ZEISS expands DORC portfolio and further strengthens digital footprint with improved workflow efficiency and digital visualization

Showcasing at AAO 2025:

• NEW 510k CLEARANCE SUPPORTS MORE INFORMED DECISION MAKING & PATHOLOGY DETECTION: Showcasing optical coherence tomography angiography (OCT-A) with ZEISS CIRRUS AngioPlex^® with noninvasive imaging of the retinal and choroidal vasculature; now with 510k clearance and CE approval, ICGA for CLARUS^® 700 offers FA + ICG simultaneous capture.
• OPTIMIZED RETINAL SURGICAL EXPERIENCE: Announcing updates to DORC instruments to expand surgeons’ options, including new gauges added to the range of subretinal injection cannulae and a new Midfield endoillumination light probe with directed light; updated CALLISTO eye^® software on the ZEISS ARTEVO 850 and ZEISS ARTEVO 750 supports increased visualization.
• IMPROVED GLAUCOMA MANAGEMENT FOR CATARACT PATIENTS: Demonstrating a fully integrated diagnostic and treatment solution for managing comorbid cataract/glaucoma patients to support more efficient and confident decision making.
• ENHANCED OPHTHALMIC RESEARCH AND COLLABORATION: Featuring the AI-ready ZEISS Research Data Platform (RDP), which can empower retina specialists to transform their clinical hypotheses into measurable outcomes; previewing the next evolution of browser-based digital data management which aggregates clinical data at scale, powers advanced analytics, and enables seamless collaboration across eye care professionals for more personalized patient care delivery.
• REFRACTIVE INDUSTRY MILESTONE: Celebrating more than 12 million eyes treated with ZEISS SMILE and ZEISS SMILE pro.
  

Jena, Germany / Dublin, CA | October 7, 2025 | Carl Zeiss Meditec AG

ZEISS Medical Technology will showcase its latest enhancements in ophthalmic visualization and digital workflow innovation at the American Academy of Ophthalmology (AAO) conference from Oct. 18 - 20, 2025, in Orlando, FL.

"ZEISS continues to be at the forefront of optical and digital innovation, advancing our clinical workflows to be more efficient and empowering for doctors and surgeons around the world to deliver more precise and personalized care for their patients," says Magnus Reibenspiess, Head of Strategic Business Unit Ophthalmology at ZEISS Medical Technology.

"We’re delivering important enhancements to our expanding portfolio across ZEISS and DORC solutions to meet the growing needs of ophthalmologists worldwide," said PT Cheong, Head of Global Sales for Ophthalmology, ZEISS Medical Technology. "From diagnostics to surgery and post-op management, our advanced technology solutions support more confident, personalized patient care."

The ZEISS Retina Workflow offers a digitally connected solution from diagnostics through surgery and post-op care, supporting healthcare professionals in advancing retinal care with enhanced data continuity, procedural efficiency, and clinical decision-making across the retina care pathway.

At AAO, ZEISS will showcase multiple diagnostic enhancements supporting improved decision making and pathology detection through gold-standard imaging technology. Now with 510k clearance and CE approval¹, the CLARUS^® 700 with ICGA provides high-resolution early-phase to late-phase ultra-widefield imaging. New features include standalone ICG, simultaneous FA-ICG capture, and an added movie mode for all angiography modalities: standalone FA, standalone ICG, and simultaneous FA-ICG. These advancements underscore ZEISS's commitment to delivering cutting-edge solutions that enhance clinical outcomes and streamline the diagnostic process for healthcare professionals.

Additionally, this year marks the 100-year anniversary of advancements in ZEISS fundus imaging. In 1926, ZEISS and Johan Nordenson released the first commercially available fundus camera, laying the foundation for a century of innovation in ocular imaging technology.

ZEISS will also showcase its latest in OCT technology, providing enhanced details and insights to assist eyecare practitioners when examining patients and managing diseases. The implementation of best practices is helpful to maximize the clinical utility of OCT-A. In recognition of this, ZEISS has released OCT-A Simplified, a step-by-step eBook by Ricardo Luz Leitão Guerra, MD, MSc, FICO. The guidebook makes OCT-A more accessible to eyecare practitioners, covering image acquisition, analysis, and interpretation providing practical insights clinicians can apply immediately in clinical decision-making. Copies of the OCT-A Simplified ebook will be available at AAO at the ZEISS booth #2261.

ZEISS continues to offer the latest in OCT solutions, most recently gaining CE mark for CIRRUS PathFinder, an innovative clinical support tool with artificial intelligence (AI) fully integrated to enable more confident decision-making and accelerate a clinician’s patient care workflow with OCT interpretation assistance, supporting improved surgical planning, particularly for high-volume clinics.

To further optimize the surgical experience for vitreoretinal surgeons, ZEISS will showcase new updates² to its DORC instrument portfolio within the ZEISS Retinal Workflow.

• New gauges added to the company’s range of subretinal injection cannulae: 25G and 27G.³ The subretinal cannulas are designed for injection of fluids and/or gases into subretinal space and feature a 41G extendible tip for a smooth and uninterrupted sliding motion. The range is compatible with EVA NEXUS's INICIO micro-injection system. EVA NEXUS is the only system cleared by the FDA for subretinal injection in the U.S.
• The new Midfield endoillumination light probe⁴ with directed light. The light probe provides a homogeneous field of illumination of about 60° with sharply defined edges, enabling surgeons to effectively distinguish between different media, such as vitreous, BSS and air. The new light probe is also suitable for trans-scleral illumination and comes with a trans-scleral depressor as standard. The probe is available in three gauges: 23G, 25G and 27G.⁵
• The DORC EVA NEXUS™ platform, uniquely suited to address both retina and cataract surgery, is now available with angled EquiPhaco designed for optimal irrigation flow. EquiPhaco, combined with EVA NEXUS SMART IOP™, allows for a more stable, lower anterior chamber pressure during procedures.

Lastly, ZEISS will showcase its updated CALLISTO eye^® software for ZEISS ARTEVO 750 and ZEISS ARTEVO 850, allowing for visualization of retinal structures on the 3D screen of the ZEISS ARTEVO 850 with up to 30% higher magnification⁶. Advanced camera settings, including automatic exposure control, provide customization of the visualization experience to a surgeon’s individual preferences. In addition, the software update now also offers reference image matching for toric IOL implantations in either the eyepiece of the ZEISS ARTEVO 750 or the 3D monitor of the ZEISS ARTEVO 850 as well as optional 3D recording on the ZEISS ARTEVO 850.

ZEISS diagnostic and digital solutions integrated into surgical ophthalmic workflows can help surgeons visualize more, connect insights across a workflow, and make data-driven decisions, including earlier detection of eye conditions that may affect surgical planning and outcomes. At AAO, ZEISS will demonstrate a fully integrated solution connecting cataract and glaucoma workflows to support more efficient and confident decision making.

Glaucoma is the most common comorbidity in cataract surgery. According to a recent study⁷, around 20% of patients who undergo cataract procedures also have glaucoma or ocular hypertension. ZEISS offers integrated diagnostic and therapeutic solutions to support earlier detection and management of glaucoma in cataract patients, helping to improve long-term outcomes of cataract surgery. Devices including the ZEISS SL 800, CLARUS^®, CIRRUS^® OCT, ARTEVO^® 750, and VISULAS^® are shared across the cataract and glaucoma workflows and seamlessly connected via FORUM^® for complete data continuity.

At AAO, the company will feature the ZEISS Research Data Platform (RDP), a secure, cloud-based, AI-driven solution designed for multi-center research and real-world clinical evidence, enabling retina specialists to translate their clinical hypotheses into measurable outcomes. With built-in support for AI algorithm training and biomarker generation, the ZEISS RDP allows researchers to harness complex data and drive innovation without compromising on compliance or collaboration.

ZEISS will also preview the next evolution of browser-based digital data management solution that seamlessly integrates with EMR systems to aggregate essential medical data and can connect diagnostic data from ZEISS and non-ZEISS devices. The solution provides actionable clinical insights through color-coded alerts, trend analysis for OCT and Visual Field data, and interactive analyses. Offered in flexible subscription packages, providers can select the configuration that fits their practice needs.

ZEISS continues to extend its global, refractive momentum with the celebration of more than 12 million eyes treated with SMILE^® and SMILE^® pro, reflecting the growing international adoption of safe and effective lenticule extraction solutions. ZEISS SMILE and ZEISS SMILE pro continue to be leading solutions trusted by surgeons for the technology’s proven reliability and effective treatment with the VisuMax^® and VISUMAX^® 800 from ZEISS.

ZEISS will showcase its latest offerings and new innovations at the American Academy of Ophthalmology (AAO) conference from Oct. 18 - 20, 2025, in Orlando, FL, at booth #2261.

For more information, visit www.zeiss.com/med.