C. Elegans

C. elegans embryos are sensitive and require gentle imaging to follow rapid developmental events. ZEISS Lightsheet 7 and Lattice Lightsheet systems enable long-term, volumetric imaging with minimal phototoxicity, while arivis Pro tracks cell lineages and divisions to capture the full developmental trajectory.

Functional imaging in C. elegans benefits from high speed and sensitivity. ZEISS Lightfield 4D and Airyscan Fast capture real-time calcium or sensor dynamics in intact animals, while Crossbeam EM provides ultrastructural detail for connectomic reconstruction. Together, these tools link neural activity with circuit architecture.

From locomotion to sensory-driven responses, behavior studies often require multi-worm tracking over time. ZEISS Celldiscoverer 7 and Axioscope systems allow standardized, high-throughput acquisition, while arivis Pro automates segmentation and trajectory analysis for consistent, reproducible results.

C. elegans screens can involve hundreds of conditions or genetic variants. ZEISS Celldiscoverer 7 and Axioscan streamline high-content imaging in multi-well formats, while arivis Pro provides automated analysis pipelines to quantify phenotypic changes, accelerating drug discovery and functional genomics.

C. elegans is increasingly used to model infection biology, from fungal invasion to bacterial colonization. ZEISS Airyscan confocal systems deliver the resolution and sensitivity to visualize host–pathogen interactions in vivo, revealing cellular responses and pathogen dynamics in real time.

Imaging whole animals, long-term time-lapse experiments, or multi-sample screens can generate terabyte-scale datasets. ZEISS arivis Pro provides scalable infrastructure for stitching, segmentation, and quantification, ensuring reproducible insights across experiments and enabling data sharing across teams.