Mouse Research

Mouse organs are large and optically dense, making deep imaging a challenge. ZEISS Lightsheet 7 provides whole-organ, cleared tissue imaging with minimal photodamage, while arivis Pro handles stitching and reconstruction for terabyte-scale datasets.

For high-throughput pipelines, ZEISS offers scalable solutions like the Axioscan slide scanner and Celldiscoverer 7 automated imaging system. These platforms support multi-sample acquisition in standardized formats, while arivis Pro ensures consistent, quantitative analysis across large datasets. This combination accelerates screening, reduces variability, and delivers reproducible results critical for regulatory and translational studies.

Exploratory science benefits from advanced resolution and flexibility. ZEISS Airyscan-enabled LSMs provide high sensitivity and subcellular detail, while Lattice Lightsheet enables gentle live-cell imaging of delicate structures like oocytes or developing embryos. For whole-tissue exploration, Lightsheet 7 captures cleared organs in 3D, and Crossbeam EM allows ultrastructural reconstruction. Together, these tools empower researchers to push the boundaries of biology at every scale.

ZEISS systems enable correlative workflows that bridge anatomy and physiology. With Lightfield 4D, researchers can capture high-speed functional activity such as neuronal signaling or immune cell dynamics, then seamlessly switch to Airyscan on the same LSM platform to image the same structures at near super-resolution.

Mouse studies span diverse organs such as brain, kidney, lung, and reproductive tissues. ZEISS systems are optimized for each use case: Lightsheet for cleared and intact tissues, Airyscan for high-resolution subcellular imaging, Axioscan for histological and multiplex slides, Lattice Lightsheet or Lightfield 4D for dynamic processes, and arivis Pro to unify analysis across modalities and organ systems.

Imaging cleared brains, multiplex slides, or multi-well screens can easily produce terabyte-scale datasets. ZEISS arivis Pro is built to handle this complexity, with tools for stitching, segmentation, and quantification in reproducible, shareable pipelines. This enables researchers to extract meaningful insights faster and with greater confidence.