PJ118 mouse brain slice GFPThy1 Cy3 Calretin Cy5 GAD65_Sb50_c123 — Courtesy of P. Janz, Neuropathology | University Freiburg | Germany

Microscopy applications for your laboratory

Microscopy Solutions for Neuropathology

Solutions that support research hand diagnosis of diseases of the brain and of thenervous system.

From whole brain to synapse—In stunning detail

Neuropathology is a branch of pathology that focuses on the diagnosis and research of diseases of the brain and of the nervous system. Diagnoses are necessary for individual patient treatment or for forensic requests and are typically based on the microscopic and molecular analysis of neurosurgically extracted tissue samples. Common fields of study are tumors and diseases within the central nervous system (CNS) such as glioblastomas, neurodegenerative changes, and various developmental brain disorders.

ZEISS empowers neuropathology labs and researchers with a complete imaging ecosystem that spans from whole-slide digital pathology to super-resolution and live-cell microscopy. High-resolution fluorescence and confocal systems reveal intricate brain structures and disease markers, while AI-driven platforms ZEN or arivis Cloud, streamline image analysis for consistent, reproducible results. Whole-slide scanners like the Axioscan 7 enable remote collaboration and efficient data management, making large-scale studies and multi-site diagnostics seamless. Coupled with expert training programs, sustainable manufacturing, and close partnerships with leading neuroscience institutions, ZEISS delivers the precision, reliability, and innovation that modern neuropathology demands.

Multi-scale imaging

Seamless workflow across light, X-ray, and electron microscopy, enabling anometer detail — without compromising registration.
High-sensitivity fluorescence for thick or live tissue

Capture intricate neuronal structures and dynamic processes deep inside tissue with minimal photodamage.
AI-driven analysis

Software that supports large-dataset visualization, code-free machine-learning models, and automated quantification.

High-resolution imaging for neuropathology research

Application examples for neuropathology studies

Dr. Yunfeng Hua, Shanghai Ninth People’s Hospital | China

VERSA XRM

Non-destructive 3D X-ray imaging to locate regions of interest deep inside the cochlea or brain without cutting, preserving delicate neural architecture

Cecilia S. Lu, Okinawa Institute of Science and Technology | Japan

ZEISS Lightsheet 7

Fast, gentle 3D imaging allows whole-embryo visualization at subcellular resolution with minimal photodamage

Zoological Collection of the University of Würzburg | Germany

ZEISS AXIOSCAN 7

High-throughput slide scanning captures entire brain sections in brightfield or fluorescence with uniform illumination and precise stitching

M. Paoli, Galizia Lab, University of Konstanz | Germany

ZEISS AIRYSCAN

Capture large, intact neural tissues in high resolution—directly relevant for neuropathology samples like brain slices or thick biopsies

ZEISS LSM 910

High-resolution multi-channel imaging demonstrates the ZEISS confocal’s ability to capture fine neural architecture with multiple markers simultaneously

Explore ZEISS neuroscience applications

Configure your arivis Pro Software

Advanced Image Analysis Made Easy with ZEISS

Explore our software solutions bundles available for trial and purchase online.

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ZEISS lab essentials

Your Microscope for Education and Teaching
ZEISS Primostar 1

ZEISS Primostar 1 is a durable and user-friendly microscope designed for educational applications, featuring fixed Koehler illumination that simplifies setup and ease of use.

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Your All-in-One Cell Imaging System
ZEISS Axiovert 5 digital

Axiovert 5 digital brings AI into your cell lab to ease your daily work. It will make your processes more efficient and your results more reproducible. Stay relaxed, even when there is a lot going on around you.

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Your Microscope for Digital Teaching and Routine Lab
ZEISS Primostar 3

No matter if you need a microscope for education, training or routine lab work: Primostar 3 is the easy-to-use, compact and long-lasting instrument that turns your investment into the right choice for long working hours even in the most space-limited environments.

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