A New Confocal Experience
Learn more about LSM Plus and Airyscan jDCV
Laser scanning microscopy is valued for its instant, high-quality imaging of optical sections and has set the imaging standard for a wide variety of samples and experiments. It’s hard to imagine how the data quality of this technology can be improved further while fully preserving its appreciated ease of use and application flexibility.
The ZEISS LSM product family, now featuring LSM Plus and Airyscan Joint Deconvolution (jDCV), is doing just that: improving literally any confocal experiment with ease, independent of detection mode or emission range.
LSM Plus
Improve spectral imaging along the complete wavelength range
This new linear Wiener filter deconvolution needs next to no interaction while still ensuring a reliable quantitative result, regardless of whether you perform classic confocal or advanced multispectral imaging including NLO and NIR. Just as in the time-tested Airyscan super-resolution processing, the underlying optical property information is adapted automatically based on objective lens, refractive index, and emission range.
- Enhanced signal to noise at high acquisition speed and low laser power—particularly useful for live cell imaging with low expression levels
- Improved resolution of spectral data with up to 36 channels in a single scan
- More spatial information and even greater resolution enhancement for bright samples that allow to close the pinhole of the LSM
- Integrated workflows to combine the advantages of LSM Plus with Airyscan super-resolution imaging




Airyscan Joint Deconvolution
Add structural information and push resolution even further
Airyscan 2 is an area detector with 32 circularly arranged detection elements. Each of these acts as a small pinhole, contributing to super-resolution information, while the complete detector area collects more light than the standard confocal setting. This produces much greater light efficiency while capturing enhanced structural information.
32 Views Mean More Information
Each of the 32 detector elements has a slightly different view on the sample, providing additional spatial information that makes Joint Deconvolution possible. This reduces the distance that can be resolved between two points even further—down to 90 nm. Your super-resolution experiments will benefit from an improved separation of single or multiple labels.




Learn More about the Technology
In these two white papers, read more about the technology behind LSM Plus and Airyscan Joint Deconvolution (jDCV).
Get the New Confocal Experience
ZEISS LSM Plus and Airyscan Joint Deconvolution (jDCV) are available as upgrades for the following systems:
LSM Plus | Airyscan jDCV | |
---|---|---|
LSM 800 |
✔ |
✔
|
LSM 880 |
- |
✔ |
LSM 900 |
✔ |
✔ |
LSM 980 |
✔ |
✔ |
Celldiscoverer 7 with LSM 900 |
✔ |
✔ |
Your compact confocal for gentle multiplex imaging and smart analysis.
Your unique confocal experience for fast and gentle multiplex imaging.
Your automated platform for live cell imaging.
Get in Contact with Us
Do you have questions about ZEISS LSM Plus or Airyscan jDCV or want to upgrade? Get in contact with one of our confocal imaging specialists.
We look forward to hearing from you!