fuentes Rivera P, Ramirez D, Giordano FA, Sarria GJ

    Setembro de 2020
    Adjuvant electronic brachytherapy for endometrical carcinoma: A 4-year outcomes report
    Brachytherapy
    Sarria GR, Sperk E, Wenz F, Schneider F, Abo-Madyan Y, Giordano FA, Ehmann M
    Julho de 2020
    Safety and efficacy of INTRABEAM intraoperative radiotherapy for invasive thymoma
    Medicine
    Cui T, Dai J, Li J, Qian J, Li G, Sun J

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